Dextropac IV Infusion 5% 5% Uses, Dosage, Side Effects & Price - ডেক্সট্রোপ্যাক আইভি ইনফিউশন

Name: Dextropac IV Infusion 5%
Brand: Dextropac
SKU: dextropac-iv-infusion-5-
Price: 50054.88 BDT
Availability: OnlineOnly

Brand Name	Dextropac
Type	IV Infusion
Weight	5%
Generic	Dextrose
Manufacturer	Orion Infusion Ltd.
Price	500 ml bag: ৳ 54.88

Brand Name

Dextropac

Type

IV Infusion

Weight

Generic

Dextrose

Manufacturer

Orion Infusion Ltd.

Price

500 ml bag: ৳ 54.88

About Dextropac

Dextropac IV Infusion (Orion Infusion Ltd.) is a brand medicine containing the generic Dextrose . Current listed price in Bangladesh: 500 ml bag: ৳ 54.88.

Introduction

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines.

Uses

Glucose is a form of glucose used for caloric supply and the replenishment of fluid in total parenteral nutrition and other therapies as well as for the treatment of hypoglycemic episodes.

Glucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used in metabolic disorders such as hypoglycemia.

Associated Conditions

Arrhythmia
Caloric Deficit
Edema of the cerebrum
Metabolic Alkalosis
Hypoglycemic reaction
Blood Specimen Collection
Electrolyte replacement
Nutritional supplementation
Parenteral Nutrition
Parenteral rehydration therapy
Plasmapheresis
Positive cardiac inotropic effect
Total parenteral nutrition therapy
Urine alkalinization therapy
Fluid and electrolyte maintenance therapy

Pharmacodynamics

Blood glucose is an obligatory energy source in humans involved in various cellular activities, and it also acts as a signalling molecule for diverse glucose-sensing molecules and proteins. Glucose undergoes oxidation into carbon dioxide, water and yields energy molecules in the process of glycolysis and subsequent citric cycle and oxidative phosphorylation. Glucose is readily converted into fat in the body which can be used as a source of energy as required. Under a similar conversion into storage of energy, glucose is stored in the liver and muscles as glycogen. Glucose stores are mobilized in a regulated manner, depending on the tissues' metabolic demands. Oral glucose tablets or injections serve to increase the supply of glucose and oral glucose administration is more effective in stimulating insulin secretion because it stimulates the incretin hormones from the gut, which promotes insulin secretion.

Mechanism of Action

Glucose supplies most of the energy to all tissues by generating energy molecules ATP and NADH during a series of metabolism reactions called glycolysis. Glycolysis can be divided into 2 main phases where the preparatory phase is initiated by the phosphorylation of glucose by a hexokinase to form glucose 6-phosphate. The addition of the high-energy phosphate group activates glucose for subsequent breakdown in later steps of glycolysis and is the rate-limiting step. Products end up as substrates for following reactions, to ultimately convert C6 glucose molecule into two C3 sugar molecules. These products enter the energy-releasing phase where total of 4ATP and 2NADH molecules are generated per one glucose molecule. The total aerobic metabolism of glucose can produce up to 36 ATP molecules. This energy-producing reactions of glucose is limited to D-glucose as L-glucose cannot be phosphorlyated by hexokinase. Glucose can act as precursors to generate other biomolecules such as vitamin C. It plays a role as a signaling molecule to control glucose and energy homeostasis. Glucose can regulate gene transcription, enzyme activity, hormone secretion, and the activity of glucoregulatory neurons. The types, number and kinetics of glucose transporters expressed depends on the tissues and fine-tunes glucose uptake, metabolism, and signal generation in order to preserve cellular and whole body metabolic integrity .

Absorption

Polysaccharides can be broken down into smaller units by pancreatic and intestinal glycosidases or intestinal flora. Sodium-dependent glucose transporter SGLT1 and GLUT2 (SLC2A2) play predominant roles in intestinal transport of glucose into the circulation. SGLT1 is located in the apical membrane of the intestinal wall while GLUT2 is located in the basolateral membrane, but it was proposed that GLUT2 can be recruited into the apical membrane after a high luminal glucose bolus allowing bulk absorption of glucose by facilitated diffusion . Oral preparation of glucose reaches the peak concentration within 40 minutes and the intravenous infusions display 100% bioavailability.

