Brand Name Zecef
Type Pediatric Drop
Weight 125 mg/1.25 ml
Generic Cephradine
Manufacturer Gaco Pharmaceuticals Ltd.

About Zecef

Zecef Pediatric Drop (Gaco Pharmaceuticals Ltd.) is a brand medicine containing the generic Cephradine .

Medical information for Zecef Pediatric Drop 125 mg/1.25 ml

Uses, dosage, side effects, and safety details below apply to Zecef Pediatric Drop 125 mg/1.25 ml (generic: Cephradine). This is general information — consult a doctor before use.

Introduction

A semi-synthetic cephalosporin antibiotic.

Uses

Cefradine is a first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues.

Associated Conditions

  • Bacterial Sepsis
  • Bloodstream Infections
  • Osteomyelitis
  • Peritonitis
  • Respiratory Tract Infections (RTI)
  • Septic Arthritis
  • Skin and Soft Tissue Infections
  • Urogenital infection bacterial

Mechanism of Action

Cefradine is a first generation cephalosporin antibiotic with a spectrum of activity similar to Cefalexin. Cefradine, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Cefradine interferes with an autolysin inhibitor.

Route of Elimination

Over 90 percent of the drug is excreted unchanged in the urine within six hours.

Food Interactions

  • Take with or without food.

Dosage

For oral administration-
Adults:
  • Urinary tract infections: 500mg four times daily or 1g twice daily. Infections which are severe or chronic may necessitate the administration of higher doses. Where complications arise including prostatitis and epididymitis continued intensive treatment is required.
  • Respiratory tract infections: 250 to 500mg four times daily or 500mg to 1g twice daily, dependent on the site and severity of the infection.
  • Skin and soft tissue infections: 250 to 500mg four times daily or 500mg to 1g twice daily, again dependent on the site and severity of the infection.
Children:
  • Total daily dose of 25 to 50mg/kg given in two or four equally divided doses.
  • Otitis media: Total daily dose of 75 to 100mg/kg given in divided doses 6 to 12 hourly.
  • Maximum daily dosage: 4 gm
Elderly: The normal adult dose is appropriate. Patients with impaired renal or hepatic function should be monitored during treatment.

For injectable administration-
  • Adult: The usual dose is 2-4 gm daily in four equally divided doses up to 8 gm daily. For prophylaxis a single preoperative dose of 1-2 gm intramuscularly or intravenously is given.
  • Children: The dose is 50-100 mg/kg daily in four equally divided doses, up to 300 mg/kg daily in severe infection.

Frequently Asked Questions About Zecef Pediatric Drop 125 mg/1.25 ml

1. What is Zecef Pediatric Drop 125 mg/1.25 ml?

Zecef Pediatric Drop 125 mg/1.25 ml is a first-generation cephalosporin antibiotic used to treat bacterial infections in humans.

2. What types of infections does Zecef Pediatric Drop 125 mg/1.25 ml treat?

Zecef Pediatric Drop 125 mg/1.25 ml is used to treat respiratory tract infections, skin infections, urinary tract infections (UTIs), and certain ear infections.

3. How does Zecef Pediatric Drop 125 mg/1.25 ml work?

Zecef Pediatric Drop 125 mg/1.25 ml works by inhibiting bacterial cell wall synthesis, leading to bacterial death.

4. Is Zecef Pediatric Drop 125 mg/1.25 ml available over the counter?

No, Zecef Pediatric Drop 125 mg/1.25 ml is a prescription antibiotic and must be prescribed by a doctor.

5. How should I take Zecef Pediatric Drop 125 mg/1.25 ml?

Zecef Pediatric Drop 125 mg/1.25 ml should be taken exactly as prescribed by your doctor, usually with or without food.

6. What is the typical dosage of Zecef Pediatric Drop 125 mg/1.25 ml?

  • Adults: 250-500 mg every 6 hours, depending on the infection.
  • Children: Dosage is based on body weight and infection severity.

