Starzyl Tablet

Starzyl Tablet 400 mg

Starzyl Tablet 400 mg is an antibiotic that is used to treat a wide variety of bacterial infections. It can also be used to treat certain parasitic infections. Starzyl Tablet 400 mg works by stopping the growth of bacteria and certain parasites. It is effective against a wide range of intestinal, facial and metabolic infections.

Uses for Starzyl Tablet 400 mg

Starzyl Tablet 400 mg is used to treat a wide range of bacterial and certain parasitic infections. These include: bacterial vaginosis, trichomoniasis, giardiasis, dracunculiasis, amebiasis and certain anaerobic bacterial infections such as pelvic inflammatory disease, abscesses and intra-abdominal infections. It can also be used to treat Clostridium difficile-associated diarrhea and pseudomembranous colitis.

Mechanism Of Action

Starzyl Tablet 400 mg works by inhibiting the growth of bacteria and certain parasitic organisms. It acts on DNA, the genetic material in the body which carries instructions to make proteins and enzymes necessary for cell growth. It is believed that metronidazole works by blocking the action of an enzyme involved in DNA replication, thereby preventing the replication of the bacterial and parasitic organisms.

How Long Does It Take To Work?

The effects of metronidazole are usually seen within a few hours of administration. It usually takes several days to weeks before the full effects of the medication are experienced.

Absorption

Starzyl Tablet 400 mg is rapidly and completely absorbed after oral administration. The maximum plasma concentrations are reached within one to two hours.

Route Of Elimination

Starzyl Tablet 400 mg is rapidly eliminated from the body in the form of metabolites and other breakdown products. The metabolites are mainly excreted unchanged in the urine and to a lesser extent in the feces. Starzyl Tablet 400 mg is also known to undergo hepatic metabolism.

Dosage

Tablet and Suspension:

• 200 mg tid or 400 mg bid for 7 days
• 800 mg in the morning and 1-2 gm at night for 2 days
• 2 gm as a single dose for 1 days

• Children 7-10 yrs: 100 mg tid
• Children 3-7 yrs: 100 mg bid
• Children 1-3 yrs: 50 mg tid

• 800 mg tid for 5 days

• Children 7-10 yrs: 400 mg tid
• Children 3-7 yrs: 200 mg qid
• Children 1-3 yrs: 200 mg tid

• 400-800 mg tid for 5-10 days

• Children 7-10 yrs: 200-400 mg tid
• Children 3-7 yrs: 100-200 mg qid
• Children 1-3 yrs: 100-200 mg tid

• 2 gm once daily for 3 days

• Children 7-10 yrs: 1 gm once daily
• Children 3-7 yrs: 600-800 mg once daily
• Children 1-3 yrs: 500 mg once daily

• 200 mg tid for 3 days

• Children 7-10 yrs: 100 mg tid
• Children 3-7 yrs: 100 mg bid
• Children 1-3 yrs: 50 mg tid

• 200 mg tid for 3-7 days

• 400 mg bid for 7 days
• 2 gm as a single dose for 1 days

• 400 mg tid for 7 days

• 800 mg initially and then 400 mg tid for 7 days

• Children 1-10 yrs: 7.5 mg/kg tid

• 400 mg tid started 24  hours before  surgery for 1 days

• Children 1-10 yrs: 7.5 mg/kg tid

Vaginal Gel:

Suppository:

• Adults: 1 g every 8 hours for 3 days, then 1 g every 12 hours.
• Children: 5-10 years: 500 mg every 8 hours for 3 days, then every 12 hours, Over 10 years adult dose.

• Adults: 1 g 2 hours before surgery; up to 3 further doses of 1 g may be given every 8 hours for high risk procedures.
• Children: 5-10 years: 500 mg 2 hours before surgery; up to 3 further doses of 500 mg may be given every 8 hours for high risk procedures.

IV Infusion:

• Adults and children over 12 years: Infuse 500 mg 8 hourly at a rate of 5 ml/minute and a maximum of 4 g should not be exceeded during a 24-hour period. Treatment for 7 days is sufficient for most patients, but treatment can be extended, especially for cases where reinfection is likely. For surgical prophylaxis, administration shortly before surgery should be followed by 8-hourly doses for the next 24 hours.
• Children under 12 years: 7.5 mg/kg body weight/day every 8 hours at a rate of 5 ml/minute.

Starzyl Tablet 400 mg is available as a oral tablet, topical gel, and intravenous (IV) infusion. The typical adult dose of metronidazole for serious bacterial infections is 500 mg every 8 hours for 7 to 10 days.

Administration

Starzyl Tablet 400 mg can be taken orally with or without food. It is usually taken twice a day with meals or snacks. The extended-release tablets should be taken with food. Starzyl Tablet 400 mg can also be given by intravenous (IV) infusion or injection. It should be administered slowly over 2 to 5 minutes.

Side Effect

The most common side effects of metronidazole are nausea, vomiting, headache, metallic taste, abdominal cramps and diarrhea. Other rare but possible side effects include skin rash, vertigo, blurred vision, anxiety, restlessness, dizziness and confusion.

