Brand Name Roxcin
Type Tablet
Weight 300 mg
Generic Roxithromycin
Manufacturer Alco Pharma Ltd.
Price Unit: ৳ 14.04 (20s pack: ৳ 280.80)

About Roxcin

Roxcin Tablet (Alco Pharma Ltd.) is a brand medicine containing the generic Roxithromycin . Current listed price in Bangladesh: Unit: ৳ 14.04 (20s pack: ৳ 280.80).

Medical information for Roxcin Tablet 300 mg

Uses, dosage, side effects, and safety details below apply to Roxcin Tablet 300 mg (generic: Roxithromycin). This is general information — consult a doctor before use.

Introduction

Roxcin Tablet 300 mg is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin. It was shown to be more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. Roxcin Tablet 300 mg exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis.

Uses

Roxcin Tablet 300 mg is an antibiotic used to treat a variety of susceptible bacterial infections.

Used to treat respiratory tract, urinary and soft tissue infections.

Associated Conditions

  • Lower Respiratory Tract and Lung Infections
  • Respiratory Tract Infections (RTI)
  • Skin Infections
  • Ear
  • nose
  • and throat infections

Pharmacodynamics

Roxcin Tablet 300 mg has the following antibacterial spectrum in vitro: Streptococcus agalactiae, Streptococcus pneumoniae (Pneumococcus), Neisseria meningitides (Meningococcus), Listeria monocytogenes, Mycoplasma pneumoniae, Chlamydia trachomatis, Ureaplasma urealyticum, Legionella pneumophila, Helicobacter (Campylobacter), Gardnerella vaginalis, Bordetella pertussis, Moraxella catarrhalis (Branhamella Catarrhalis), and Haemophilus ducreyi. Roxcin Tablet 300 mg is highly concentrated in polymorphonuclear leukocytes and macrophages, achieving intracellular concentrations greater than those outside the cell. Roxcin Tablet 300 mg enhances the adhesive and chemotactic functions of these cells which in the presence of infection produce phagocytosis and bacterial lysis. Roxcin Tablet 300 mg also possesses intracellular bactericidal activity.

Mechanism of Action

Roxcin Tablet 300 mg prevents bacterial growth by interfering with their protein synthesis. It binds to the 50S subunit of bacterial ribosomes and inhibits the translocation of peptides.

Absorption

Very rapidly absorbed and diffused into most tissues and phagocytes.

Protein Binding

96%, mainly to alpha1-acid glycoproteins

Half Life

12 hours

Toxicity

Roxcin Tablet 300 mg primarily causes gastrointestinal adverse events, such as diarrhoea, nausea, abdominal pain and vomiting. Less common adverse events include headaches, rashes, abnormal liver function values and alteration in senses of smell and taste.

Dosage

Adult dose: The usual dose for adults is one 300 mg tablet once daily or one 150 mg tablet twice a day for at least two days after resolution of symptoms, a normal course of therapy is between 5 and 10 days. Roxcin Tablet 300 mg is best administered on empty stomach. In severe hepatic impairment the dose is 150 mg once daily.

Pediatric dose: The dose for children is 2.5 to 5 mg/kg body weight twice a day. The following general guidelines can be followed
  • 6 to 11 Kg: 25 mg Roxcin Tablet 300 mg 12 hourly.
  • 12 to 23 Kg: 50 mg Roxcin Tablet 300 mg 12 hourly.
  • 24 to 40 Kg: 100 mg Roxcin Tablet 300 mg 12 hourly.
A normal course of therapy is between 5 and 10 days.

Frequently Asked Questions About Roxcin Tablet 300 mg

1. What is Roxcin Tablet 300 mg?

Roxcin Tablet 300 mg is an antibiotic belonging to the macrolide class. It is used to treat bacterial infections by inhibiting the growth of bacteria.

2. What type of infections does Roxcin Tablet 300 mg treat?

Roxcin Tablet 300 mg is commonly used to treat respiratory tract infections, skin infections, ear infections, and certain types of bacterial throat infections.

3. How does Roxcin Tablet 300 mg work?

Roxcin Tablet 300 mg works by inhibiting bacterial protein synthesis, preventing bacteria from multiplying and helping to eliminate the infection.

4. How is Roxcin Tablet 300 mg taken?

Roxcin Tablet 300 mg is usually taken orally, either in tablet form or as a suspension. It is typically taken once or twice a day, with or without food.

5. What is the usual dosage of Roxcin Tablet 300 mg?

The usual dosage of Roxcin Tablet 300 mg is 150 mg to 300 mg per day, depending on the type and severity of the infection. Always follow the dosage prescribed by your doctor.

6. Can Roxcin Tablet 300 mg be used for sore throat?

Yes, Roxcin Tablet 300 mg can be used to treat bacterial throat infections, including sore throat caused by Streptococcus bacteria.