7. Can Zecef Pediatric Drop 125 mg/1.25 ml be taken on an empty stomach?

Yes, but taking it with food may help reduce stomach upset.

8. What are the common side effects of Zecef Pediatric Drop 125 mg/1.25 ml?

Common side effects include nausea, diarrhea, stomach pain, and mild skin rash.

9. Can pregnant women take Zecef Pediatric Drop 125 mg/1.25 ml?

Zecef Pediatric Drop 125 mg/1.25 ml is generally considered safe during pregnancy but should be used under medical supervision.

10. Can breastfeeding mothers take Zecef Pediatric Drop 125 mg/1.25 ml?

Yes, but small amounts may pass into breast milk. Consult your doctor before use.

11. How long does it take for Zecef Pediatric Drop 125 mg/1.25 ml to work?

Symptoms often improve within 48 hours, but the full course should be completed to prevent antibiotic resistance.

12. What should I do if I miss a dose?

Take the missed dose as soon as you remember, but skip it if it's almost time for your next dose. Do not double dose.

13. Can Zecef Pediatric Drop 125 mg/1.25 ml be used for children?

Yes, but the dosage depends on the child’s weight and the severity of the infection.

14. What should I avoid while taking Zecef Pediatric Drop 125 mg/1.25 ml?

Avoid alcohol and do not skip doses, as this can reduce the effectiveness of the antibiotic.

15. Can Zecef Pediatric Drop 125 mg/1.25 ml treat viral infections like colds or flu?

No, Zecef Pediatric Drop 125 mg/1.25 ml is only effective against bacterial infections.

16. Is Zecef Pediatric Drop 125 mg/1.25 ml safe for people with kidney disease?

People with kidney disease may require a lower dose. Consult your doctor.

17. Can I drink alcohol while taking Zecef Pediatric Drop 125 mg/1.25 ml?

It is best to avoid alcohol, as it may increase the risk of side effects like nausea and dizziness.

18. What happens if I take too much Zecef Pediatric Drop 125 mg/1.25 ml?

Overdose symptoms may include nausea, vomiting, stomach pain, or seizures. Seek medical attention immediately.

19. Does Zecef Pediatric Drop 125 mg/1.25 ml interact with other medications?

Yes, Zecef Pediatric Drop 125 mg/1.25 ml may interact with blood thinners, diuretics, and other antibiotics. Inform your doctor about all medicines you are taking.

20. Can Zecef Pediatric Drop 125 mg/1.25 ml be used for tooth infections?

Yes, Zecef Pediatric Drop 125 mg/1.25 ml may be prescribed for bacterial tooth infections.

21. Can I take Zecef Pediatric Drop 125 mg/1.25 ml for urinary tract infections (UTIs)?

Yes, Zecef Pediatric Drop 125 mg/1.25 ml is commonly prescribed for UTIs.

22. Can Zecef Pediatric Drop 125 mg/1.25 ml treat pneumonia?

Yes, Zecef Pediatric Drop 125 mg/1.25 ml can be used to treat mild to moderate pneumonia.

23. Does Zecef Pediatric Drop 125 mg/1.25 ml kill all bacteria?

No, it is effective against certain gram-positive and gram-negative bacteria.

24. Can Zecef Pediatric Drop 125 mg/1.25 ml be used for ear infections?

Yes, it is sometimes prescribed for bacterial ear infections.

25. Does Zecef Pediatric Drop 125 mg/1.25 ml cause diarrhea?

Yes, diarrhea is a possible side effect.

26. Is Zecef Pediatric Drop 125 mg/1.25 ml a penicillin?

No, but it belongs to a related class of antibiotics called cephalosporins.

27. Can I take Zecef Pediatric Drop 125 mg/1.25 ml with paracetamol?

Yes, Zecef Pediatric Drop 125 mg/1.25 ml can be taken with paracetamol if needed for pain or fever.

