Introduction

Uniclor Pediatric Drop 125 mg/1.25 ml is a prescription drug used for the treatment of certain bacterial infections, such as pneumonia, bronchitis, ear, nose, throat, urinary tract and skin. It is in the cephalosporin class of antibiotics.

Uses For

Uniclor Pediatric Drop 125 mg/1.25 ml is primarily used to treat a variety of bacterial infections, including:
  • Pneumonia
  • Bronchitis
  • Ear, nose, throat infections
  • Urinary tract infections
  • Skin infections

Mechanism of Action

Uniclor Pediatric Drop 125 mg/1.25 ml works by binding to the cell wall of bacteria and preventing them from building and maintaining their protective layer, thus killing the bacteria.

How Long Does it Take to Work

It usually takes 2-3 days for the symptoms of a bacterial infection to improve after beginning treatment with Uniclor Pediatric Drop 125 mg/1.25 ml, although some people may notice improvements within just a few hours.

Absorption

Uniclor Pediatric Drop 125 mg/1.25 ml is well and rapidly absorbed in the gastrointestinal tract, reaching peak concentrations 1-2 hours post-administration.

Route of Elimination

Uniclor Pediatric Drop 125 mg/1.25 ml is eliminated predominantly in the urine with a small amount excreted in the feces.

Dosage

Capsule: Adult dose: The usual dose is 250 mg every 8 hourly. For severe infections or those caused by less susceptible organisms, doses may be doubled with a maximum dosage of 4 g/day. In case of β-hemolytic Streptococcal infections, therapy should be administered for at least 10 days.

Powder for suspension & Pediatric drops: Children: The usual daily dosage for paediatric patients over 1 month is 20 mg/kg/day in divided doses every 8 hours. In serious infections such as otitis media and infections caused by less susceptible organisms, 40 mg/kg/day are recommended, with a maximum dosage of 1 g/day. Safety and effectiveness of Cefaclor for use in infants less than 1 month of age have not been established.

<1 year (9 kg):
  • Powder for suspension: ½ tsp three times daily
  • Pediatric drops: 0.625 ml three times daily
1-5 years (9 kg-18 kg):
  • Powder for suspension: 1 tsp three times daily
  • Pediatric drops: 1.25 ml three times daily
Over 5 years:
  • Powder for suspension: 2 tsp three times daily
In renal impairment: Cefaclor may be administered in the presence of impaired renal function. Dose adjustments for patients with moderate or sever renal impairment are not usually required.

In patients undergoing haemodialysis: Haemodialysis shortens serum half-life by 25-30%. In patients undergoing haemodialysis, a predialysis loading dose of 250 mg-1 g is recommended. A maintaining dose of 250-500 mg every 6 hourly during interdialytic period may be used.

Geriatric use: Clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out. The dosage for Uniclor Pediatric Drop 125 mg/1.25 ml depends on the patient, type of infection, the severity of the infection, and the patient’s age. The usual adult dose is one 250-milligram capsule, two to three times a day, or one 500-milligram capsule, two times a day. It is recommended to take the capsules with food.

Administration

Uniclor Pediatric Drop 125 mg/1.25 ml is administered orally in the form of a capsule. It should be taken with food to reduce the risk of irritation to the gastrointestinal tract.

Side Effect

Common side effects associated with Uniclor Pediatric Drop 125 mg/1.25 ml may include:
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Mild skin rash

Toxicity

Uniclor Pediatric Drop 125 mg/1.25 ml is not associated with a high incidence of toxicity in humans.

Precaution

Patients taking Uniclor Pediatric Drop 125 mg/1.25 ml should be warned to avoid overuse of the drug and should be regularly monitored for signs of adverse reactions. Patients should also be warned to notify their healthcare provider immediately if they develop any signs of an allergic reaction, including rash, hives, difficulty breathing, swelling of the face/lips/tongue or other signs of an allergic reaction.

Interaction

Uniclor Pediatric Drop 125 mg/1.25 ml may interact with other medications with which it is not compatible. It is important to tell your healthcare provider about all the other medications you are taking, including herbal supplements and over-the-counter medications.

Disease Interaction

Uniclor Pediatric Drop 125 mg/1.25 ml can cause an increased risk of bleeding in patients with a history of coagulation disorders or kidney disease. It should also be used with caution in liver disease and patients with a history of seizures.

Drug Interaction

Uniclor Pediatric Drop 125 mg/1.25 ml may interact with other medications, including anticoagulants, probenecid, or other cephalosporin antibiotics.