7. Can Roxcin Tablet 300 mg treat pneumonia?

Yes, Roxcin Tablet 300 mg is effective in treating pneumonia, especially bacterial pneumonia caused by susceptible organisms.

8. Can I drink alcohol while taking Roxcin Tablet 300 mg?

It is best to avoid alcohol while taking Roxcin Tablet 300 mg, as it may increase the risk of side effects like stomach upset or dizziness.

9. How long should I take Roxcin Tablet 300 mg?

The duration of treatment depends on the infection being treated. Typically, Roxcin Tablet 300 mg is taken for 5 to 10 days, but your doctor will provide specific instructions.

10. What are the common side effects of Roxcin Tablet 300 mg?

Common side effects of Roxcin Tablet 300 mg include:

  • Stomach upset
  • Diarrhea
  • Nausea
  • Headache

11. Can Roxcin Tablet 300 mg cause an allergic reaction?

Yes, although rare, some people may experience allergic reactions to Roxcin Tablet 300 mg, including rashes, itching, and difficulty breathing. Seek medical attention if you experience these symptoms.

12. Can Roxcin Tablet 300 mg be used for ear infections?

Yes, Roxcin Tablet 300 mg is often prescribed for ear infections (otitis media) caused by susceptible bacteria.

13. Can Roxcin Tablet 300 mg be used for skin infections?

Yes, Roxcin Tablet 300 mg can treat certain skin infections like impetigo or cellulitis caused by bacteria.

14. Can Roxcin Tablet 300 mg be taken during pregnancy?

Roxcin Tablet 300 mg should only be used during pregnancy if prescribed by a doctor. It is classified as a pregnancy category C drug, meaning the risks and benefits should be evaluated by a healthcare provider.

15. Is Roxcin Tablet 300 mg safe for children?

Yes, Roxcin Tablet 300 mg can be prescribed to children, but the dosage is based on the child's age and weight. Always consult a pediatrician before giving this medication to a child.

16. Can Roxcin Tablet 300 mg be used for a cold or the flu?

No, Roxcin Tablet 300 mg is not effective against viral infections like the common cold or flu. It only works against bacterial infections.

17. What should I do if I miss a dose of Roxcin Tablet 300 mg?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.

18. Can Roxcin Tablet 300 mg be taken with other medications?

Roxcin Tablet 300 mg can interact with other medications, such as certain antihistamines, blood thinners, and antifungals. Always inform your doctor about all the medications you are taking.

19. Can I stop taking Roxcin Tablet 300 mg once I feel better?

No, you should complete the full course of treatment, even if you start feeling better. Stopping the medication early can lead to the infection returning or developing antibiotic resistance.

20. Can Roxcin Tablet 300 mg cause stomach upset?

Yes, stomach upset, including nausea, vomiting, and diarrhea, is a common side effect of Roxcin Tablet 300 mg. Taking the medication with food may help reduce these symptoms.

21. Can Roxcin Tablet 300 mg be used for bronchitis?

Yes, Roxcin Tablet 300 mg can be used to treat bacterial bronchitis, especially when the infection is caused by susceptible bacteria.

22. Can Roxcin Tablet 300 mg interact with grapefruit?

Yes, grapefruit can interfere with the metabolism of Roxcin Tablet 300 mg and increase the risk of side effects. It is best to avoid grapefruit while taking this medication.

23. How should I store Roxcin Tablet 300 mg?

Store Roxcin Tablet 300 mg in a cool, dry place, away from heat and moisture. Keep it out of reach of children.

24. What should I do if I overdose on Roxcin Tablet 300 mg?

If you suspect an overdose, seek immediate medical attention. Symptoms of an overdose may include severe stomach pain, vomiting, and diarrhea.

25. Can Roxcin Tablet 300 mg cause liver problems?

In rare cases, Roxcin Tablet 300 mg may cause liver damage, leading to symptoms like yellowing of the skin or eyes. If you experience these symptoms, contact your doctor immediately.

26. Can Roxcin Tablet 300 mg treat strep throat?

Yes, Roxcin Tablet 300 mg can be used to treat strep throat caused by Streptococcus bacteria, especially in patients who are allergic to penicillin.

27. Does Roxcin Tablet 300 mg cause dizziness?

Roxcin Tablet 300 mg may cause dizziness or lightheadedness, particularly if you are dehydrated or taking other medications. Avoid driving if you feel dizzy.

28. Can I use Roxcin Tablet 300 mg for a sinus infection?

Yes, Roxcin Tablet 300 mg may be prescribed for bacterial sinus infections, especially if the infection is caused by susceptible bacteria.

29. Can Roxcin Tablet 300 mg be used for tuberculosis (TB)?

No, Roxcin Tablet 300 mg is not used to treat tuberculosis. Specific antibiotics are required to treat TB, and a healthcare provider will prescribe the appropriate treatment.

