Mometasone furoate is a topical corticosteroid belonging to the class of corticosteroids known as glucocorticoids, which are used to treat a variety of inflammatory conditions including eczema, psoriasis, allergies, and asthma.
Mometasone furoate is used to treat various skin conditions such as eczema, psoriasis, allergies or inflammation caused by infections. Additionally, mometasone furoate is also used as an inhalant for asthma control.
| Brand Name | Metaspray |
|---|---|
| Type | Nasal Spray |
| Weight | 50 mcg/spray |
| Generic | Mometasone Furoate |
| Manufacturer | Square Pharmaceuticals Ltd. |
| Available in | English বাংলা |
Mometasone furoate acts by binding to glucocorticoid receptors in the skin and reducing the production of inflammatory chemicals which cause the inflammation, redness, itching and swelling associated with eczema and other skin conditions.
Generally, mometasone furoate products will begin to work within 24 to 48 hours of application, with symptoms such as redness and itching reducing significantly. However, it may take up to two weeks for a full course of treatment to complete.
Mometasone furoate is readily absorbed through intact human skin, with peak concentrations occurring between 1 and 24 hours after topical application. The efficacy of treatment with mometasone is increased when it is applied to skin that is inflamed from the conditions it is intended to treat.
Mometasone furoate is eliminated from the body mainly in urine and feces. The elimination half-life of mometasone is approximately 12 hours.
Mometasone furoate topical solution is available in 0.1 and 0.2% concentrations and is supplied in 15mL and 30mL containers, respectively. The 0.1% solution is usually applied to the affected area twice daily whereas the 0.2% solution is usually applied once daily.
Mometasone furoate topical solution is applied topically by first washing the area with a mild cleanser and then drying with a towel. The product is then applied to the affected area by using a clean finger or cotton applicator to gently spread a thin film over the area.
Common side effects associated with mometasone furoate topical solutions include dryness, burning, stinging, and redness of the skin; these effects are usually mild and transient. Additionally, mometasone furoate can cause serious side effects such as increased skin irritation, skin thinning, and stretch marks.
Mometasone furoate is generally well tolerated when applied topically and is not associated with significant toxicity. However, contact allergy can occur in some individuals and cause severe irritation, redness, and itching.
Mometasone furoate topical solutions should not be used on large areas of skin, irritated areas of skin, or for prolonged durations without first consulting with a doctor. Additionally, it should not be used on the face or genitals, as these areas are more sensitive to the effects of topical steroids. Mometasone furoate should also not be used by individuals who are allergic to corticosteroids.
Mometasone furoate may interact with other drugs and should be used with caution when taking other medications such as antifungals, antibiotics, antihistamines, and acne treatments. In addition, mometasone furoate may interact with topical products containing alcohol, sodiu,m or salicylic acid.
Mometasone furoate may interact with certain diseases such as rosacea, diabetes, and thyroid diseases. It should be used with caution in people with these diseases.
Mometasone furoate may interact with certain drugs, such as blood pressure medications, antifungal medications, antibiotics, and certain antidepressants. It is important to consult with a doctor before using mometasone furoate if taking any of these medications.
Mometasone furoate does not interact with food, however, it is important to check with a doctor before taking any medications with mometasone furoate.
Mometasone furoate is not recommended for pregnant women and should be avoided during pregnancy. It is important to consult with a doctor before using mometasone furoate if pregnant or planning on becoming pregnant.
Mometasone furoate is not recommended for lactating women and should be avoided during lactation. It is important to consult with a doctor before using mometasone furoate if breastfeeding or planning on breastfeeding.
There is no known antidote to an acute mometasone furoate overdose, however, it is important to discontinue use and seek immediate medical attention in case of an overdose.
Mometasone furoate is contraindicated in individuals with known hypersensitivity to mometasone furoate or any of the other ingredients in the particular product. Additionally, mometasone furoate should not be applied to broken skin, infected areas, or areas of skin with other skin infections.
Mometasone furoate topical solution should be used as directed by a doctor. It is important to use the product exactly as directed in order to reduce the risk of side effects.
Mometasone furoate topical solution should be stored at room temperature, away from heat and light. It should be kept in a tightly closed container at a temperature between 15 and 30 degrees C (59 and 86 degrees F).
Mometasone furoate has a volume of distribution of 14.1 L/kg.
The half life of mometasone furoate is approximately 12 hours.
The clearance of mometasone furoate is 0.88 L/min/kg.
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