Toxicity

Starzyl Tablet 400 mg is highly toxic in the presence of heavy metals. It should be used with caution and only with the guidance of a healthcare professional in patients with a history of kidney or liver disease.

Precautions

Starzyl Tablet 400 mg should be used with caution in patients with a history of blood disorders, kidney or liver disease and alcohol abuse. It should also not be used in pregnant women or nursing mothers. Patients should be monitored for potential side effects and instructed to contact their healthcare provider if any occur.

Interactions

Starzyl Tablet 400 mg should not be used in patients taking anticoagulants such as warfarin, as it may increase the risk of bleeding. In addition, caffeine, alcohol, lithium, phenytoin, carbamazepine and certain antibiotics such as chloramphenicol and ciprofloxacin may also interact with metronidazole, and caution should be exercised when these medications are taken together.

Disease Interaction

Starzyl Tablet 400 mg should be used with caution in patients with a history of liver disease, Crohn's disease and drowsiness. It should also not be used in patients with a history of kidney or liver disease.

Drug Interaction

Starzyl Tablet 400 mg should not be used in combination with other antibacterial agents such as erythromycin or clarithromycin, as the combination may increase the risk of side effects. In addition, it should not be used in combination with anticoagulants such as warfarin, as it may increase the risk of bleeding. Other drugs that may interact with metronidazole include lithium, phenytoin, caffeine, alcohol, carbamazepine and certain antibiotics such as chloramphenicol and ciprofloxacin.

Food Interaction

Starzyl Tablet 400 mg should be taken with food or a snack to minimize the risk of gastrointestinal side effects. Taking the medication with alcohol or in combination with other medicines may increase the risk of side effects.

Pregnancy Use

Starzyl Tablet 400 mg should be avoided in pregnant women due to the potential risk of teratogenicity or fetal malformation. It should also be avoided in women who are breastfeeding due to a lack of safety data in this population.

Lactation Use

Starzyl Tablet 400 mg should not be used in patients who are breastfeeding due to a lack of safety data in this population.

Acute Overdose

An acute overdose of metronidazole can cause nausea, vomiting, abdominal pain, coma and seizures. Treatment of an overdose is supportive and symptomatic. Charcoal may be used to absorb any remaining medication.

Contraindication

Starzyl Tablet 400 mg is contraindicated in patients with a known hypersensitivity to the drug. It should also not be used in pregnant women or nursing mothers.

Use Direction

Starzyl Tablet 400 mg should be taken according to the instructions of a healthcare professional. Patients should take the medication exactly as prescribed and continue to take it for the prescribed duration of time. It is important not to miss doses or stop taking the medication early.

Storage Condition

Starzyl Tablet 400 mg should be stored at room temperature, away from direct light and moisture. Patients should keep the medication in a secure, dry place where children and pets cannot access it.

Volume Of Distribution

Starzyl Tablet 400 mg has a large volume of distribution and has been detected in saliva, sputum, urine, bile and feces.

Half Life

The elimination half-life of metronidazole is approximately 8 hours in healthy individuals.

Clearance

Starzyl Tablet 400 mg is primarily eliminated via hepatic metabolism, followed by biliary excretion. It is also metabolized via non-enzymatic pathways such as oxidation and hydrolysis.

See in details version Starzyl Tablet 400 mg also Starzyl Tablet 400 mg in bangla

Some Frequently Asked Questions About Starzyl Tablet 400 mg

1. What is Starzyl Tablet 400 mg used for?

Starzyl Tablet 400 mg is an antibiotic and antiprotozoal medication used to treat bacterial and parasitic infections.

2. What types of infections does Starzyl Tablet 400 mg treat?

• Bacterial infections of the stomach, skin, and joints
• Dental infections
• Amoebiasis (intestinal and liver infections caused by amoebas)
• Giardiasis (intestinal infection caused by parasites)
• Trichomoniasis (a sexually transmitted infection)
• Bacterial vaginosis
• Pseudomembranous colitis (C. difficile infection)

3. How does Starzyl Tablet 400 mg work?

It kills bacteria and parasites by interfering with their DNA, preventing them from multiplying.

4. Is Starzyl Tablet 400 mg an antibiotic?

Yes, it is a type of antibiotic specifically effective against anaerobic bacteria and certain parasites.

5. Can Starzyl Tablet 400 mg be used for viral infections?

No, Starzyl Tablet 400 mg does not work against viral infections like the flu or the common cold.

6. How should I take Starzyl Tablet 400 mg?

Take it exactly as prescribed by your doctor, with or without food. Swallow the tablet whole with water.

7. What are the common side effects of Starzyl Tablet 400 mg?

• Nausea
• Metallic taste in the mouth
• Diarrhea
• Dizziness
• Loss of appetite
• Headache

8. Can I drink alcohol while taking Starzyl Tablet 400 mg?

No, consuming alcohol while on Starzyl Tablet 400 mg can cause severe nausea, vomiting, and headaches.

9. How long does it take for Starzyl Tablet 400 mg to start working?

Most people start feeling better within 24 to 48 hours of starting treatment.

10. Can Starzyl Tablet 400 mg cause a yeast infection?

Yes, prolonged use may lead to yeast infections as it disrupts the natural balance of bacteria.