Volume of Distribution

The mean volume of distribution after intravenous infusion is 10.6L.

Route of Elimination

Glucose can be renally excreted.

Half Life

The approximate half-life is 14.3 minutes following intravenous infusion. Gut glucose half-life was markedly higher in females (79 ± 2 min) than in males (65 ± 3 min, P < 0.0001) and negatively related to body height (r = -0.481; P < 0.0001).

Clearance

The mean metabolic clearance rate of glucose (MCR) for the 10 subjects studied at the higher insulin level was 2.27 ± 0.37 ml/kg/min at euglycemia and fell to 1.51±0.21 ml/kg/ at hyperglycemia. The mean MCR for the six subjects studied at the lower insulin level was 1.91 ± 0.31 ml/kg/min at euglyglycemia.

Toxicity

Oral LD50 value in rats is 25800mg/kg. The administration of glucose infusions can cause fluid and/or solute overloading resulting in dilution of the serum electrolyte concentrations, over-hydration, congested states, or pulmonary oedema. Hypersensitivity reactions may also occur including anaphylactic/anaphylactoid reactions from oral tablets and intravenous infusions.

Food Interactions

No interactions found.

Dosage

5% dextrose solution: The dose of Dextropac IV Infusion 5% infusion is variable. It is dependent on individual patient requirements. For 5% dextrose solution, the dose frequently ranges from 500 to 1000 ml. The maximum rate of infusion that will not cause glycosuria is 0.5 g/kg/hour. About 95% is retained when the rate is 0.8 g/kg/hr. the maximum rate of glucose utilization is about 800 mg per kg body weight per hour.

10% dextrose solution: Dose is variable. It depends on the clinical condition, age and body surface area of the patients and the judgment of the physician. Ordinarily, normal circulation is restored by infusing 20-30 ml/kg as rapidly as possible. The laboratory findings should be available by this time so that the physician can proceed more slowly with logically planned subsequent fluid therapy.

25% dextrose solution: The volume and rate of infusion of dextrose solution will depend upon the requirements of the individual patient and the judgment of the physician. The maximum rate at which dextrose can be infused without producing glycosuria is 0.5 g/kg/hr. The usual recommended flow rate for adult is 10-35 drops per minute infused intravenously. It should not be administered by SC or IM route. 25% dextrose solution should be infused through the largest available peripheral vein.

Oral powder:

Adult: 10-20 gm as single dose; may repeat in 10 min if needed.
Child: >2 yr: 10-20 gm as single dose; may repeat in 10 min if needed.

Frequently Asked Questions About Dextropac IV Infusion 5%

1. What is Dextropac IV Infusion 5% used for as a human drug?

Dextropac IV Infusion 5% is a form of glucose, which is a type of sugar. It is used primarily for treating low blood sugar (hypoglycemia), dehydration, and providing a source of energy during parenteral nutrition (IV fluids). It is also used to treat conditions like diabetic ketoacidosis, as it can raise blood sugar levels quickly.

2. How is Dextropac IV Infusion 5% administered to patients?

Dextropac IV Infusion 5% can be administered intravenously (IV) in the form of a solution or as an oral gel in certain cases. The method of administration depends on the patient's condition and the severity of the symptoms.

3. Can Dextropac IV Infusion 5% be given to diabetic patients?

Dextropac IV Infusion 5% is used cautiously in diabetic patients, especially those with type 1 or type 2 diabetes, because it can raise blood glucose levels. It may be given in controlled amounts to treat severe hypoglycemia or to provide an energy source, but blood glucose levels need to be monitored closely.

4. What are the side effects of Dextropac IV Infusion 5%?

Some possible side effects of Dextropac IV Infusion 5% include hyperglycemia (high blood sugar), fluid overload, electrolyte imbalances, and vein irritation if the IV is not properly administered. Long-term use may lead to complications like insulin resistance or weight gain.

5. How does Dextropac IV Infusion 5% work in the body?

Dextropac IV Infusion 5% is rapidly absorbed into the bloodstream, where it increases blood sugar levels. It provides a quick source of energy for cells, especially for those in the brain and muscles. This makes it an essential treatment for hypoglycemia and energy depletion.

