Introduction

Leventa Syrup 1 mg/5 ml is a β-agonist bronchodilator used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It is a long-acting β-adrenergic agonist (LABA) that is an active isomer of albuterol, which belongs to a family of drugs called sympathomimetics. Leventa Syrup 1 mg/5 ml helps to relax the muscles in the airways, which helps widen the airways resulting in decreased airway obstruction.

Uses

Leventa Syrup 1 mg/5 ml is used in the long-term management of asthma and COPD to improve air flow to the lungs. It is also used to prevent exercise-induced bronchospasm (EIB) in people with asthma, and to treat wheezing, shortness of breath, and other symptoms of airway obstruction in people with COPD.

Mechanism of action

Leventa Syrup 1 mg/5 ml works by stimulating β-adrenergic receptors on airway smooth muscle. This causes relaxation of the airways and improved airflow.

How long does it take to work?

Leventa Syrup 1 mg/5 ml begins to work within minutes of inhalation, with peak therapeutic effect at approximately 30 minutes.

Absorption

The absorption of levalbutamol is rapid and the drug is completely absorbed within 10 minutes after inhalation.

Route of elimination

Leventa Syrup 1 mg/5 ml is eliminated primarily through metabolic processes in the liver.

Dosage

The recommended dose of levalbutamol is 200 mcg twice daily for adults and adolescents with asthma, and 500 mcg twice daily for adults and adolescents with COPD.

Administration

Leventa Syrup 1 mg/5 ml is available as an inhaler, and should be inhaled directly into the mouth, or with a spacer device.

Side effects

The most common side effects of levalbutamol are headache, throat irritation, nausea, and dizziness.

Toxicity

Acute overdose of levalbutamol can result in restlessness, palpitations, and increased blood pressure, heart rate, and respiratory rate.

Precaution

Leventa Syrup 1 mg/5 ml should not be used in people with hypersensitivity to sympathomimetic amines, medical conditions such as severe cardiac arrhythmia, tachycardia, or hypertension, or people with hyperthyroidism or diabetes.

Interaction

Leventa Syrup 1 mg/5 ml may interact with other medications. Tell your doctor all medications and supplements you are taking before using levalbutamol.

Disease Interaction

Leventa Syrup 1 mg/5 ml may interact with certain conditions or diseases. Tell your doctor about any medical conditions you have before using levalbutamol.

Drug Interactions

Leventa Syrup 1 mg/5 ml may interact with other medications. Tell your doctor all medications and supplements you are taking before using levalbutamol.

Food Interactions

Leventa Syrup 1 mg/5 ml does not typically interact with foods. However, people with diabetes should monitor their blood sugar levels more closely while taking levalbutamol.

Pregnancy Use

Leventa Syrup 1 mg/5 ml should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus.

Lactation Use

Leventa Syrup 1 mg/5 ml is excreted in human milk and should be used with caution in lactating women.

Acute Overdose

Symptoms of acute overdose of levalbutamol include restlessness, palpitations, increased blood pressure, heart rate, and respiratory rate. Treatment should be supportive and symptomatic.

Contraindication

Leventa Syrup 1 mg/5 ml should not be used in people with hypersensitivity to sympathomimetic amines, medical conditions such as severe cardiac arrhythmia, tachycardia, or hypertension, or people with hyperthyroidism or diabetes.

Use Directions

Follow the directions for using levalbutamol exactly. Do not use it more often or use more of it than prescribed. Do not stop taking levalbutamol without talking to your doctor first.

Storage Conditions

Store levalbutamol at room temperature, away from direct sunlight, moisture and heat.

Volume of Distribution

The volume of distribution of levalbutamol is 3.2 L/kg.

Half Life

The half-life of levalbutamol is approximately 3-4 hours.

Clearance

The clearance of levalbutamol is approximately 4 mL/min/kg.

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Some Frequently Asked Questions About Leventa Syrup 1 mg/5 ml

1. What is Leventa Syrup 1 mg/5 ml?

Leventa Syrup 1 mg/5 ml (also called Levalbuterol) is a bronchodilator used to treat respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). It helps relax airway muscles and improve breathing.

2. How does Leventa Syrup 1 mg/5 ml work?

Leventa Syrup 1 mg/5 ml selectively stimulates beta-2 adrenergic receptors in the lungs, leading to smooth muscle relaxation and bronchodilation, which helps open up the airways.

3. What conditions is Leventa Syrup 1 mg/5 ml used to treat?

  • Asthma
  • Chronic obstructive pulmonary disease (COPD)
  • Bronchospasm
  • Exercise-induced bronchoconstriction

4. What forms does Leventa Syrup 1 mg/5 ml come in?

  • Inhaler
  • Nebulizer solution
  • Tablet
  • Syrup

5. How should Leventa Syrup 1 mg/5 ml be used?

Leventa Syrup 1 mg/5 ml is usually taken via inhalation using a nebulizer or inhaler. The dosage and frequency depend on the severity of the condition.

6. What is the usual dosage for adults?

  • Inhaler: 90 mcg per puff, 1-2 puffs every 4-6 hours
  • Nebulizer: 0.63 mg or 1.25 mg every 6-8 hours

7. Can Leventa Syrup 1 mg/5 ml be used in children?

Yes, it is prescribed for children, but the dosage is adjusted based on age and weight.

8. What is the difference between Leventa Syrup 1 mg/5 ml and Salbutamol?

Leventa Syrup 1 mg/5 ml is the active "R-enantiomer" of Salbutamol, which is believed to cause fewer side effects like tremors and palpitations while maintaining the same bronchodilation effect.

9. How quickly does Leventa Syrup 1 mg/5 ml work?

It starts working within 5-15 minutes, and its effects last for 4-6 hours.