11. What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one.

12. Can I take Starzyl Tablet 400 mg if I am pregnant?

It is usually safe but should be used under a doctor’s supervision, especially in the first trimester.

13. Is Starzyl Tablet 400 mg safe while breastfeeding?

It can pass into breast milk. Consult your doctor before using it while breastfeeding.

14. Can Starzyl Tablet 400 mg cause allergic reactions?

Yes, signs of an allergic reaction include rash, itching, swelling, and difficulty breathing. Seek medical help immediately.

15. What should I do if I overdose?

Seek emergency medical help if you experience severe nausea, vomiting, seizures, or numbness.

16. Can Starzyl Tablet 400 mg be used for stomach ulcers?

Yes, it is sometimes used in combination with other drugs to treat stomach ulcers caused by H. pylori.

17. Can Starzyl Tablet 400 mg cause dark urine?

Yes, it can cause dark-colored urine, which is usually harmless.

18. How long should I take Starzyl Tablet 400 mg?

Complete the full course prescribed by your doctor, even if symptoms improve earlier.

19. Can I take Starzyl Tablet 400 mg with food?

Yes, taking it with food can help reduce stomach discomfort.

20. Can I take Starzyl Tablet 400 mg if I have liver disease?

People with liver disease should take it with caution and may need a lower dose.

21. Can Starzyl Tablet 400 mg cause dizziness?

Yes, dizziness is a common side effect. Avoid driving or operating heavy machinery if you feel dizzy.

22. Can I take Starzyl Tablet 400 mg with other antibiotics?

It is sometimes combined with other antibiotics, but only under a doctor’s guidance.

23. Is Starzyl Tablet 400 mg available over the counter?

No, it requires a doctor’s prescription.

24. Can Starzyl Tablet 400 mg cause headaches?

Yes, headaches are a possible side effect.

25. Can I take Starzyl Tablet 400 mg if I have kidney disease?

Yes, but your doctor may adjust your dose based on kidney function.

26. Can I stop taking Starzyl Tablet 400 mg once I feel better?

No, stopping early can lead to incomplete treatment and recurrence of infection.

27. Can Starzyl Tablet 400 mg be used for urinary tract infections (UTIs)?

It is not commonly used for UTIs unless caused by certain bacteria.

28. Can Starzyl Tablet 400 mg cause stomach pain?

Yes, stomach discomfort is a common side effect.

29. Can I take Starzyl Tablet 400 mg with probiotics?

Yes, probiotics may help reduce stomach upset and prevent yeast infections.

30. Can Starzyl Tablet 400 mg cause weight loss?

Loss of appetite may lead to mild weight loss.

31. Can Starzyl Tablet 400 mg treat acne?

Topical Starzyl Tablet 400 mg is used to treat rosacea, but not regular acne.

32. Can Starzyl Tablet 400 mg cause depression?

In rare cases, it may cause mood changes.

33. Is Starzyl Tablet 400 mg safe for children?

Yes, but the dose must be adjusted based on age and weight.

34. Can I take Starzyl Tablet 400 mg if I have diabetes?

Yes, but it may cause changes in blood sugar levels.

35. Does Starzyl Tablet 400 mg interact with birth control?

It does not reduce birth control effectiveness but can cause nausea and vomiting, which may affect pill absorption.

36. Can Starzyl Tablet 400 mg cause muscle pain?

Rarely, it may cause muscle pain or weakness.

37. Can Starzyl Tablet 400 mg be used for ear infections?

It is not commonly used for ear infections unless prescribed.

38. Can I take Starzyl Tablet 400 mg with painkillers?

Yes, but avoid NSAIDs like ibuprofen if you have stomach issues.

39. Can Starzyl Tablet 400 mg cause hallucinations?

In rare cases, neurological side effects like confusion or hallucinations may occur.

40. Can I take Starzyl Tablet 400 mg if I have seizures?

Use with caution if you have a history of seizures.

41. Can Starzyl Tablet 400 mg cause mouth sores?

Yes, some people experience mouth irritation or a metallic taste.

42. Can Starzyl Tablet 400 mg cause high blood pressure?

It does not typically affect blood pressure.

43. Can I take Starzyl Tablet 400 mg for colds or flu?

No, it is not effective against viral infections.

44. Can Starzyl Tablet 400 mg treat pneumonia?

It is not commonly used for pneumonia unless caused by anaerobic bacteria.

45. Can Starzyl Tablet 400 mg affect sleep?

Some people may experience insomnia or drowsiness.

46. Can I take Starzyl Tablet 400 mg for food poisoning?

It is only used for certain bacterial causes of food poisoning.

47. Can Starzyl Tablet 400 mg be used for dog infections?

Yes, veterinarians may prescribe it for pets, but never use human medicine on animals without guidance.

48. Can Starzyl Tablet 400 mg be used as a painkiller?

No, it is not a pain reliever.

49. Can Starzyl Tablet 400 mg be used for dental infections?

Yes, it is commonly used for dental abscesses and gum infections.

50. Can Starzyl Tablet 400 mg cause ringing in the ears?

Tinnitus is a rare side effect.