Cefadin IM/IV Injection 500 mg/vial Introduction

Cefadin IM/IV Injection 500 mg/vial, also known as cefradine, is a type of antibiotic drug that is used to treat bacterial infections. It belongs to a family of drugs known as cephalosporins, which are similar to penicillin in action. Cefadin IM/IV Injection 500 mg/vial works by killing bacteria that causes infections.

Uses For

Cefadin IM/IV Injection 500 mg/vial is most commonly used to treat infections of the respiratory tract, such as bronchitis and pneumonia, as well as skin and urinary tract infections. It can also be used to treat certain sexually transmitted diseases including gonorrhea and chlamydia.

Mechanism Of Action

Cefadin IM/IV Injection 500 mg/vial works by interfering with the structure of the bacterial cell wall. It inhibits the ability of the bacteria to form and maintain their cell wall, making them susceptible to destruction.

How Long Does It Take To Work?

Cefadin IM/IV Injection 500 mg/vial usually begins to work within a few hours of taking the medication. However, some people may experience relief from symptoms in as little as 24 hours. It usually takes a few days before the infection is completely cleared.

Absorption

Cefadin IM/IV Injection 500 mg/vial is absorbed into the body before it can be effective against the bacteria causing infection. It is best absorbed when taken on an empty stomach, but it can be taken with food if necessary.

Route Of Elimination

Cefadin IM/IV Injection 500 mg/vial is eliminated from the body by the kidneys. It is highly soluble in water, so it is quickly excreted in the urine.

Dosage

For oral administration-
Adults:
  • Urinary tract infections: 500mg four times daily or 1g twice daily. Infections which are severe or chronic may necessitate the administration of higher doses. Where complications arise including prostatitis and epididymitis continued intensive treatment is required.
  • Respiratory tract infections: 250 to 500mg four times daily or 500mg to 1g twice daily, dependent on the site and severity of the infection.
  • Skin and soft tissue infections: 250 to 500mg four times daily or 500mg to 1g twice daily, again dependent on the site and severity of the infection.
Children:
  • Total daily dose of 25 to 50mg/kg given in two or four equally divided doses.
  • Otitis media: Total daily dose of 75 to 100mg/kg given in divided doses 6 to 12 hourly.
  • Maximum daily dosage: 4 gm
Elderly: The normal adult dose is appropriate. Patients with impaired renal or hepatic function should be monitored during treatment.

For injectable administration-
  • Adult: The usual dose is 2-4 gm daily in four equally divided doses up to 8 gm daily. For prophylaxis a single preoperative dose of 1-2 gm intramuscularly or intravenously is given.
  • Children: The dose is 50-100 mg/kg daily in four equally divided doses, up to 300 mg/kg daily in severe infection.

The recommended dosage of cephradine is 250-500mg taken every six to eight hours. For severe infections, the dosage may be increased up to 1g every six to eight hours for adults and 25-50mg/kg every 8 hours for children.

Administration

Cefadin IM/IV Injection 500 mg/vial can be administered orally or intravenously. Oral administration is preferred as it is easier to dose and monitor, and it is less expensive.

Side Effect

The most common side effects of cephradine are gastrointestinal disturbances including nausea, vomiting, diarrhea, and abdominal pain. Other side effects include headache, dizziness, fever, rash, and hypersensitivity reactions.

Toxicity

Cefadin IM/IV Injection 500 mg/vial is generally safe and well tolerated. If taken improperly, there is a risk of severe allergic reactions and kidney damage.

Precaution

Cefadin IM/IV Injection 500 mg/vial should not be taken by people who are allergic to cephalosporins or have kidney or liver disease. It should also not be taken while pregnant or breastfeeding as it can cause harm to the baby.

Interaction

Cefadin IM/IV Injection 500 mg/vial can interact with other medications, including antibiotics, antacids, diuretics, and anticonvulsants. It is important to tell your doctor about all medications you are taking before starting cephradine to avoid any potential interactions.

Disease Interaction

Cefadin IM/IV Injection 500 mg/vial can interact with certain diseases, such as kidney or liver disease, as well as certain conditions, such as colitis. It is important to inform your doctor about any disease or condition you have before taking cephradine.

Drug Interaction

Cefadin IM/IV Injection 500 mg/vial can interact with certain drugs, including anticoagulants, warfarin, phenytoin, and aspirin. It is important to tell your doctor about all medications you are taking before starting cephradine to avoid any potential interactions.

Food Interactions

Cefadin IM/IV Injection 500 mg/vial can interact with certain foods including dairy products, iron supplements, and antacids. It is important to inform your doctor about any foods you are consuming before taking cephradine.

Pregnancy Use

Cefadin IM/IV Injection 500 mg/vial should be avoided by pregnant women as it can harm the developing baby. If the benefits of treatment outweighs the risks, your doctor may decide to prescribe cephradine.

Lactation Use

Cefadin IM/IV Injection 500 mg/vial should be avoided by nursing mothers as it can be secreted into breast milk. If necessary, your doctor may decide to prescribe cephradine while breastfeeding.