6. Can Dextropac IV Infusion 5% be used in emergency situations?

Yes, Dextropac IV Infusion 5% is commonly used in emergency situations to treat hypoglycemia or low blood sugar, especially in unconscious or severely ill patients. It is often administered intravenously in these cases for rapid absorption.

7. What concentration of Dextropac IV Infusion 5% is typically used in IV fluids?

Dextropac IV Infusion 5% is commonly used in concentrations ranging from 5% to 50% in intravenous solutions. The specific concentration depends on the patient's needs and the severity of the condition being treated. A 5% Dextropac IV Infusion 5% solution is often used for hydration, while higher concentrations are used for more urgent treatments like hypoglycemia.

8. Can Dextropac IV Infusion 5% be used to treat dehydration?

Yes, Dextropac IV Infusion 5% is used in combination with saline or other electrolytes in IV solutions to treat dehydration. It helps restore fluids and energy to the body, especially in cases of fluid loss due to illness, vomiting, or diarrhea.

9. Is Dextropac IV Infusion 5% safe for long-term use?

While Dextropac IV Infusion 5% is generally safe when used for short-term treatment of conditions like hypoglycemia, prolonged use or excessive amounts can lead to hyperglycemia, weight gain, and insulin resistance. It is important to use it under medical supervision.

10. Can Dextropac IV Infusion 5% cause weight gain?

Yes, prolonged or excessive use of Dextropac IV Infusion 5% can lead to weight gain, especially if the body consistently absorbs more glucose than it can use. This can increase fat stores and contribute to insulin resistance over time.

11. Is Dextropac IV Infusion 5% safe during pregnancy?

Dextropac IV Infusion 5% is generally considered safe during pregnancy, especially when used to treat hypoglycemia or dehydration. However, like any medication, it should be used under the supervision of a healthcare provider to avoid complications like hyperglycemia or excessive fluid retention.

12. Can Dextropac IV Infusion 5% be used in newborns?

Dextropac IV Infusion 5% is commonly used in newborns, especially in cases of neonatal hypoglycemia or when infants are unable to feed. The solution is usually given intravenously and in carefully controlled amounts to avoid complications such as hyperglycemia.

13. How is Dextropac IV Infusion 5% different from other types of glucose?

Dextropac IV Infusion 5% is a form of glucose that is chemically identical to the sugar found in the human bloodstream. Unlike other forms of glucose, it is more quickly absorbed by the body and provides immediate energy, which is why it is used in emergencies and intravenous solutions.

14. Can Dextropac IV Infusion 5% be used for weight loss?

Dextropac IV Infusion 5% is not recommended for weight loss. It is a sugar that provides energy, which may contribute to weight gain if not used efficiently by the body. For weight loss, a balanced diet and regular exercise are typically recommended.

15. How does Dextropac IV Infusion 5% affect blood sugar levels?

Dextropac IV Infusion 5% rapidly increases blood sugar levels upon entering the bloodstream. It is used to treat hypoglycemia by raising blood sugar levels to normal ranges. However, in individuals with diabetes, it can cause a significant rise in blood glucose levels.

16. What should I do if I experience side effects from Dextropac IV Infusion 5%?

If you experience any side effects from Dextropac IV Infusion 5%, such as signs of hyperglycemia (excessive thirst, frequent urination, fatigue), contact your healthcare provider immediately. They may need to adjust your treatment plan or monitor your blood sugar levels more closely.

17. Can Dextropac IV Infusion 5% be used for energy during exercise?

Dextropac IV Infusion 5% can be used as a quick source of energy during exercise. It is absorbed rapidly by the body and can replenish energy stores in muscles during intense physical activity. However, it should be used in moderation to avoid blood sugar spikes.

18. Is Dextropac IV Infusion 5% the same as sugar?

Yes, Dextropac IV Infusion 5% is a form of glucose, which is the same type of sugar that the body uses for energy. It is often referred to as “blood sugar” because it is the primary sugar found in the bloodstream.

19. Can Dextropac IV Infusion 5% be used for burns?

Dextropac IV Infusion 5% is not used topically for burns, but it may be part of a patient's IV fluid regimen if they are dehydrated due to burn injuries. The goal is to restore fluids and energy to the body.

20. Can Dextropac IV Infusion 5% cause high blood pressure?

In some cases, excessive use of Dextropac IV Infusion 5%, especially when administered in large amounts intravenously, may lead to fluid retention and contribute to elevated blood pressure. It is important to monitor fluid balance during treatment.

