Novas Tablet

Introduction

Novas Tablet 500 mg is an over-the-counter nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with arthritis and other conditions. It is available under different brand names and concentrations. Novas Tablet 500 mg is also used to reduce fever and treat menstrual pain.

Uses for

Novas Tablet 500 mg is used for the treatment of mild to moderate pain, inflammation, and fever associated with arthritis, tendinitis, bursitis, menstrual pain, gout, headache, back pain, and other muscular and joint conditions. It can also be used for other conditions such as reducing fever, premenstrual syndrome, and relieving the symptoms of common colds.

Brand Name	Novas
Type	Tablet
Weight	500 mg
Generic	Naproxen Sodium
Manufacturer	Maks Drug Limited
Available in	English বাংলা

Mechanism of Action

Novas Tablet 500 mg is a strong nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of certain chemicals in the body which are responsible for inflammation, pain, and fever. It also reduces swelling and inflammation, and can help to decrease the frequency of headaches or other pains.

How Long Does It Take to Work?

The effects of Novas Tablet 500 mg can be felt within a short time after taking it, usually 20 to 30 minutes. However, maximum effects may not be seen for up to two hours.

Absorption

Novas Tablet 500 mg is quickly absorbed from the GI tract, with peak serum concentrations of naproxen observed after 2 to 4 hours. Its bioavailability is estimated to be around 85%.

Route of Elimination

Novas Tablet 500 mg is metabolized in the liver and primarily excreted as metabolites in the urine and feces. It has an elimination half-life of 13 to 17 hours.

Dosage

Naproxen oral preparations should be taken with water preferably after meals.

Naproxen Enteric Coated Tablet: Adult:

For rheumatoid arthritis/ osteoarthritis/ ankylosing spondylitis: For adults 500-1000 mg per day taken in two devided doses at 12- hour intervals. The maintenance dose is usually 500 mg per day taken in two devided doses at 12 - hour intervals. The total daily dose of Naproxen should not exceed 1000 mg maintaining 12-hour intervals.
For acute gout: 750 mg should be given initially, then 250 mg every 8 hours until the attack has passed. Children under 16 years are not recommended.
For dysmenorrhoea: For adults 500 mg should be given initially, followed by 250 mg at 6-8 hour intervals for upto 5 days, if necessary.
For other indications like analgesia and acute musculoskeletal disorders: 500 mg should be given initially, followed by 250 mg at 6-8 hour intervals, if necessary.

Naproxen Enteric Coated Tablet: Children: Children under 16 years are not recommended.

Naproxen Suspension: Children:

For juvenile rheumatoid arthritis: The usual dose for children over 2 years is 10 mg/kg/day given as two divided doses at 12-hour intervals. Therapy in children under 2 years of age is not recommended. The following may be used as a guide for dosage of suspension:

13 kg (29 lb) 2.5 mL b.i.d.
25 kg (55 lb) 5 mL b.i.d.
38 kg (84 lb) 7.5 mL b.i.d.

Naproxen Gel: Is to be applied 2-6 times a day as required and is not recommended for use in children. The dosage of Novas Tablet 500 mg depends on the severity of the condition being treated and the patient's response to the medication. It is available as a tablet or oral suspension, and should be taken with food or milk to reduce stomach irritation. • Tablets: The usual prescribed dose is 250 to 500 mg taken two to three times a day. • Oral Suspension: The usual prescribed dose is 5 to 10 mL taken two to three times a day.

Administration

Novas Tablet 500 mg should be taken as directed by the doctor or healthcare provider. It is usually taken with a full glass of water or other liquid to reduce stomach irritation. It should be taken with food or milk. Do not lie down within 10 to 15 minutes after taking it.

Side Effect

The side effects associated with Novas Tablet 500 mg may include: nausea, vomiting, stomach pain, gas, dizziness, headache, rash, itching and upset stomach. Long-term use of this medication may result in increased risk of kidney or liver damage and high blood pressure.

Toxicity

The most common adverse effects of Novas Tablet 500 mg include nausea, heartburn, headaches, abdominal pain, constipation, diarrhea, indigestion, and dizziness. Overdose of Novas Tablet 500 mg can lead to severe toxicity affecting many organs. Symptoms of overdose may include liver damage, increased blood pressure, kidney damage, confusion, and coma.

Precaution

Novas Tablet 500 mg should be used with caution in those with liver or kidney disease, hypertension, asthma, heart failure, bleeding disorders, and in the elderly. It should be avoided in women who are pregnant or breastfeeding. The medication should always be taken with food in order to minimize stomach irritation.

Interaction

Novas Tablet 500 mg may interact with several drugs, including other NSAIDs, anticoagulants, diuretics, corticosteroids, methotrexate, probenecid, and other medications used to treat pain, inflammation, or fever. It should be used with caution in those taking other medications, and patients should tell their doctor if they are taking any other medications before taking Novas Tablet 500 mg.

Disease Interaction

Novas Tablet 500 mg may interact with certain medical conditions, such as asthma, ulcerative colitis, heart disease, kidney or liver disease, and high blood pressure. People with certain allergies or any of these conditions should inform their doctor before taking the medication.

Drug Interaction

Novas Tablet 500 mg may interact with certain drugs, such as anticoagulants, diuretics, corticosteroids, methotrexate, probenecid, and other medications used to treat pain, inflammation, or fever. It should be used with caution in those taking other medications, and patients should tell their doctor if they are taking any other medications before taking Novas Tablet 500 mg.

Food Interaction

Novas Tablet 500 mg may interact with certain food and beverage items, such as alcohol, caffeine, and grapefruit. The effects of these substances on Novas Tablet 500 mg may be significantly increased when consumed together.

Pregnancy Use

Novas Tablet 500 mg should not be taken by pregnant women except on the advice of a doctor. The effects of naproxen on a developing fetus have not been fully studied.

Lactation Use

Novas Tablet 500 mg should not be taken by breastfeeding mothers except on the advice of a doctor. It is not known if Novas Tablet 500 mg passes into breast milk, and its effects on a nursing baby are not known.

Acute Overdose

Symptoms of acute overdose include nausea, vomiting, abdominal pain, tachycardia, drowsiness, confusion, increased blood pressure, confusion, weakness, coma, and death. Treatment of acute overdose includes supportive care and administration of activated charcoal and other drugs as needed.

Contraindication

Novas Tablet 500 mg should not be taken by people who are allergic to NSAIDs or any of the components of the medication. It should also be avoided in people with active bleeding disorders or those taking anticoagulants.

Use Direction

Novas Tablet 500 mg should always be taken as directed by a doctor or healthcare provider. It should be taken with food or milk in order to reduce stomach irritation. Do not lie down within 10 to 15 minutes after taking it.

Storage Condition

Novas Tablet 500 mg tablets should be stored in a cool, dry place and away from light. The oral suspension should be stored in the refrigerator and discarded after 10 days.