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Unlike a balloon, which has a very slight pressure difference from your lungs, a helium tank is under high pressure. If you inhale directly from a tank, you're forcing a lot of helium into your lungs, which is bad for many reasons. It can cause your lungs to become overinflated and even possibly rupture (tear open) and you will quickly lose the oxygen in your lungs and blood, causing you to suffocate, which can lead to unconsciousness, brain damage, or even death. Not a good idea.

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