Brand Name Isonil
Type Tablet
Weight 5 mg
Generic Oxyphenonium Bromide
Manufacturer Amico Laboratories Ltd.

About Isonil

Isonil Tablet (Amico Laboratories Ltd.) is a brand medicine containing the generic Oxyphenonium Bromide .

Medical information for Isonil Tablet 5 mg

Uses, dosage, side effects, and safety details below apply to Isonil Tablet 5 mg (generic: Oxyphenonium Bromide). This is general information — consult a doctor before use.

Introduction

A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect. [PubChem]

Uses

For the treatment of visceral spasms

Pharmacodynamics

Oxyphenonium is an anticholinergic drug, a medication that reduces the effect of acetylcholine, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle). It also has a direct relaxing effect on smooth muscle. Oxyphenonium is used to treat or prevent spasm in the muscles of the gastrointestinal tract in the irritable bowel syndrome. In addition, Oxyphenonium inhibits gastrointestinal propulsive motility and decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretions.

Mechanism of Action

Action is achieved via a dual mechanism: (1) a specific anticholinergic effect (antimuscarinic) at the acetylcholine-receptor sites and (2) a direct effect upon smooth muscle (musculotropic).

Protein Binding

93% bound to albumin

Dosage

Average adult dosage is 10 mg (2 tablets) 4 times daily for several days. Dosage may be reduced depending on patient's response or as directed by the physician.

Frequently Asked Questions About Isonil Tablet 5 mg

1. What is Isonil Tablet 5 mg?

Isonil Tablet 5 mg is an anticholinergic drug used to treat gastrointestinal disorders, particularly those involving smooth muscle spasms, such as peptic ulcers and irritable bowel syndrome (IBS).

2. How does Isonil Tablet 5 mg work?

Isonil Tablet 5 mg works by blocking the action of acetylcholine, a neurotransmitter that affects smooth muscle contractions, thus reducing spasms and pain in the gastrointestinal tract.

3. What conditions is Isonil Tablet 5 mg used to treat?

Isonil Tablet 5 mg is mainly used for the treatment of gastrointestinal disorders such as peptic ulcers, irritable bowel syndrome (IBS), and certain types of colic.

4. How is Isonil Tablet 5 mg administered?

Isonil Tablet 5 mg is typically administered orally in tablet form. It may also be available in injectable forms for more severe conditions.

5. What is the usual dosage of Isonil Tablet 5 mg?

The typical oral dosage of Isonil Tablet 5 mg is 1-2 tablets taken 2-3 times a day, but your doctor will determine the exact dosage based on your condition.

6. Can Isonil Tablet 5 mg be taken with food?

Yes, Isonil Tablet 5 mg can be taken with or without food. However, taking it with food may help reduce any potential stomach irritation.

7. What are the common side effects of Isonil Tablet 5 mg?

Common side effects of Isonil Tablet 5 mg include:

  • Dry mouth
  • Blurred vision
  • Dizziness
  • Constipation
  • Urinary retention

8. Can Isonil Tablet 5 mg cause allergic reactions?

Yes, allergic reactions to Isonil Tablet 5 mg are possible, including rashes, itching, swelling, or difficulty breathing. Seek immediate medical attention if you experience any of these symptoms.

9. Can Isonil Tablet 5 mg be used for children?

Isonil Tablet 5 mg is generally not recommended for children under 12 years old, unless prescribed by a doctor for specific conditions.

10. Can Isonil Tablet 5 mg be taken during pregnancy?

Isonil Tablet 5 mg should only be used during pregnancy if clearly needed, and the benefits outweigh the risks. Consult your doctor before using this medication while pregnant.

11. Can Isonil Tablet 5 mg be used while breastfeeding?

Isonil Tablet 5 mg is not recommended during breastfeeding, as it may pass into breast milk and affect the infant. Always consult your doctor before taking any medication while breastfeeding.

12. Is Isonil Tablet 5 mg effective for stomach cramps?

Yes, Isonil Tablet 5 mg can be effective in reducing stomach cramps caused by gastrointestinal spasms due to its antispasmodic properties.