21. Can Dextropac IV Infusion 5% be used for cancer patients?

Yes, Dextropac IV Infusion 5% can be used in cancer patients, particularly for those undergoing chemotherapy who may experience nausea, dehydration, or low blood sugar. It can help restore energy and maintain hydration levels.

22. Can Dextropac IV Infusion 5% be used for hypoglycemia in diabetic patients?

Yes, Dextropac IV Infusion 5% is commonly used for treating hypoglycemia (low blood sugar) in diabetic patients, particularly in emergency situations when a quick raise in blood glucose is necessary. It can be given orally or intravenously depending on the severity of the hypoglycemia.

23. How fast does Dextropac IV Infusion 5% work to raise blood sugar?

Dextropac IV Infusion 5% works quickly, typically raising blood sugar levels within 10-15 minutes of administration. It is absorbed rapidly into the bloodstream and provides immediate energy to the body.

24. Can Dextropac IV Infusion 5% cause allergic reactions?

Allergic reactions to Dextropac IV Infusion 5% are rare, but they can occur. Signs of an allergic reaction include rash, itching, difficulty breathing, and swelling. If any of these symptoms occur, seek medical attention immediately.

25. Can Dextropac IV Infusion 5% be used for dehydration in athletes?

Dextropac IV Infusion 5% can be used for hydration in athletes who experience dehydration after intense exercise, particularly when combined with electrolytes to restore balance. However, it should be used in moderation to prevent blood sugar imbalances.

26. How does Dextropac IV Infusion 5% help with brain function?

Since the brain primarily uses glucose for energy, Dextropac IV Infusion 5% helps provide a quick source of fuel for brain cells, especially during periods of low blood sugar. It is often used in emergency situations to treat hypoglycemia and prevent brain dysfunction.

27. Can Dextropac IV Infusion 5% be used for treating ketoacidosis?

Yes, Dextropac IV Infusion 5% is used in the treatment of diabetic ketoacidosis, but it is typically combined with insulin and fluids to help restore normal blood sugar levels and electrolyte balance.

28. How is Dextropac IV Infusion 5% different from sucrose?

Dextropac IV Infusion 5% is a simple sugar (monosaccharide) that is chemically identical to glucose. Sucrose, on the other hand, is a disaccharide made up of glucose and fructose. Dextropac IV Infusion 5% is absorbed more rapidly by the body and is a more direct source of energy.

29. Is Dextropac IV Infusion 5% safe for people with kidney disease?

Dextropac IV Infusion 5% should be used with caution in individuals with kidney disease, especially if they have fluid retention problems. It may require dose adjustments and careful monitoring of electrolytes and fluid balance.

30. Can Dextropac IV Infusion 5% help with nausea?

Dextropac IV Infusion 5% can help improve symptoms of nausea if it is caused by hypoglycemia or low blood sugar. Raising blood glucose levels can alleviate symptoms of nausea and dizziness associated with low sugar.

31. Can Dextropac IV Infusion 5% be used to treat hangovers?

Dextropac IV Infusion 5% can help alleviate some symptoms of a hangover, especially if low blood sugar is contributing to symptoms like dizziness and fatigue. However, it is not a cure for a hangover.

32. Can Dextropac IV Infusion 5% be used as a substitute for regular food?

Dextropac IV Infusion 5% is not a substitute for regular food because it does not provide all the essential nutrients the body needs. It is primarily used as a source of quick energy, especially in medical situations.

33. Can Dextropac IV Infusion 5% cause headaches?

In some cases, Dextropac IV Infusion 5% can cause headaches, particularly if blood sugar levels rise too quickly or if there is an electrolyte imbalance. Monitoring blood glucose levels can help minimize this risk.

34. Can Dextropac IV Infusion 5% be used for hypovolemic shock?

Dextropac IV Infusion 5% can be used as part of IV fluid therapy for hypovolemic shock, but it is usually combined with saline or other electrolytes. The goal is to restore fluid volume and stabilize blood sugar levels.

35. Is Dextropac IV Infusion 5% safe for infants?

Dextropac IV Infusion 5% is commonly used in infants, especially those with low blood sugar or dehydration. It is typically administered intravenously in carefully controlled doses.

