Translation MCQ 1031+

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• What drives the conformational change in the ribosome?
  ক

  GTP hydrolysis

  খ

  AMP hydrolysis

  গ

  ATP hydrolysis

  ঘ

  GDP hydrolysis
• The first amino acid incorporated at the N-terminus of polypeptide is ___________________
  ক

  methionine

  খ

  cysteine

  গ

  tryptophan

  ঘ

  valine
• Initiation factors are ______________________
  ক

  lipids

  খ

  soluble proteins

  গ

  lipopolysaccharides

  ঘ

  phospholipids
• Shine-Dalgarno sequence is present in the ____________________
  ক

  hnRNA

  খ

  mRNA

  গ

  tRNA

  ঘ

  siRNA
• Which of the following is an initiation codon?
  ক

  AAA

  খ

  AUG

  গ

  AGU

  ঘ

  AGG
• Which of the following moves in consecutive blocks of three nucleotides?
  ক

  ribosome

  খ

  ribozyme

  গ

  polymerase

  ঘ

  helicase
• The synthesis of polypeptide can be divided into ______ distinct activities.
  ক

  1

  খ

  2

  গ

  3

  ঘ

  4
• Which of the following antibiotic acts by competitively inhibiting the peptidyl transferase activity of prokaryotic ribosomes?
  ক

  Puromycin

  খ

  Vancomycin

  গ

  Tetracycline

  ঘ

  Chloramphenicol
• The peptidyl transferase center that catalyzes the peptide bond formation is located on the smaller subunit and consists entirely of rRNA.
  ক

  True

  খ

  False
• First, the bond between the amino acid and the tRNA in the P site is cleaved, then the peptide bond is formed between the two amino acids.
  ক

  False

  খ

  True
• Which of the following proteins bind to the ribosome and causes the dissociation of the two ribosomal subunits from mRNA?
  ক

  RF 1

  খ

  RF 2

  গ

  RF 3

  ঘ

  RRF
• With the help of which of the following proteins does the ribosome recognize the stop codon?
  ক

  Cleavage Factors (CF)

  খ

  Elimination Factors (EF)

  গ

  Termination Factors (TF)

  ঘ

  Release Factors (RF)
• Which of the following rRNA is intimately involved with the peptidyl transferase activity?
  ক

  5S rRNA

  খ

  16S rRNA

  গ

  28S rRNA

  ঘ

  23S rRNA
• The second and further aminoacyl-tRNAs are brought to the ribosome bound to which of the following protein complex?
  ক

  EF-Ts-ATP

  খ

  EF-Ts-GTP

  গ

  EF-Tu-ATP

  ঘ

  EF-Tu-GTP
• Which of the following initiation factor bring the initiator tRNA?
  ক

  IF-4

  খ

  IF-3

  গ

  IF-1

  ঘ

  IF-2
• Which of the following initiation factor when bound to the 30S subunit blocks the A site, so that only the P site is available for the initiator tRNA to bind to?
  ক

  IF-4

  খ

  IF-2

  গ

  IF-3

  ঘ

  IF-1
• Base pairing between mRNA and which of the following rRNAs help in the selection of translation initiation site?
  ক

  5.8S rRNA

  খ

  5S rRNA

  গ

  28S rRNA

  ঘ

  16S rRNA
• In prokaryotes and eukaryotes, multiple ribosomes can bind to a single mRNA transcript, and give rise to beads on a string structure. What is this structure called?
  ক

  Monosome

  খ

  Multiribosome

  গ

  Oligosome

  ঘ

  Polysome
• The ribosome reads mRNA in which of the following direction?
  ক

  Both 3’ → 5’ and 5’ → 3’

  খ

  Either 3’ → 5’ or 5’ → 3’

  গ

  3’ → 5’ direction only

  ঘ

  5’ → 3’ direction only
• In which of the following directions does the polypeptide synthesis proceeds?
  ক

  From both N-terminus and C-terminus

  খ

  Either from N-terminus or C-terminus

  গ

  C-terminus to N-terminus

  ঘ

  N-terminus to C-terminus
• What is the process of synthesis of a polypeptide chain from mRNA known as?
  ক

  Conversion

  খ

  Replication

  গ

  Transcription

  ঘ

  Translation
• Where are the untranslated regions (UTRs) present?
  ক

  At both the 5’ and the 3’ ends

  খ

  At only the 5’ end

  গ

  At only the 3’ end

  ঘ

  Outer to the 5’ and the 3’ end
• Which of the following is the start codon?
  ক

  UAA

  খ

  UAG

  গ

  AUG

  ঘ

  UGA
• What happens when the small subunit of the ribosome encounters an mRNA?
  ক

  Separation of the small and the larger subunit of the ribosome

  খ

  Translation of the central dogma of DNA

  গ

  Joining of the small and the larger subunit of the ribosome

  ঘ

  Transcription of the central dogma of DNA
• How many types of proteins are present inside a single ribosome?
  ক

  40

  খ

  60

  গ

  80

  ঘ

  100
• Which of the following cell organelle is responsible for the synthesis of proteins?
  ক

  Lysosomes

  খ

  Mitochondria

  গ

  Nucleus

  ঘ

  Ribosomes
• The presence of a catalyst would decrease the rate of formation of a peptide bond.
  ক

  True

  খ

  False
• What is the process of activation of amino acids in the presence of ATP and its linkage to their cognate tRNA known as?
  ক

  Charging of tRNA

  খ

  Charging of ATP

  গ

  Aminoacetylation of tRNA

  ঘ

  Aminoacetylation of ATP
• What is the process of polymerisation of polypeptides to amino acids known as?
  ক

  Transcription

  খ

  Translation

  গ

  Reverse transcription

  ঘ

  Reverse translation
• ’তুমি কি আজ রাতে আসবে? বাক্যটির সঠিক ইংরেজি অনুবাদ হলো-
  ক

  Will you come today night

  খ

  Will you come tonight

  গ

  Will you come this night

  ঘ

  Will you come present night