30. What are the contraindications of Roxcin Tablet 300 mg?

Roxcin Tablet 300 mg should not be used in patients with a history of allergic reactions to macrolide antibiotics or certain other conditions. Always consult your doctor before starting treatment.

31. Can Roxcin Tablet 300 mg be taken with food?

Yes, Roxcin Tablet 300 mg can be taken with or without food. However, taking it with food may help reduce stomach upset.

32. Can Roxcin Tablet 300 mg cause skin rashes?

Yes, skin rashes are a possible side effect of Roxcin Tablet 300 mg. If you develop a rash, consult your doctor for further evaluation.

33. How does Roxcin Tablet 300 mg compare to other antibiotics?

Roxcin Tablet 300 mg is a macrolide antibiotic and works similarly to other antibiotics in its class, such as azithromycin and clarithromycin. However, each antibiotic may have different effectiveness against certain bacteria.

34. Can Roxcin Tablet 300 mg be used for UTI (Urinary Tract Infection)?

Roxcin Tablet 300 mg is not the first-line treatment for urinary tract infections, but it may be used if the infection is caused by susceptible bacteria.

35. Is Roxcin Tablet 300 mg effective against resistant bacteria?

Roxcin Tablet 300 mg is effective against many common bacteria but may not work against resistant strains. Your healthcare provider may prescribe a different antibiotic if resistance is suspected.

36. Can I take Roxcin Tablet 300 mg if I have kidney problems?

If you have kidney problems, consult your doctor before using Roxcin Tablet 300 mg. They may need to adjust the dosage or monitor you closely for side effects.

37. Can Roxcin Tablet 300 mg be used for acne?

Roxcin Tablet 300 mg is sometimes used to treat acne caused by bacterial infections, particularly in patients who do not respond to other treatments.

38. Can I use Roxcin Tablet 300 mg if I have a history of heart disease?

Consult your healthcare provider if you have a history of heart disease. Macrolide antibiotics like Roxcin Tablet 300 mg may increase the risk of heart problems in some patients.

39. Can I take Roxcin Tablet 300 mg with other antibiotics?

Roxcin Tablet 300 mg may interact with certain antibiotics. Always inform your healthcare provider about other medications you are taking to avoid potential drug interactions.

40. How soon will I feel better after starting Roxcin Tablet 300 mg?

Most patients start to feel better within a few days of starting treatment, but it is important to complete the full course of antibiotics as prescribed.

41. Can Roxcin Tablet 300 mg be used to treat dental infections?

Yes, Roxcin Tablet 300 mg can be used to treat certain dental infections caused by susceptible bacteria.

42. Can Roxcin Tablet 300 mg cause gastrointestinal problems?

Gastrointestinal issues, such as diarrhea and nausea, are common side effects of Roxcin Tablet 300 mg. If these symptoms are severe, consult your doctor.

43. Can I use Roxcin Tablet 300 mg for bacterial conjunctivitis?

Roxcin Tablet 300 mg may be used to treat bacterial conjunctivitis, though topical antibiotics are typically preferred for eye infections.

44. Can Roxcin Tablet 300 mg cause drowsiness?

Roxcin Tablet 300 mg does not typically cause drowsiness, but some individuals may feel fatigued as a side effect. Always use caution when performing tasks that require alertness.

45. Can Roxcin Tablet 300 mg be used for viral infections?

No, Roxcin Tablet 300 mg is not effective against viral infections like the flu or cold. It is only used for bacterial infections.

46. What are the signs of a Roxcin Tablet 300 mg overdose?

Signs of an overdose may include severe nausea, vomiting, and diarrhea. If you suspect an overdose, seek medical attention immediately.

47. Can I take Roxcin Tablet 300 mg if I have liver disease?

If you have liver disease, consult your doctor before using Roxcin Tablet 300 mg. Your doctor may need to adjust your dosage or monitor you more closely.

48. Is Roxcin Tablet 300 mg available over the counter?

No, Roxcin Tablet 300 mg is a prescription medication and should be taken only under the guidance of a healthcare provider.

49. Can I take Roxcin Tablet 300 mg while breastfeeding?

Consult your doctor before taking Roxcin Tablet 300 mg while breastfeeding, as it can pass into breast milk.

Medical review

Last reviewed: 24 Jul 2026

Medically reviewed by:

This is general information, not personal medical advice. Consult a doctor before taking any medicine.

Taking medicines without doctor's advice can cause long-term problems.
Dr. Arif Mahmud Jewel

Dr. Arif Mahmud Jewel

Ear, Nose, Throat Specialist & Head Neck Surgeon

Call Doctor
Dr. Mohammad Ashikur Rahman Khan

Dr. Mohammad Ashikur Rahman Khan

KIdney, Medicine & Diabetes Specialist

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