36. What is the shelf life of Dextropac IV Infusion 5% solutions?

The shelf life of Dextropac IV Infusion 5% solutions typically ranges from 12 to 24 months, depending on the concentration and storage conditions. Always check the expiration date before use.

37. Can Dextropac IV Infusion 5% help with energy recovery after exercise?

Yes, Dextropac IV Infusion 5% is often used post-exercise to help replenish glycogen stores in muscles and improve energy recovery. It is particularly useful after intense physical activity that depletes the body’s glucose reserves.

38. Can Dextropac IV Infusion 5% be used in combination with other medications?

Dextropac IV Infusion 5% can be safely used with most medications, but it should be monitored in patients taking insulin or other glucose-lowering drugs. It may interact with these medications, requiring adjustments to dosages.

39. Can Dextropac IV Infusion 5% be used to treat seizures?

Dextropac IV Infusion 5% is often used in emergency settings to treat seizures caused by low blood sugar (hypoglycemia). It helps raise blood glucose levels, preventing further seizures caused by glucose depletion.

40. Can Dextropac IV Infusion 5% be taken orally in emergency situations?

Yes, Dextropac IV Infusion 5% can be taken orally in emergency situations, especially in the form of oral glucose gels or tablets. However, if the patient is unconscious or unable to swallow, intravenous administration is preferred.

41. Can Dextropac IV Infusion 5% help with fatigue?

Yes, Dextropac IV Infusion 5% can provide a quick energy boost, which may help alleviate fatigue caused by low blood sugar. It is especially useful in patients with hypoglycemia or those needing rapid energy recovery.

42. Can Dextropac IV Infusion 5% cause kidney damage?

There is no direct evidence that Dextropac IV Infusion 5% causes kidney damage. However, excessive use of Dextropac IV Infusion 5%, especially in patients with pre-existing kidney disease, may contribute to fluid retention and imbalances that could affect kidney function.

43. Can Dextropac IV Infusion 5% be used to treat alcohol poisoning?

Dextropac IV Infusion 5% is sometimes used in the treatment of alcohol poisoning, particularly if low blood sugar is contributing to the symptoms. It helps raise blood glucose levels and stabilize the patient.

44. How does Dextropac IV Infusion 5% compare to other glucose solutions?

Dextropac IV Infusion 5% is a simpler and more rapidly absorbed form of glucose than other types of glucose solutions. It provides a quick energy boost and is often used in emergencies for its fast action.

45. Can Dextropac IV Infusion 5% be used for people with heart disease?

While Dextropac IV Infusion 5% can be used in people with heart disease, it should be done with caution. It may contribute to fluid retention, which could exacerbate heart failure or other cardiac conditions. Monitoring is required during treatment.

46. Can Dextropac IV Infusion 5% cause a spike in insulin levels?

Yes, Dextropac IV Infusion 5% can cause a rapid spike in insulin levels because it raises blood sugar quickly. This may be problematic for individuals with insulin resistance or diabetes.

47. Can Dextropac IV Infusion 5% be used in surgery?

Dextropac IV Infusion 5% is sometimes used in surgical settings to provide energy and maintain blood sugar levels in patients undergoing surgery. It is often combined with other fluids, depending on the patient's needs.

48. Can Dextropac IV Infusion 5% help with hypothermia?

Dextropac IV Infusion 5% can help with hypothermia if the hypothermia is caused by low blood sugar. Raising blood glucose levels can improve energy and promote thermogenesis (heat production), aiding in recovery.

49. What happens if Dextropac IV Infusion 5% is accidentally given too quickly?

If Dextropac IV Infusion 5% is administered too quickly, it can cause a rapid spike in blood sugar, leading to hyperglycemia, fluid overload, and complications like vein irritation. It is important to administer it slowly and monitor the patient’s response.

50. Can Dextropac IV Infusion 5% cause an imbalance in electrolytes?

Yes, excessive use of Dextropac IV Infusion 5%, especially when administered rapidly, can contribute to imbalances in electrolytes like sodium, potassium, and calcium. Close monitoring of electrolyte levels is necessary during treatment.

Medical review

Last reviewed: 24 Jul 2026

Medically reviewed by:

This is general information, not personal medical advice. Consult a doctor before taking any medicine.

Dextropac IV Infusion