Brand Name Sefin DS
Type Powder for Suspension
Weight 250 mg/5 ml
Generic Cephradine
Manufacturer Orion Pharma Ltd.
Price 50 ml bottle: ৳ 60.42

About Sefin DS

Sefin DS Powder for Suspension (Orion Pharma Ltd.) is a brand medicine containing the generic Cephradine . Current listed price in Bangladesh: 50 ml bottle: ৳ 60.42.

Medical information for Sefin DS Powder for Suspension 250 mg/5 ml

Uses, dosage, side effects, and safety details below apply to Sefin DS Powder for Suspension 250 mg/5 ml (generic: Cephradine). This is general information — consult a doctor before use.

Introduction

A semi-synthetic cephalosporin antibiotic.

Uses

Cefradine is a first-generation cephalosporin antibiotic used in the treatment of bacterial infections of the respiratory and urinary tracts and of the skin and soft tissues.

Associated Conditions

  • Bacterial Sepsis
  • Bloodstream Infections
  • Osteomyelitis
  • Peritonitis
  • Respiratory Tract Infections (RTI)
  • Septic Arthritis
  • Skin and Soft Tissue Infections
  • Urogenital infection bacterial

Mechanism of Action

Cefradine is a first generation cephalosporin antibiotic with a spectrum of activity similar to Cefalexin. Cefradine, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Cefradine interferes with an autolysin inhibitor.

Route of Elimination

Over 90 percent of the drug is excreted unchanged in the urine within six hours.

Food Interactions

  • Take with or without food.

Dosage

For oral administration-
Adults:
  • Urinary tract infections: 500mg four times daily or 1g twice daily. Infections which are severe or chronic may necessitate the administration of higher doses. Where complications arise including prostatitis and epididymitis continued intensive treatment is required.
  • Respiratory tract infections: 250 to 500mg four times daily or 500mg to 1g twice daily, dependent on the site and severity of the infection.
  • Skin and soft tissue infections: 250 to 500mg four times daily or 500mg to 1g twice daily, again dependent on the site and severity of the infection.
Children:
  • Total daily dose of 25 to 50mg/kg given in two or four equally divided doses.
  • Otitis media: Total daily dose of 75 to 100mg/kg given in divided doses 6 to 12 hourly.
  • Maximum daily dosage: 4 gm
Elderly: The normal adult dose is appropriate. Patients with impaired renal or hepatic function should be monitored during treatment.

For injectable administration-
  • Adult: The usual dose is 2-4 gm daily in four equally divided doses up to 8 gm daily. For prophylaxis a single preoperative dose of 1-2 gm intramuscularly or intravenously is given.
  • Children: The dose is 50-100 mg/kg daily in four equally divided doses, up to 300 mg/kg daily in severe infection.

Frequently Asked Questions About Sefin DS Powder for Suspension 250 mg/5 ml

1. What is Sefin DS Powder for Suspension 250 mg/5 ml?

Sefin DS Powder for Suspension 250 mg/5 ml is a first-generation cephalosporin antibiotic used to treat bacterial infections in humans.

2. What types of infections does Sefin DS Powder for Suspension 250 mg/5 ml treat?

Sefin DS Powder for Suspension 250 mg/5 ml is used to treat respiratory tract infections, skin infections, urinary tract infections (UTIs), and certain ear infections.

3. How does Sefin DS Powder for Suspension 250 mg/5 ml work?

Sefin DS Powder for Suspension 250 mg/5 ml works by inhibiting bacterial cell wall synthesis, leading to bacterial death.

4. Is Sefin DS Powder for Suspension 250 mg/5 ml available over the counter?

No, Sefin DS Powder for Suspension 250 mg/5 ml is a prescription antibiotic and must be prescribed by a doctor.

5. How should I take Sefin DS Powder for Suspension 250 mg/5 ml?

Sefin DS Powder for Suspension 250 mg/5 ml should be taken exactly as prescribed by your doctor, usually with or without food.