13. Can Isonil Tablet 5 mg be used for urinary problems?

Isonil Tablet 5 mg is primarily used for gastrointestinal disorders, but it may also help with urinary retention caused by bladder spasms due to its anticholinergic effects.

14. Can I drink alcohol while taking Isonil Tablet 5 mg?

It is advisable to avoid alcohol while taking Isonil Tablet 5 mg, as alcohol can increase the sedative effects of the medication and cause drowsiness or dizziness.

15. What should I do if I miss a dose of Isonil Tablet 5 mg?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once.

16. What are the contraindications of Isonil Tablet 5 mg?

Isonil Tablet 5 mg should not be used in patients with:

  • Glaucoma
  • Myasthenia gravis
  • Urinary retention
  • Severe gastrointestinal obstruction

17. Can Isonil Tablet 5 mg be used for irritable bowel syndrome (IBS)?

Yes, Isonil Tablet 5 mg is often used to relieve the smooth muscle spasms associated with irritable bowel syndrome (IBS), helping to reduce abdominal pain and discomfort.

18. Can Isonil Tablet 5 mg cause constipation?

Yes, constipation is a common side effect of Isonil Tablet 5 mg due to its anticholinergic properties that can reduce bowel movement frequency.

19. How long should I take Isonil Tablet 5 mg?

The length of treatment with Isonil Tablet 5 mg depends on the condition being treated. Your doctor will determine the appropriate duration of therapy.

20. Can Isonil Tablet 5 mg cause dry mouth?

Yes, dry mouth is a common side effect of Isonil Tablet 5 mg due to its anticholinergic effects. Drinking water or using sugar-free gum may help alleviate this symptom.

21. Is Isonil Tablet 5 mg available over-the-counter?

No, Isonil Tablet 5 mg is a prescription medication and should only be taken under the supervision of a healthcare provider.

22. Can Isonil Tablet 5 mg be used for bloating?

Isonil Tablet 5 mg may help relieve bloating caused by gastrointestinal spasms by reducing the muscle contractions in the digestive tract.

23. Can Isonil Tablet 5 mg interact with other medications?

Yes, Isonil Tablet 5 mg may interact with other medications, including other anticholinergics, antihistamines, and medications for Parkinson's disease. Always inform your doctor of all medications you are taking.

24. How should Isonil Tablet 5 mg be stored?

Store Isonil Tablet 5 mg in a cool, dry place, away from direct sunlight and out of reach of children.

25. Can Isonil Tablet 5 mg cause dizziness?

Yes, dizziness is a possible side effect of Isonil Tablet 5 mg. If you experience dizziness, avoid activities that require full alertness, such as driving or operating heavy machinery.

26. Can I take Isonil Tablet 5 mg for menstrual cramps?

Isonil Tablet 5 mg is not typically used for menstrual cramps, but it may help reduce abdominal pain caused by muscle spasms if prescribed by a doctor.

27. Can Isonil Tablet 5 mg cause blurred vision?

Yes, blurred vision can occur as a side effect due to the drug's anticholinergic properties. This side effect is usually temporary.

28. Can Isonil Tablet 5 mg cause urinary retention?

Yes, Isonil Tablet 5 mg can cause urinary retention due to its effects on smooth muscle function. If you experience difficulty urinating, consult your doctor.

29. Is Isonil Tablet 5 mg safe for long-term use?

Isonil Tablet 5 mg should be used only as prescribed by your doctor. Prolonged use may lead to increased side effects, and regular medical reviews are recommended.

30. How soon will I feel better after taking Isonil Tablet 5 mg?

Most people experience relief from symptoms within a few hours to a day after taking Isonil Tablet 5 mg, but it may vary based on the severity of the condition being treated.

31. Can Isonil Tablet 5 mg be used for indigestion?

Isonil Tablet 5 mg may be useful for indigestion caused by spasms of the gastrointestinal tract, although it is not the first-line treatment for indigestion.