Food Interactions

Uniclor Pediatric Drop 125 mg/1.25 ml should not be taken with food or milk. Taking it with food or milk may reduce the absorption and effectiveness of the medication.

Pregnancy Use

Uniclor Pediatric Drop 125 mg/1.25 ml should be used with extreme caution in pregnant women as it can harm the fetus. It is recommended to consult a healthcare professional about the benefits and risks of taking Uniclor Pediatric Drop 125 mg/1.25 ml in pregnant women.

Lactation Use

Uniclor Pediatric Drop 125 mg/1.25 ml is generally considered safe for use during lactation, but should be used with caution. It is recommended to consult a healthcare provider for more information regarding the safety of Uniclor Pediatric Drop 125 mg/1.25 ml during lactation.

Acute Overdose

Symptoms of an acute overdose of Uniclor Pediatric Drop 125 mg/1.25 ml may include nausea, vomiting, and diarrhea. If an overdose is suspected, seek immediate medical attention.

Contraindication

Uniclor Pediatric Drop 125 mg/1.25 ml should not be used if a patient has an allergy or hypersensitivity to any of its active or inactive ingredients.

Use Direction

It is important to follow the instructions given by your healthcare provider. Uniclor Pediatric Drop 125 mg/1.25 ml should be taken orally as directed by your healthcare provider. The usual adult dose is one 250-milligram capsule, two to three times a day, or one 500-milligram capsule, two times a day. It is recommended to take the capsules with food.

Storage Condition

Uniclor Pediatric Drop 125 mg/1.25 ml should be stored at room temperature away from sunlight andin a secure, preferably locked area. It should also be stored away from children.

Volume of Distribution

Approximately 0.1-0.2 L/kg for cefaclor.

Half Life

Approximately 1.5-2.5 hours for cefaclor.

Clearance

Approximately 0.2 L/h/kg for cefaclor.

See in details version Uniclor Pediatric Drop 125 mg/1.25 ml also Uniclor Pediatric Drop 125 mg/1.25 ml in bangla

Some Frequently Asked Questions About Uniclor Pediatric Drop 125 mg/1.25 ml

1. What is Uniclor Pediatric Drop 125 mg/1.25 ml?

Uniclor Pediatric Drop 125 mg/1.25 ml is a second-generation cephalosporin antibiotic used to treat bacterial infections.

2. What infections does Uniclor Pediatric Drop 125 mg/1.25 ml treat?

It is used to treat respiratory tract infections, skin infections, urinary tract infections (UTIs), otitis media (ear infections), and sinus infections.

3. How does Uniclor Pediatric Drop 125 mg/1.25 ml work?

It works by inhibiting bacterial cell wall synthesis, leading to bacterial death.

4. Is Uniclor Pediatric Drop 125 mg/1.25 ml available over the counter?

No, it is a prescription-only antibiotic.

5. How should I take Uniclor Pediatric Drop 125 mg/1.25 ml?

Take it exactly as prescribed by your doctor, usually with or without food.

6. What is the typical dosage of Uniclor Pediatric Drop 125 mg/1.25 ml?

  • Adults: 250-500 mg every 8 hours.
  • Children: Dosage is based on weight and infection severity.

7. Can Uniclor Pediatric Drop 125 mg/1.25 ml be taken on an empty stomach?

Yes, but taking it with food may help reduce stomach upset.

8. What are the common side effects of Uniclor Pediatric Drop 125 mg/1.25 ml?

Common side effects include nausea, diarrhea, vomiting, stomach pain, headache, and skin rash.

9. Can pregnant women take Uniclor Pediatric Drop 125 mg/1.25 ml?

It is generally considered safe in pregnancy, but should only be used if necessary and prescribed by a doctor.

10. Can breastfeeding mothers take Uniclor Pediatric Drop 125 mg/1.25 ml?

Small amounts may pass into breast milk. Consult your doctor before use.

11. How long does it take for Uniclor Pediatric Drop 125 mg/1.25 ml to work?

Symptoms usually improve within 48 hours, but the full course should be completed.

12. What should I do if I miss a dose?

Take it as soon as you remember, but skip it if it's almost time for your next dose. Do not double dose.

13. Can Uniclor Pediatric Drop 125 mg/1.25 ml be used for children?

Yes, but the dosage depends on the child’s weight and severity of the infection.

14. What should I avoid while taking Uniclor Pediatric Drop 125 mg/1.25 ml?

Avoid alcohol and do not skip doses.

15. Can Uniclor Pediatric Drop 125 mg/1.25 ml treat viral infections like colds or flu?

No, it is only effective against bacterial infections.