28. Can Zecef Pediatric Drop 125 mg/1.25 ml cause allergic reactions?

Yes, signs of an allergic reaction include rash, swelling, and difficulty breathing. Seek medical help if this occurs.

29. Does Zecef Pediatric Drop 125 mg/1.25 ml make you sleepy?

Drowsiness is not a common side effect, but some people may feel fatigued.

30. Can I stop taking Zecef Pediatric Drop 125 mg/1.25 ml if I feel better?

No, always complete the full course to prevent antibiotic resistance.

31. Can Zecef Pediatric Drop 125 mg/1.25 ml treat skin infections?

Yes, it is used for bacterial skin infections.

32. Can Zecef Pediatric Drop 125 mg/1.25 ml cause stomach pain?

Yes, mild stomach discomfort is a common side effect.

33. How should Zecef Pediatric Drop 125 mg/1.25 ml be stored?

Store at room temperature, away from moisture and heat.

34. Does Zecef Pediatric Drop 125 mg/1.25 ml cause yeast infections?

Yes, prolonged use may lead to yeast infections.

35. Can Zecef Pediatric Drop 125 mg/1.25 ml cause headaches?

Headaches are a possible but uncommon side effect.

36. Can Zecef Pediatric Drop 125 mg/1.25 ml be given intravenously?

No, Zecef Pediatric Drop 125 mg/1.25 ml is usually taken orally or via injection.

37. Can Zecef Pediatric Drop 125 mg/1.25 ml be used for food poisoning?

Only if caused by susceptible bacteria, not for viral food poisoning.

38. Can Zecef Pediatric Drop 125 mg/1.25 ml be taken long-term?

No, it is meant for short-term use only.

39. Does Zecef Pediatric Drop 125 mg/1.25 ml affect birth control pills?

It may reduce their effectiveness. Use additional contraception.

40. Can Zecef Pediatric Drop 125 mg/1.25 ml cause dizziness?

Dizziness is an uncommon but possible side effect.

41. Is Zecef Pediatric Drop 125 mg/1.25 ml safe for elderly patients?

Yes, but kidney function should be monitored.

42. Can Zecef Pediatric Drop 125 mg/1.25 ml treat bronchitis?

Yes, it is sometimes prescribed for bacterial bronchitis.

43. Can Zecef Pediatric Drop 125 mg/1.25 ml cause liver damage?

Rarely, but liver function should be monitored in long-term use.

44. Can Zecef Pediatric Drop 125 mg/1.25 ml be used for gonorrhea?

No, other antibiotics like ceftriaxone are preferred.

45. Does Zecef Pediatric Drop 125 mg/1.25 ml cause sun sensitivity?

Sun sensitivity is not a common side effect.

46. Can Zecef Pediatric Drop 125 mg/1.25 ml treat typhoid fever?

No, other antibiotics like ciprofloxacin are preferred.

47. Can Zecef Pediatric Drop 125 mg/1.25 ml cause weight loss?

Weight loss is not a common side effect.

48. Can I take Zecef Pediatric Drop 125 mg/1.25 ml if I have diabetes?

Yes, but monitor blood sugar levels as some antibiotics may affect them.

49. Can Zecef Pediatric Drop 125 mg/1.25 ml be used for sinus infections?

Yes, it is sometimes prescribed for bacterial sinus infections.

50. How long should I take Zecef Pediatric Drop 125 mg/1.25 ml?

Take it for the full duration prescribed by your doctor.

Medical review

Last reviewed: 24 Jul 2026

Medically reviewed by:

This is general information, not personal medical advice. Consult a doctor before taking any medicine.

Taking medicines without doctor's advice can cause long-term problems.
Dr. Uttom Kumar Shet

Dr. Uttom Kumar Shet

Dental Implant Specialist and Course Director (Osstem Implant), Maxillofacial Surgery

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Dr. Md. Omar Faruk

Dr. Md. Omar Faruk

Medicine & Diabetes Specialist

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Dr. Hasan Zahid

Dr. Hasan Zahid

Newborn & Child Diseases Specialist

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