Acute Overdose

In the event of an acute overdose of cephradine, seek emergency medical help. Symptoms of an acute overdose of cephradine may include stomach cramps, nausea, vomiting, and confusion.

Contraindication

Cefadin IM/IV Injection 500 mg/vial should not be taken by people who are allergic to cephalosporins or have kidney or liver disease. It should also not be taken while pregnant or breastfeeding as it can cause harm to the baby.

Use Direction

Cefadin IM/IV Injection 500 mg/vial should be taken as directed by a doctor. Do not exceed the recommended dosage, as this may cause side effects. Take the medication as prescribed and do not stop taking it without doctor's advice.

Storage Condition

Cefadin IM/IV Injection 500 mg/vial should be stored at room temperature, away from moisture and heat. Do not allow the medication to freeze. Keep the medication out of the reach of children and pets.

Volume Of Distribution

The volume of distribution of cephradine is about 0.45 L/kg. This means that it is distributed relatively quickly within the body after administration.

Half Life

The half-life of cephradine is about 0.9-1.2 hours. This means that it is quickly eliminated from the body and has a short duration of action.

Clearance

The clearance of cephradine is about 0.47-0.56 L/h/kg. This means that it is eliminated quickly from the body and the risk of side effects is low.

See in details version Cefadin IM/IV Injection 500 mg/vial also Cefadin IM/IV Injection 500 mg/vial in bangla

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Uses

Some Frequently Asked Questions About Cefadin IM/IV Injection 500 mg/vial

1. What is Cefadin IM/IV Injection 500 mg/vial?

Cefadin IM/IV Injection 500 mg/vial is a first-generation cephalosporin antibiotic used to treat bacterial infections in humans.

2. What types of infections does Cefadin IM/IV Injection 500 mg/vial treat?

Cefadin IM/IV Injection 500 mg/vial is used to treat respiratory tract infections, skin infections, urinary tract infections (UTIs), and certain ear infections.

3. How does Cefadin IM/IV Injection 500 mg/vial work?

Cefadin IM/IV Injection 500 mg/vial works by inhibiting bacterial cell wall synthesis, leading to bacterial death.

4. Is Cefadin IM/IV Injection 500 mg/vial available over the counter?

No, Cefadin IM/IV Injection 500 mg/vial is a prescription antibiotic and must be prescribed by a doctor.

5. How should I take Cefadin IM/IV Injection 500 mg/vial?

Cefadin IM/IV Injection 500 mg/vial should be taken exactly as prescribed by your doctor, usually with or without food.

6. What is the typical dosage of Cefadin IM/IV Injection 500 mg/vial?

  • Adults: 250-500 mg every 6 hours, depending on the infection.
  • Children: Dosage is based on body weight and infection severity.

7. Can Cefadin IM/IV Injection 500 mg/vial be taken on an empty stomach?

Yes, but taking it with food may help reduce stomach upset.

8. What are the common side effects of Cefadin IM/IV Injection 500 mg/vial?

Common side effects include nausea, diarrhea, stomach pain, and mild skin rash.

9. Can pregnant women take Cefadin IM/IV Injection 500 mg/vial?

Cefadin IM/IV Injection 500 mg/vial is generally considered safe during pregnancy but should be used under medical supervision.

10. Can breastfeeding mothers take Cefadin IM/IV Injection 500 mg/vial?

Yes, but small amounts may pass into breast milk. Consult your doctor before use.

11. How long does it take for Cefadin IM/IV Injection 500 mg/vial to work?

Symptoms often improve within 48 hours, but the full course should be completed to prevent antibiotic resistance.

12. What should I do if I miss a dose?

Take the missed dose as soon as you remember, but skip it if it's almost time for your next dose. Do not double dose.

13. Can Cefadin IM/IV Injection 500 mg/vial be used for children?

Yes, but the dosage depends on the child’s weight and the severity of the infection.

14. What should I avoid while taking Cefadin IM/IV Injection 500 mg/vial?

Avoid alcohol and do not skip doses, as this can reduce the effectiveness of the antibiotic.

15. Can Cefadin IM/IV Injection 500 mg/vial treat viral infections like colds or flu?

No, Cefadin IM/IV Injection 500 mg/vial is only effective against bacterial infections.

16. Is Cefadin IM/IV Injection 500 mg/vial safe for people with kidney disease?

People with kidney disease may require a lower dose. Consult your doctor.

17. Can I drink alcohol while taking Cefadin IM/IV Injection 500 mg/vial?

It is best to avoid alcohol, as it may increase the risk of side effects like nausea and dizziness.

18. What happens if I take too much Cefadin IM/IV Injection 500 mg/vial?

Overdose symptoms may include nausea, vomiting, stomach pain, or seizures. Seek medical attention immediately.

19. Does Cefadin IM/IV Injection 500 mg/vial interact with other medications?

Yes, Cefadin IM/IV Injection 500 mg/vial may interact with blood thinners, diuretics, and other antibiotics. Inform your doctor about all medicines you are taking.