6. What is the typical dosage of Sefin DS Powder for Suspension 250 mg/5 ml?

  • Adults: 250-500 mg every 6 hours, depending on the infection.
  • Children: Dosage is based on body weight and infection severity.

7. Can Sefin DS Powder for Suspension 250 mg/5 ml be taken on an empty stomach?

Yes, but taking it with food may help reduce stomach upset.

8. What are the common side effects of Sefin DS Powder for Suspension 250 mg/5 ml?

Common side effects include nausea, diarrhea, stomach pain, and mild skin rash.

9. Can pregnant women take Sefin DS Powder for Suspension 250 mg/5 ml?

Sefin DS Powder for Suspension 250 mg/5 ml is generally considered safe during pregnancy but should be used under medical supervision.

10. Can breastfeeding mothers take Sefin DS Powder for Suspension 250 mg/5 ml?

Yes, but small amounts may pass into breast milk. Consult your doctor before use.

11. How long does it take for Sefin DS Powder for Suspension 250 mg/5 ml to work?

Symptoms often improve within 48 hours, but the full course should be completed to prevent antibiotic resistance.

12. What should I do if I miss a dose?

Take the missed dose as soon as you remember, but skip it if it's almost time for your next dose. Do not double dose.

13. Can Sefin DS Powder for Suspension 250 mg/5 ml be used for children?

Yes, but the dosage depends on the child’s weight and the severity of the infection.

14. What should I avoid while taking Sefin DS Powder for Suspension 250 mg/5 ml?

Avoid alcohol and do not skip doses, as this can reduce the effectiveness of the antibiotic.

15. Can Sefin DS Powder for Suspension 250 mg/5 ml treat viral infections like colds or flu?

No, Sefin DS Powder for Suspension 250 mg/5 ml is only effective against bacterial infections.

16. Is Sefin DS Powder for Suspension 250 mg/5 ml safe for people with kidney disease?

People with kidney disease may require a lower dose. Consult your doctor.

17. Can I drink alcohol while taking Sefin DS Powder for Suspension 250 mg/5 ml?

It is best to avoid alcohol, as it may increase the risk of side effects like nausea and dizziness.

18. What happens if I take too much Sefin DS Powder for Suspension 250 mg/5 ml?

Overdose symptoms may include nausea, vomiting, stomach pain, or seizures. Seek medical attention immediately.

19. Does Sefin DS Powder for Suspension 250 mg/5 ml interact with other medications?

Yes, Sefin DS Powder for Suspension 250 mg/5 ml may interact with blood thinners, diuretics, and other antibiotics. Inform your doctor about all medicines you are taking.

20. Can Sefin DS Powder for Suspension 250 mg/5 ml be used for tooth infections?

Yes, Sefin DS Powder for Suspension 250 mg/5 ml may be prescribed for bacterial tooth infections.

21. Can I take Sefin DS Powder for Suspension 250 mg/5 ml for urinary tract infections (UTIs)?

Yes, Sefin DS Powder for Suspension 250 mg/5 ml is commonly prescribed for UTIs.

22. Can Sefin DS Powder for Suspension 250 mg/5 ml treat pneumonia?

Yes, Sefin DS Powder for Suspension 250 mg/5 ml can be used to treat mild to moderate pneumonia.

23. Does Sefin DS Powder for Suspension 250 mg/5 ml kill all bacteria?

No, it is effective against certain gram-positive and gram-negative bacteria.

24. Can Sefin DS Powder for Suspension 250 mg/5 ml be used for ear infections?

Yes, it is sometimes prescribed for bacterial ear infections.

25. Does Sefin DS Powder for Suspension 250 mg/5 ml cause diarrhea?

Yes, diarrhea is a possible side effect.

26. Is Sefin DS Powder for Suspension 250 mg/5 ml a penicillin?

No, but it belongs to a related class of antibiotics called cephalosporins.

27. Can I take Sefin DS Powder for Suspension 250 mg/5 ml with paracetamol?

Yes, Sefin DS Powder for Suspension 250 mg/5 ml can be taken with paracetamol if needed for pain or fever.