32. Can Isonil Tablet 5 mg cause confusion?

In rare cases, especially in older adults, Isonil Tablet 5 mg may cause confusion, memory problems, or hallucinations. Contact your doctor if these symptoms occur.

33. Can Isonil Tablet 5 mg cause high blood pressure?

Isonil Tablet 5 mg does not typically cause high blood pressure, but it may interact with medications for high blood pressure. Always consult your doctor before taking it if you have hypertension.

34. Can Isonil Tablet 5 mg be taken with other antispasmodic drugs?

Isonil Tablet 5 mg can interact with other antispasmodics, and it is important to consult your doctor before combining medications to avoid excessive side effects.

35. How does Isonil Tablet 5 mg affect the heart?

Isonil Tablet 5 mg can affect the heart rate by causing a slight increase in heart rate. People with heart conditions should use this drug cautiously.

36. Can Isonil Tablet 5 mg affect memory?

Memory problems, such as short-term memory loss, can occur with Isonil Tablet 5 mg, particularly in older adults or with long-term use.

37. Can Isonil Tablet 5 mg cause sweating?

Isonil Tablet 5 mg can reduce sweating in some individuals due to its anticholinergic effects, leading to dry skin and less perspiration.

38. Can Isonil Tablet 5 mg be used for nausea?

Isonil Tablet 5 mg is not typically used for nausea unless it is caused by gastrointestinal spasm. Anti-nausea medications are usually more effective for treating nausea.

39. What should I do if I overdose on Isonil Tablet 5 mg?

If you suspect an overdose of Isonil Tablet 5 mg, seek immediate medical attention. Symptoms may include severe dry mouth, dizziness, and difficulty urinating.

40. Is there a generic version of Isonil Tablet 5 mg?

Yes, Isonil Tablet 5 mg is available in generic versions under various brand names.

41. Can I take Isonil Tablet 5 mg with other anticholinergic medications?

Taking Isonil Tablet 5 mg with other anticholinergic medications may increase the risk of side effects like dry mouth, blurred vision, and urinary retention. Always consult your doctor.

42. Can Isonil Tablet 5 mg be used for gastric ulcers?

Yes, Isonil Tablet 5 mg can be used as part of the treatment for peptic ulcers, as it helps reduce spasms and discomfort in the stomach.

43. Does Isonil Tablet 5 mg interact with antibiotics?

Isonil Tablet 5 mg may interact with certain antibiotics, especially those that affect the gastrointestinal system. Always inform your doctor if you are on antibiotics.

44. Can Isonil Tablet 5 mg be used for acid reflux?

Isonil Tablet 5 mg is not typically used for acid reflux, as it does not address the underlying causes like acid production. Other medications are recommended for acid reflux.

45. Can Isonil Tablet 5 mg be used for abdominal bloating?

Isonil Tablet 5 mg can help relieve bloating caused by smooth muscle spasms in the gastrointestinal tract.

46. What happens if I miss a dose of Isonil Tablet 5 mg?

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double the dose to make up for the missed one.

47. Can Isonil Tablet 5 mg cause dizziness when standing up?

Yes, dizziness upon standing up (orthostatic hypotension) can be a side effect of Isonil Tablet 5 mg. Stand up slowly to avoid feeling lightheaded.

48. Can Isonil Tablet 5 mg affect your skin?

Isonil Tablet 5 mg may cause dry skin and reduced sweating due to its anticholinergic properties.

49. Can Isonil Tablet 5 mg be used for stomach ulcers?

Isonil Tablet 5 mg may be used to treat symptoms of stomach ulcers, such as pain due to smooth muscle spasms, but it is not the primary treatment for ulcer healing.

50. Can Isonil Tablet 5 mg be taken with other GI medications?

Isonil Tablet 5 mg can be taken with other gastrointestinal medications, but interactions should be monitored. Consult your doctor to avoid any potential issues.

Medical review

Last reviewed: 24 Jul 2026

Medically reviewed by:

This is general information, not personal medical advice. Consult a doctor before taking any medicine.

Taking medicines without doctor's advice can cause long-term problems.
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