Konabiz Shampoo

Introduction

Konabiz Shampoo 2% is a synthetic antifungal medication used to treat a wide variety of fungal infections. It is available as an oral tablet, topical cream, and topical solution, as well as a generic form.

Uses

Konabiz Shampoo 2% is used to treat various fungal infections such as athlete's foot, jock itch, ringworm, and yeast infections of the skin, scalp, mouth, and nails. It is also used to treat fungal infections of the brain and spinal cord caused by Candida (yeast).

Brand Name	Konabiz
Type	Shampoo
Weight	2%
Generic	Ketoconazole
Manufacturer	Health Pro International
Available in	English বাংলা

Mechanism of Action

Konabiz Shampoo 2% inhibits fungal growth by interfering with the fungal cell membrane. It also affects the activity of certain enzymes. These actions stop the spread of the fungal infection.

How Long Does Konabiz Shampoo 2% Take to Work?

Konabiz Shampoo 2% usually begins to work within a few days, depending on the severity and location of the infection. It may take up to several weeks of continuous treatment before infections are completely healed.

Absorption

Konabiz Shampoo 2% can be absorbed either orally or through topical treatments. Oral absorption is rapid, while topical absorption is slower.

Route of Elimination

Konabiz Shampoo 2% is eliminated from the body through bile in the feces and urine.

Dosage

Shampoo: The affected areas of the skin or the scalp should be washed with ketoconazole 2% shampoo, which should be left on the skin/scalp for 3 to 5 minutes before rinsing.

Treatment:

Pityriasis versicolor: Once daily for 5 days.
Seborrhoeic dermatitis and pityriasis capitis: Twice weekly for 2 to 4 weeks.

Prophylaxis:

Pityriasis versicolor: Once daily for 3 days during a single treatment course before the summer.
Seborrhoeic dermatitis and pityriasis capitis: Once every 1 or 2 weeks.

Cream:

Tinea pedis: Ketoconazole cream should be applied to the affected areas twice daily. The usual duration of treatment for mild infections is 1 week. For more severe or extensive infections (e.g. involving the sole or sides of the feet) treatment should be continued until a few days after all signs and symptoms have disappeared in order to prevent relapse.
For other infections: Ketoconazole cream should be applied to the affected areas once or twice daily, depending on the severity of the infection. The treatment should be continued until a few days after the disappearance of all signs and symptoms. The usual duration of treatment is: tinea versicolor 2-3 weeks, tinea corporis 3-4 weeks. The diagnosis should be reconsidered if no clinical improvement is noted after 4 weeks. General measures in regard to hygiene should be observed to control sources of infection or reinfection. Seborrhoeic dermatitis is a chronic condition and relapse is highly likely.

Tablet:

Vaginal candidiasis: 1 tablet (200 mg) tablet twice daily for 5 days.
All other indications: 1 tablet (200 mg) once daily until at least one week after the symptoms have disappeared and the cultures have become negative.

Duration of Treatment-

Pityriasis versicolor: 1 to 6 weeks
Dermatomycoses: 2 to 8 weeks
Onychomycoses: 1 to 12 months
Mycoses of hair and scalp: 1 to 2 months
Chronic mucocutaneous candidiasis : 1 to 12 months
Oral mycoses: 5 to 10 days
Systemic candidiasis: 1 to 2 months
Paracoccidioidomycosis,histoplasmosis
and other systemic mycosis: 1 month to 2 years

Ketoconazole bar: Body Fungus: rub gently on the overall body to produce lather. Leave for 4-5 minutes. Rinse of thoroughly with water. The dosage of ketoconazole depends on the condition being treated and other factors such as age and weight. The dosage can range from 200mg to 400mg taken orally once per day for up to two weeks, or as instructed by your doctor.

Administration

Konabiz Shampoo 2% can be taken orally with or without food. Topical forms of the medication should be applied as instructed by your doctor.

Side Effects

The most common side effects of ketoconazole include nausea, vomiting, diarrhea, stomach pain, headache, and rash. Severe side effects may include liver injury, low blood sugar, and increased risk of fungal infection.

Toxicity

Konabiz Shampoo 2% is generally considered to have low to moderate toxicity. However, in high doses for long periods of time, it can cause liver damage and other adverse effects.

Precautions

Konabiz Shampoo 2% should not be used by people with liver disease, kidney disease, or low blood sugar. It should also not be used by pregnant or nursing women, or people who are taking immunosuppressive drugs.

Interactions

Konabiz Shampoo 2% can interact with other medications and supplements, so it’s important to tell your doctor about all medications and supplements you are taking.

Disease Interactions

Konabiz Shampoo 2% may worsen conditions such as heart disease, diabetes, and kidney disease. It can also interact negatively with medications used to treat these conditions.

Drug Interactions

Konabiz Shampoo 2% can interact with other medications, so it’s important to tell your doctor about all medications and supplements you are taking.

Food Interactions

Konabiz Shampoo 2% can interact with certain foods, so it’s important to tell your doctor about all foods and supplements you are taking.

Pregnancy Use

Konabiz Shampoo 2% should not be used during pregnancy, as it can cause harm to the developing baby.

Lactation Use

Konabiz Shampoo 2% is not recommended for use in nursing mothers, as it can pass into breast milk and cause harm to a nursing infant.

Acute Overdose

If an overdose occurs, contact a poison control center immediately. Symptoms of an overdose may include nausea, vomiting, diarrhea, stomach pain, and drowsiness.