10. Can Leventa Syrup 1 mg/5 ml be used for an acute asthma attack?

Yes, it is a fast-acting bronchodilator and is used for quick relief during asthma attacks.

11. Can Leventa Syrup 1 mg/5 ml be used for long-term asthma management?

It is mainly a rescue medication. Long-term management usually involves corticosteroids or other controller medications.

12. What are the common side effects of Leventa Syrup 1 mg/5 ml?

  • Tremors
  • Palpitations
  • Nervousness
  • Headache
  • Dizziness

13. Can Leventa Syrup 1 mg/5 ml cause allergic reactions?

Yes, though rare, allergic reactions such as rashes, swelling, and difficulty breathing can occur.

14. Can Leventa Syrup 1 mg/5 ml cause high blood pressure?

It may cause a temporary increase in heart rate and blood pressure, but this is usually mild.

15. What should I do if I miss a dose?

Take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue your schedule.

16. Can I overdose on Leventa Syrup 1 mg/5 ml?

Yes, overdose symptoms include severe tremors, fast heartbeat, chest pain, and seizures. Seek immediate medical help in case of overdose.

17. Can Leventa Syrup 1 mg/5 ml be used for COPD?

Yes, it is often used to relieve symptoms of COPD, such as shortness of breath.

18. Can I use Leventa Syrup 1 mg/5 ml daily?

Yes, but frequent use may indicate poor asthma control, and your doctor may adjust your medication.

19. Can Leventa Syrup 1 mg/5 ml be used with steroids?

Yes, it is often combined with corticosteroids for better asthma and COPD management.

20. Can pregnant women take Leventa Syrup 1 mg/5 ml?

It is used if the benefits outweigh the risks. Consult your doctor before using it during pregnancy.

21. Can Leventa Syrup 1 mg/5 ml be used during breastfeeding?

It can pass into breast milk in small amounts, so consult your doctor before use.

22. Can Leventa Syrup 1 mg/5 ml cause insomnia?

Yes, since it stimulates the nervous system, it may cause trouble sleeping.

23. Is Leventa Syrup 1 mg/5 ml addictive?

No, but overuse can lead to reduced effectiveness over time.

24. Can I drink alcohol while using Leventa Syrup 1 mg/5 ml?

Alcohol may increase side effects like dizziness, so it is best to avoid it.

25. Can Leventa Syrup 1 mg/5 ml be taken with other asthma medications?

Yes, it is often used with inhaled steroids or other long-acting bronchodilators.

26. Can Leventa Syrup 1 mg/5 ml be used for exercise-induced asthma?

Yes, using an inhaler 15-30 minutes before exercise can help prevent asthma symptoms.

27. What should I do if Leventa Syrup 1 mg/5 ml doesn’t work?

Seek medical attention if symptoms persist despite using the prescribed dose.

28. Can Leventa Syrup 1 mg/5 ml be used in nebulizers?

Yes, it is available as a nebulizing solution for inhalation therapy.

29. Does Leventa Syrup 1 mg/5 ml cause weight gain?

No, it does not cause weight gain.

30. Can Leventa Syrup 1 mg/5 ml affect blood sugar levels?

Yes, it may cause temporary increases in blood sugar, especially in diabetics.

31. How should Leventa Syrup 1 mg/5 ml be stored?

Keep it at room temperature, away from moisture and heat.

32. Does Leventa Syrup 1 mg/5 ml interact with beta-blockers?

Yes, beta-blockers like propranolol may reduce its effectiveness.

33. Can children use Leventa Syrup 1 mg/5 ml syrup?

Yes, syrup form is prescribed for young children under a doctor's supervision.

34. How often can I use a Leventa Syrup 1 mg/5 ml inhaler?

Usually every 4-6 hours as needed, but do not exceed the prescribed dose.

35. Can Leventa Syrup 1 mg/5 ml cause chest pain?

Rarely, but if chest pain occurs, seek medical attention immediately.

36. Is Leventa Syrup 1 mg/5 ml a steroid?

No, it is a bronchodilator, not a steroid.

37. Can I use Leventa Syrup 1 mg/5 ml with antibiotics?

Yes, but inform your doctor about all medications you are taking.

38. Can Leventa Syrup 1 mg/5 ml be used for cough?

It is used if the cough is due to bronchospasm.

39. Can Leventa Syrup 1 mg/5 ml be used in heart patients?

Caution is needed as it can increase heart rate.

40. What happens if I stop using Leventa Syrup 1 mg/5 ml suddenly?

Stopping suddenly does not cause withdrawal, but symptoms may return.

41. Can I drive after using Leventa Syrup 1 mg/5 ml?

Yes, unless you experience dizziness or tremors.

42. Can Leventa Syrup 1 mg/5 ml be used for pneumonia?

It may help in pneumonia with bronchospasm but does not treat the infection.

43. Can I take Leventa Syrup 1 mg/5 ml with antihistamines?

Yes, but consult your doctor.

44. Can Leventa Syrup 1 mg/5 ml cause dehydration?

No, but drink plenty of fluids to avoid dry mouth.

45. Is Leventa Syrup 1 mg/5 ml available over-the-counter?

No, it requires a prescription.

46. Can it be used in smokers?

Yes, but smoking worsens lung conditions.

47. Can it cause dizziness?

Yes, dizziness is a common side effect.

48. Can Leventa Syrup 1 mg/5 ml be used in emergencies?

Yes, for acute bronchospasm.

49. Can Leventa Syrup 1 mg/5 ml be used long-term?

It is mainly for short-term relief.

50. Can it be used for allergies?

Only if allergies cause bronchospasm.

*** Taking medicines without doctor's advice can cause long-term problems.
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