28. Can Sefin DS Powder for Suspension 250 mg/5 ml cause allergic reactions?

Yes, signs of an allergic reaction include rash, swelling, and difficulty breathing. Seek medical help if this occurs.

29. Does Sefin DS Powder for Suspension 250 mg/5 ml make you sleepy?

Drowsiness is not a common side effect, but some people may feel fatigued.

30. Can I stop taking Sefin DS Powder for Suspension 250 mg/5 ml if I feel better?

No, always complete the full course to prevent antibiotic resistance.

31. Can Sefin DS Powder for Suspension 250 mg/5 ml treat skin infections?

Yes, it is used for bacterial skin infections.

32. Can Sefin DS Powder for Suspension 250 mg/5 ml cause stomach pain?

Yes, mild stomach discomfort is a common side effect.

33. How should Sefin DS Powder for Suspension 250 mg/5 ml be stored?

Store at room temperature, away from moisture and heat.

34. Does Sefin DS Powder for Suspension 250 mg/5 ml cause yeast infections?

Yes, prolonged use may lead to yeast infections.

35. Can Sefin DS Powder for Suspension 250 mg/5 ml cause headaches?

Headaches are a possible but uncommon side effect.

36. Can Sefin DS Powder for Suspension 250 mg/5 ml be given intravenously?

No, Sefin DS Powder for Suspension 250 mg/5 ml is usually taken orally or via injection.

37. Can Sefin DS Powder for Suspension 250 mg/5 ml be used for food poisoning?

Only if caused by susceptible bacteria, not for viral food poisoning.

38. Can Sefin DS Powder for Suspension 250 mg/5 ml be taken long-term?

No, it is meant for short-term use only.

39. Does Sefin DS Powder for Suspension 250 mg/5 ml affect birth control pills?

It may reduce their effectiveness. Use additional contraception.

40. Can Sefin DS Powder for Suspension 250 mg/5 ml cause dizziness?

Dizziness is an uncommon but possible side effect.

41. Is Sefin DS Powder for Suspension 250 mg/5 ml safe for elderly patients?

Yes, but kidney function should be monitored.

42. Can Sefin DS Powder for Suspension 250 mg/5 ml treat bronchitis?

Yes, it is sometimes prescribed for bacterial bronchitis.

43. Can Sefin DS Powder for Suspension 250 mg/5 ml cause liver damage?

Rarely, but liver function should be monitored in long-term use.

44. Can Sefin DS Powder for Suspension 250 mg/5 ml be used for gonorrhea?

No, other antibiotics like ceftriaxone are preferred.

45. Does Sefin DS Powder for Suspension 250 mg/5 ml cause sun sensitivity?

Sun sensitivity is not a common side effect.

46. Can Sefin DS Powder for Suspension 250 mg/5 ml treat typhoid fever?

No, other antibiotics like ciprofloxacin are preferred.

47. Can Sefin DS Powder for Suspension 250 mg/5 ml cause weight loss?

Weight loss is not a common side effect.

48. Can I take Sefin DS Powder for Suspension 250 mg/5 ml if I have diabetes?

Yes, but monitor blood sugar levels as some antibiotics may affect them.

49. Can Sefin DS Powder for Suspension 250 mg/5 ml be used for sinus infections?

Yes, it is sometimes prescribed for bacterial sinus infections.

50. How long should I take Sefin DS Powder for Suspension 250 mg/5 ml?

Take it for the full duration prescribed by your doctor.

Medical review

Last reviewed: 24 Jul 2026

Medically reviewed by:

This is general information, not personal medical advice. Consult a doctor before taking any medicine.

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Dr. Uttom Kumar Shet

Dr. Uttom Kumar Shet

Dental Implant Specialist and Course Director (Osstem Implant), Maxillofacial Surgery

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Dr. Md. Omar Faruk

Dr. Md. Omar Faruk

Medicine & Diabetes Specialist

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Dr. Hasan Zahid

Dr. Hasan Zahid

Newborn & Child Diseases Specialist

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