20. Can Cefadin IM/IV Injection 500 mg/vial be used for tooth infections?

Yes, Cefadin IM/IV Injection 500 mg/vial may be prescribed for bacterial tooth infections.

21. Can I take Cefadin IM/IV Injection 500 mg/vial for urinary tract infections (UTIs)?

Yes, Cefadin IM/IV Injection 500 mg/vial is commonly prescribed for UTIs.

22. Can Cefadin IM/IV Injection 500 mg/vial treat pneumonia?

Yes, Cefadin IM/IV Injection 500 mg/vial can be used to treat mild to moderate pneumonia.

23. Does Cefadin IM/IV Injection 500 mg/vial kill all bacteria?

No, it is effective against certain gram-positive and gram-negative bacteria.

24. Can Cefadin IM/IV Injection 500 mg/vial be used for ear infections?

Yes, it is sometimes prescribed for bacterial ear infections.

25. Does Cefadin IM/IV Injection 500 mg/vial cause diarrhea?

Yes, diarrhea is a possible side effect.

26. Is Cefadin IM/IV Injection 500 mg/vial a penicillin?

No, but it belongs to a related class of antibiotics called cephalosporins.

27. Can I take Cefadin IM/IV Injection 500 mg/vial with paracetamol?

Yes, Cefadin IM/IV Injection 500 mg/vial can be taken with paracetamol if needed for pain or fever.

28. Can Cefadin IM/IV Injection 500 mg/vial cause allergic reactions?

Yes, signs of an allergic reaction include rash, swelling, and difficulty breathing. Seek medical help if this occurs.

29. Does Cefadin IM/IV Injection 500 mg/vial make you sleepy?

Drowsiness is not a common side effect, but some people may feel fatigued.

30. Can I stop taking Cefadin IM/IV Injection 500 mg/vial if I feel better?

No, always complete the full course to prevent antibiotic resistance.

31. Can Cefadin IM/IV Injection 500 mg/vial treat skin infections?

Yes, it is used for bacterial skin infections.

32. Can Cefadin IM/IV Injection 500 mg/vial cause stomach pain?

Yes, mild stomach discomfort is a common side effect.

33. How should Cefadin IM/IV Injection 500 mg/vial be stored?

Store at room temperature, away from moisture and heat.

34. Does Cefadin IM/IV Injection 500 mg/vial cause yeast infections?

Yes, prolonged use may lead to yeast infections.

35. Can Cefadin IM/IV Injection 500 mg/vial cause headaches?

Headaches are a possible but uncommon side effect.

36. Can Cefadin IM/IV Injection 500 mg/vial be given intravenously?

No, Cefadin IM/IV Injection 500 mg/vial is usually taken orally or via injection.

37. Can Cefadin IM/IV Injection 500 mg/vial be used for food poisoning?

Only if caused by susceptible bacteria, not for viral food poisoning.

38. Can Cefadin IM/IV Injection 500 mg/vial be taken long-term?

No, it is meant for short-term use only.

39. Does Cefadin IM/IV Injection 500 mg/vial affect birth control pills?

It may reduce their effectiveness. Use additional contraception.

40. Can Cefadin IM/IV Injection 500 mg/vial cause dizziness?

Dizziness is an uncommon but possible side effect.

41. Is Cefadin IM/IV Injection 500 mg/vial safe for elderly patients?

Yes, but kidney function should be monitored.

42. Can Cefadin IM/IV Injection 500 mg/vial treat bronchitis?

Yes, it is sometimes prescribed for bacterial bronchitis.

43. Can Cefadin IM/IV Injection 500 mg/vial cause liver damage?

Rarely, but liver function should be monitored in long-term use.

44. Can Cefadin IM/IV Injection 500 mg/vial be used for gonorrhea?

No, other antibiotics like ceftriaxone are preferred.

45. Does Cefadin IM/IV Injection 500 mg/vial cause sun sensitivity?

Sun sensitivity is not a common side effect.

46. Can Cefadin IM/IV Injection 500 mg/vial treat typhoid fever?

No, other antibiotics like ciprofloxacin are preferred.

47. Can Cefadin IM/IV Injection 500 mg/vial cause weight loss?

Weight loss is not a common side effect.

48. Can I take Cefadin IM/IV Injection 500 mg/vial if I have diabetes?

Yes, but monitor blood sugar levels as some antibiotics may affect them.

49. Can Cefadin IM/IV Injection 500 mg/vial be used for sinus infections?

Yes, it is sometimes prescribed for bacterial sinus infections.

50. How long should I take Cefadin IM/IV Injection 500 mg/vial?

Take it for the full duration prescribed by your doctor.

*** Taking medicines without doctor's advice can cause long-term problems.
Dr. Uttom Kumar Shet

Dr. Uttom Kumar Shet

Dental Implant Specialist and Course Director (Osstem Implant), Maxillofacial Surgery

Dentist in Dhaka
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