Brand Name Alice
Type Lotion
Weight 0.5%
Generic Ivermectin
Manufacturer Square Pharmaceuticals Ltd.
Price 60 gm tube: ৳ 130.00

About Alice

Alice Lotion (Square Pharmaceuticals Ltd.) is a brand medicine containing the generic Ivermectin . Current listed price in Bangladesh: 60 gm tube: ৳ 130.00.

Medical information for Alice Lotion 0.5%

Uses, dosage, side effects, and safety details below apply to Alice Lotion 0.5% (generic: Ivermectin). This is general information — consult a doctor before use.

Introduction

Alice Lotion 0.5% is a broad-spectrum anti-parasite medication. It was approved for the topical treatment of head lice infestations in patients 6 months of age and older. Alice Lotion 0.5% is mainly used in humans in the treatment of onchocerciasis, but is also effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis and enterobiasis).

Uses

Alice Lotion 0.5% is an anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.

For the treatment of intestinal (i.e., nondisseminated) strongyloidiasis due to the nematode parasite Strongyloides stercoralis. Also for the treatment of onchocerciasis (river blindness) due to the nematode parasite Onchocerca volvulus. Can be used to treat scabies caused by Sarcoptes scabiei.

Associated Conditions

  • Acne Rosacea
  • Ascaris lumbricoides infection
  • Cutaneous larva migrans
  • Demodicidosis
  • Gnathostomiasis
  • Mansonella ozzardi infection
  • Mansonella streptocerca infection
  • Oesophagostomiasis
  • Onchocerciasis
  • Pediculosis Capitis
  • Scabies
  • Trichuriasis
  • Wuchereria bancroftii infection

Pharmacodynamics

Alice Lotion 0.5% is a semisynthetic, anthelminitic agent. It is an avermectin which a group of pentacyclic sixteen-membered lactone (i.e. a macrocyclic lactone disaccharide) derived from the soil bacterium Streptomyces avermitilis. Avermectins are potent anti-parasitic agents. Alice Lotion 0.5% is the most common avermectin. It is a broad spectrum antiparasitic drug for oral administration. It is sometimes used to treat human onchocerciasis (river blindness). It is the mixture of 22,23-dihydro-avermectin B1a (at least 90%) and 22,23-dihydro-avermectin B1b (less than 10%).

Mechanism of Action

Alice Lotion 0.5% binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding causes an increase in the permeability of the cell membrane to chloride ions and results in hyperpolarization of the cell, leading to paralysis and death of the parasite. Alice Lotion 0.5% also is believed to act as an agonist of the neurotransmitter gamma-aminobutyric acid (GABA), thereby disrupting GABA-mediated central nervous system (CNS) neurosynaptic transmission. Alice Lotion 0.5% may also impair normal intrauterine development of O. volvulus microfilariae and may inhibit their release from the uteri of gravid female worms.

Absorption

Moderately well absorbed. Improved absorption with high fat meal.

Volume of Distribution

The volume of distribution is 3 to 3.5 L/kg and it does not cross the blood-brain barrier.

Protein Binding

93%

Route of Elimination

Alice Lotion 0.5% is metabolized in the liver, and ivermectin and/or its metabolites are excreted almost exclusively in the feces over an estimated 12 days, with less than 1% of the administered dose excreted in the urine.

Half Life

16 hours (also reported at 22-28 hours)

Toxicity

LD50 = 29.5 mg/kg (Mouse, oral). LD50 = 10 mg/kg (Rat, oral). Adverse effects include muscle or joint pain, dizziness, fever, headache, skin rash, fast heartbeat.

Food Interactions

  • Take on an empty stomach.

Frequently Asked Questions About Alice Lotion 0.5%

1. What is Alice Lotion 0.5%?

Alice Lotion 0.5% is an antiparasitic medication used to treat a variety of parasitic infections, including those caused by roundworms, scabies, and lice.

2. How does Alice Lotion 0.5% work?

Alice Lotion 0.5% works by binding to specific channels in the nervous system of parasites, causing paralysis and death of the parasites.

3. What conditions is Alice Lotion 0.5% used to treat?

Alice Lotion 0.5% is used to treat conditions such as:

  • Onchocerciasis (river blindness)
  • Lymphatic filariasis
  • Strongyloidiasis
  • Scabies
  • Head lice
  • Trichuriasis

4. How is Alice Lotion 0.5% taken?

Alice Lotion 0.5% is typically taken orally as a tablet, although the dosage and frequency depend on the type of infection being treated. Follow your doctor's instructions regarding dosage.

5. What is the usual dosage of Alice Lotion 0.5%?

The dosage of Alice Lotion 0.5% depends on the condition being treated and the patient's weight. It is usually taken as a single dose, but multiple doses may be needed depending on the infection.