16. Is Uniclor Pediatric Drop 125 mg/1.25 ml safe for people with kidney disease?

Patients with kidney disease may require a lower dose. Consult your doctor.

17. Can I drink alcohol while taking Uniclor Pediatric Drop 125 mg/1.25 ml?

It is best to avoid alcohol, as it may increase the risk of side effects.

18. What happens if I take too much Uniclor Pediatric Drop 125 mg/1.25 ml?

Overdose symptoms may include nausea, vomiting, seizures, or severe diarrhea. Seek medical help immediately.

19. Does Uniclor Pediatric Drop 125 mg/1.25 ml interact with other medications?

Yes, it may interact with blood thinners, diuretics, and certain antibiotics.

20. Can Uniclor Pediatric Drop 125 mg/1.25 ml be used for tooth infections?

Yes, it may be prescribed for bacterial tooth infections.

21. Can I take Uniclor Pediatric Drop 125 mg/1.25 ml for urinary tract infections (UTIs)?

Yes, it is commonly prescribed for UTIs.

22. Can Uniclor Pediatric Drop 125 mg/1.25 ml treat pneumonia?

Yes, it can be used to treat mild to moderate pneumonia.

23. Does Uniclor Pediatric Drop 125 mg/1.25 ml kill all bacteria?

No, it is effective against certain gram-positive and gram-negative bacteria.

24. Can Uniclor Pediatric Drop 125 mg/1.25 ml be used for ear infections?

Yes, it is commonly used to treat otitis media.

25. Does Uniclor Pediatric Drop 125 mg/1.25 ml cause diarrhea?

Yes, diarrhea is a possible side effect.

26. Is Uniclor Pediatric Drop 125 mg/1.25 ml a penicillin?

No, but it is related to penicillin antibiotics.

27. Can I take Uniclor Pediatric Drop 125 mg/1.25 ml with paracetamol?

Yes, they can be taken together.

28. Can Uniclor Pediatric Drop 125 mg/1.25 ml cause allergic reactions?

Yes, seek medical help if you experience rash, swelling, or difficulty breathing.

29. Does Uniclor Pediatric Drop 125 mg/1.25 ml make you sleepy?

Drowsiness is not a common side effect.

30. Can I stop taking Uniclor Pediatric Drop 125 mg/1.25 ml if I feel better?

No, complete the full course to prevent antibiotic resistance.

31. Can Uniclor Pediatric Drop 125 mg/1.25 ml treat skin infections?

Yes, it is used for bacterial skin infections.

32. Can Uniclor Pediatric Drop 125 mg/1.25 ml cause stomach pain?

Yes, mild stomach discomfort is common.

33. How should Uniclor Pediatric Drop 125 mg/1.25 ml be stored?

Store at room temperature, away from moisture and heat.

34. Does Uniclor Pediatric Drop 125 mg/1.25 ml cause yeast infections?

Yes, prolonged use may lead to yeast infections.

35. Can Uniclor Pediatric Drop 125 mg/1.25 ml cause headaches?

Yes, headaches are a possible side effect.

36. Can Uniclor Pediatric Drop 125 mg/1.25 ml treat bronchitis?

Yes, it is sometimes used for bacterial bronchitis.

37. Can Uniclor Pediatric Drop 125 mg/1.25 ml cause liver damage?

Rarely, but liver function should be monitored in long-term use.

38. Can Uniclor Pediatric Drop 125 mg/1.25 ml be used for gonorrhea?

No, other antibiotics like ceftriaxone are preferred.

39. Does Uniclor Pediatric Drop 125 mg/1.25 ml affect birth control pills?

It may reduce their effectiveness. Use additional contraception.

40. Can Uniclor Pediatric Drop 125 mg/1.25 ml cause dizziness?

Dizziness is an uncommon but possible side effect.

41. Can Uniclor Pediatric Drop 125 mg/1.25 ml treat sinus infections?

Yes, it is used for bacterial sinus infections.

42. Can I take Uniclor Pediatric Drop 125 mg/1.25 ml if I have diabetes?

Yes, but monitor blood sugar levels.

43. How long should I take Uniclor Pediatric Drop 125 mg/1.25 ml?

Follow your doctor’s prescription, usually 7-14 days.

*** Taking medicines without doctor's advice can cause long-term problems.
Dr. Md. Nurul Islam

Dr. Md. Nurul Islam

Child & Adolescent Diseases Specialist

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Dr. Md. Zahirul Alam

Dr. Md. Zahirul Alam

Child Diseases Specialist

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