Prostam Capsule (Modified Release)

Prostam Capsule (Modified Release) 0.4 mg

Tamsulosin hydrochloride (Flomax) is a commonly prescribed medication used in the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). It is an alpha-blocker that works by relaxing the muscles in the prostate and bladder neck, allowing urine to flow more freely and decreasing the urinary symptoms that men may experience.

Uses For

Tamsulosin hydrochloride is used to treat the symptoms of benign prostatic hyperplasia (BPH), a condition in which the prostate gland enlarges, pressing against the urethra and causing difficulty in urinating. Symptoms of BPH can include feeling the urge to urinate often, difficulty emptying the bladder, and often waking up during the night to urinate. Tamsulosin hydrochloride can help to reduce these symptoms and improve urination flow.

Brand Name	Prostam
Type	Capsule (Modified Release)
Weight	0.4 mg
Generic	Tamsulosin Hydrochloride
Manufacturer	Drug International Ltd.
Available in	English বাংলা

Mechanism of Action

Tamsulosin hydrochloride works by selective inhibition of the alpha-1A and alpha-1D receptors in muscles of the prostate, bladder neck, and urethra. This in turn relaxes the muscles in those areas, allowing urine to flow more freely and relieving symptoms of BPH.

How Long Does It Take to Work?

The effects of tamsulosin hydrochloride usually begin within a few days of taking the medication, and may take a few weeks or months to reach full effect. It is important to take tamsulosin hydrochloride regularly in order to experience its maximum benefit.

Absorption

Tamsulosin hydrochloride is rapidly and extensively absorbed after oral administration; peak plasma concentrations occur approximately 1 hour after dosing.

Route of Elimination

Tamsulosin hydrochloride is mainly eliminated via the kidney. It is metabolized by the liver and has an elimination half-life of about 7 hours.

Dosage

The recommended starting dose of tamsulosin hydrochloride is 0.4 mg once daily. It is not recommended to take more than 0.8 mg per day. This medication should be taken after a meal and should be taken at the same time each day. Make sure to talk to your doctor about the right dosage for your particular condition.

Administration

Tamsulosin hydrochloride can be taken with or without food and with a full glass of water. It should be taken at the same time each day to maximize the benefits.

Side Effect

The most common side effects of tamsulosin hydrochloride include headache, dizziness, fatigue, and difficulty sleeping. Less common side effects may include sore throat, stuffy nose, indigestion, and nausea. If any of these side effects become severe or don't go away, contact your doctor.

Toxicity

Tamsulosin hydrochloride is generally well tolerated and is not expected to pose a risk of toxicity. Overdose of this medication may cause dizziness, fatigue, difficulty sleeping, and headache. If an overdose is suspected, seek medical attention immediately.

Precaution

Before taking tamsulosin hydrochloride, talk to your doctor if you have kidney or liver disease, heart disease, or any type of bleeding or clotting disorder. If you experience any dizziness or lightheadedness while taking this medication, contact your doctor right away. You should not take tamsulosin hydrochloride if you are also taking certain medications such as nitrates, certain diuretics, calcium channel blockers, or alpha blockers.

Interaction

Tamsulosin hydrochloride may interact with certain medications, including certain medications used to treat high blood pressure, certain antibiotics and HIV protease inhibitors. It is important to tell your healthcare provider about all the medications you are taking, including over-the-counter medications and supplements.

Disease Interaction

Tamsulosin hydrochloride may interact with certain diseases, including renal impairment and prostate cancer. It is important to discuss your medical history with your doctor before taking this medication.

Drug Interaction

Tamsulosin hydrochloride may interact with certain drugs, including some high blood pressure medications, certain antibiotics, and certain HIV protease inhibitors. Make sure to tell your healthcare provider about all the medications you are taking before starting tamsulosin hydrochloride.

Food Interactions

There are no known food interactions with tamsulosin hydrochloride. It is generally recommended to take this medication with food or right after a meal.

Pregnancy Use

Tamsulosin hydrochloride is not recommended for use during pregnancy. It is important to discuss your medical history with your doctor before taking this medication if you are pregnant or planning to become pregnant.

Lactationuse

Tamsulosin hydrochloride is not recommended for use during lactation. It is important to discuss your medical history with your doctor before taking this medication if you are breastfeeding.

Acute Overdose

Symptoms of an overdose of tamsulosin hydrochloride may include dizziness, fatigue, difficulty sleeping, and headache. If an overdose is suspected, seek medical attention immediately.

Contraindications

Tamsulosin hydrochloride is contraindicated in patients with a known hypersensitivity to any component of the drug. It is also not recommended for use in combination with other alpha blockers, nitrate, or calcium channel blockers.

Use Direction

Tamsulosin hydrochloride should be taken once daily with or without food. Take it at the same time every day. Do not take more than the recommended dose or take it more often than prescribed.

Storage Condition

Tamsulosin hydrochloride should be stored at room temperature (15-30°C) away from light and keep in the original package. Do not expose to moisture or heat.