6. Can I take Alice Lotion 0.5% with food?

Alice Lotion 0.5% can be taken with or without food. However, it is often recommended to take it with food to improve absorption.

7. Can I take Alice Lotion 0.5% if I am pregnant?

Alice Lotion 0.5% is generally not recommended during pregnancy, especially in the first trimester. Consult your doctor before using Alice Lotion 0.5% if you are pregnant.

8. Is Alice Lotion 0.5% safe to use while breastfeeding?

Alice Lotion 0.5% may pass into breast milk in small amounts. It is recommended to consult your doctor before using Alice Lotion 0.5% while breastfeeding.

9. What are the side effects of Alice Lotion 0.5%?

Common side effects of Alice Lotion 0.5% may include:

  • Dizziness
  • Fatigue
  • Headache
  • Nausea
  • Diarrhea

10. Can Alice Lotion 0.5% cause serious side effects?

Serious side effects are rare but may include:

  • Severe allergic reactions (rash, itching, swelling, difficulty breathing)
  • Vision problems
  • Severe dizziness or fainting
  • Severe abdominal pain
If any of these occur, seek immediate medical attention.

11. Can Alice Lotion 0.5% interact with other medications?

Alice Lotion 0.5% may interact with other medications. Inform your doctor of all the medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements.

12. Can I take Alice Lotion 0.5% with alcohol?

There is no known direct interaction between Alice Lotion 0.5% and alcohol. However, alcohol may exacerbate side effects like dizziness and drowsiness. It's advisable to limit alcohol intake.

13. Can Alice Lotion 0.5% be used for pets?

Alice Lotion 0.5% is used in veterinary medicine to treat parasitic infections in animals. However, the dosages for humans and animals differ significantly, and you should never use veterinary Alice Lotion 0.5% on yourself.

14. Is Alice Lotion 0.5% available over-the-counter?

Alice Lotion 0.5% is available only by prescription for human use. It is not typically available over-the-counter.

15. What should I do if I miss a dose of Alice Lotion 0.5%?

If you miss a dose, take it as soon as you remember, unless it is almost time for the next dose. Do not double the dose to make up for a missed one.

16. What should I do if I overdose on Alice Lotion 0.5%?

In case of overdose, seek immediate medical help. Symptoms of overdose may include severe dizziness, confusion, or loss of consciousness.

17. How long does Alice Lotion 0.5% take to work?

The effectiveness of Alice Lotion 0.5% depends on the condition being treated. For some conditions, such as scabies or head lice, improvement is usually seen within a few days. For other infections, it may take longer.

18. Can Alice Lotion 0.5% be used to treat COVID-19?

Although Alice Lotion 0.5% has been studied for use against COVID-19, it has not been approved by the FDA for this purpose. Always follow your healthcare provider's advice regarding COVID-19 treatment.

19. Can Alice Lotion 0.5% help with skin conditions?

Alice Lotion 0.5% is used to treat skin conditions like scabies and rosacea. It works by reducing inflammation and killing the parasites responsible for these conditions.

20. Is Alice Lotion 0.5% effective for head lice?

Yes, Alice Lotion 0.5% is effective for treating head lice by killing both the adult lice and their eggs. It is usually prescribed as a topical treatment or oral medication.

21. Can I take Alice Lotion 0.5% for ringworm?

Alice Lotion 0.5% is not typically used to treat fungal infections like ringworm. Other antifungal treatments are generally more effective for these conditions.

22. Can Alice Lotion 0.5% treat intestinal worms?

Alice Lotion 0.5% is effective against a variety of intestinal worms, including strongyloides and some other parasitic roundworms.

23. How is Alice Lotion 0.5% used to treat river blindness?

Alice Lotion 0.5% is used to treat onchocerciasis (river blindness) by killing the larvae of the Onchocerca volvulus parasite, which is transmitted by blackflies.

24. Can Alice Lotion 0.5% cause dizziness?

Dizziness is a possible side effect of Alice Lotion 0.5%. If you experience dizziness, avoid driving or operating heavy machinery until the symptoms resolve.

25. How is Alice Lotion 0.5% used for scabies?

Alice Lotion 0.5% is used for treating scabies by killing the mites that cause the skin condition. It may be prescribed as an oral medication or topical treatment in severe cases.

26. How does Alice Lotion 0.5% affect the immune system?

Alice Lotion 0.5% does not typically affect the immune system directly. However, by eliminating parasites, it helps reduce inflammation and the immune response triggered by the infection.

27. Can Alice Lotion 0.5% be used for acne?

Alice Lotion 0.5% is sometimes used for treating rosacea, a skin condition that can cause acne-like symptoms. It is not typically used for regular acne.

28. Can I take Alice Lotion 0.5% for allergies?

Alice Lotion 0.5% is not used to treat allergies. It is an antiparasitic medication and does not affect allergic reactions or symptoms.

29. Can I take Alice Lotion 0.5% if I have liver disease?

Alice Lotion 0.5% should be used with caution in people with liver disease. Your doctor may adjust the dose or monitor liver function closely during treatment.

30. Does Alice Lotion 0.5% affect blood pressure?

Alice Lotion 0.5% does not typically affect blood pressure. However, if you experience dizziness or fainting, inform your healthcare provider.

31. Can Alice Lotion 0.5% be used for malaria?

Alice Lotion 0.5% is not used to treat malaria. Antimalarial medications are typically prescribed for the treatment of malaria.

32. Can I take Alice Lotion 0.5% for pinworms?

Alice Lotion 0.5% is effective in treating pinworm infections, which are caused by the Enterobius vermicularis parasite. It works by killing the pinworms in the intestines.

33. Can Alice Lotion 0.5% treat tapeworms?

Alice Lotion 0.5% is effective for treating some types of tapeworm infections, but it is not the drug of choice for all types. Other medications, such as praziquantel, may be preferred for tapeworms.

34. Does Alice Lotion 0.5% cause hair loss?

Hair loss is not a common side effect of Alice Lotion 0.5%. However, if you experience hair loss or scalp irritation, consult your healthcare provider.

35. How is Alice Lotion 0.5% used to treat lymphatic filariasis?

Alice Lotion 0.5% is used to treat lymphatic filariasis by killing the microfilariae (larval stage) of the Wuchereria bancrofti parasite, which causes the condition.

36. Can Alice Lotion 0.5% be used for COVID-19 prevention?

There is no evidence that Alice Lotion 0.5% is effective in preventing COVID-19. It is important to follow the guidelines provided by health authorities regarding COVID-19 prevention.

37. Can Alice Lotion 0.5% help with chronic itching?

Alice Lotion 0.5% can help relieve itching caused by scabies and other parasitic skin infestations. It is not typically used for chronic itching unrelated to parasitic infections.

38. What should I do if I have an allergic reaction to Alice Lotion 0.5%?

If you have an allergic reaction (rash, swelling, difficulty breathing), stop taking Alice Lotion 0.5% immediately and seek emergency medical help.

39. Can Alice Lotion 0.5% cause muscle weakness?

Muscle weakness is not a common side effect of Alice Lotion 0.5%. If you experience muscle weakness or other unusual symptoms, consult your doctor.

40. Can I take Alice Lotion 0.5% if I have kidney disease?

Alice Lotion 0.5% should be used cautiously in people with kidney disease. Your doctor may adjust the dose or monitor kidney function during treatment.

41. Is Alice Lotion 0.5% effective against COVID-19 variants?

There is no evidence supporting the effectiveness of Alice Lotion 0.5% against COVID-19 variants. Do not use Alice Lotion 0.5% for COVID-19 unless directed by a healthcare provider.

42. Can I take Alice Lotion 0.5% for a skin infection?

Alice Lotion 0.5% is not used for bacterial skin infections. It is used primarily for parasitic skin conditions like scabies and head lice.

43. Can Alice Lotion 0.5% help with itching caused by dermatitis?

Alice Lotion 0.5% is not typically used for dermatitis. If itching is caused by a parasitic infection like scabies, Alice Lotion 0.5% can help relieve symptoms.

44. Is Alice Lotion 0.5% effective for treating hookworms?

Alice Lotion 0.5% is effective against hookworms, as it works by targeting the parasites in the gastrointestinal tract.

45. Can Alice Lotion 0.5% cause drowsiness?

Drowsiness is not a common side effect of Alice Lotion 0.5%. However, if you feel drowsy or fatigued after taking Alice Lotion 0.5%, avoid operating heavy machinery.

46. Can Alice Lotion 0.5% be used in combination with other medications?

Alice Lotion 0.5% may be used in combination with other medications for certain parasitic infections. Always consult your healthcare provider for advice on drug interactions.

47. How should I store Alice Lotion 0.5%?

Alice Lotion 0.5% should be stored at room temperature in a dry place, away from moisture and heat. Keep the medication in its original packaging.

48. Can Alice Lotion 0.5% cause nausea?

Nausea is a possible side effect of Alice Lotion 0.5%. If nausea persists or becomes severe, contact your healthcare provider.

49. Does Alice Lotion 0.5% work for all types of parasitic infections?

Alice Lotion 0.5% is effective against a variety of parasitic infections, but not all. Some infections may require different treatments.

50. Can I take Alice Lotion 0.5% if I have a weakened immune system?

If you have a weakened immune system, consult your healthcare provider before taking Alice Lotion 0.5%. The dosage may need to be adjusted.

Medical review

Last reviewed: 24 Jul 2026

Medically reviewed by:

This is general information, not personal medical advice. Consult a doctor before taking any medicine.

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