Cns pharmacology MCQ 91+

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• Drugs responsible for drug-induced lupus
  ক

  Procainamide

  খ

  Hydralazine

  গ

  Quinidine

  ঘ

  Isoniazide

  ঙ

  Phenobarbitone
• Systemic lupus erythematosus can be caused by
  ক

  Hydralazine

  খ

  Procainamide

  গ

  Isoniazide

  ঘ

  Carbamazepine

  ঙ

  Metronidazole
• Chloroquine
  ক

  Can be administered orally

  খ

  May cause irreversible visual loss when used as prolonged therapy

  গ

  Injures plasmodium when the parasite is extracellular

  ঘ

  Should not be co-adminstered with proguanil

  ঙ

  Is contraindicated in children under 10 years
• Hydroxychloroquine is used in the treatment of
  ক

  Rheumatoid arthritis

  খ

  Malaria

  গ

  Systemic lupus erythematosus

  ঘ

  Rheumatic fever

  ঙ

  Filariasis
• Adverse effects of pyrazinamide are
  ক

  Arthralgia

  খ

  Hepatotoxicity

  গ

  Hyperuricemia

  ঘ

  Nephrotoxicity

  ঙ

  Optic neuritis
• The antitubercular drugs those should not be used in pregnancy are
  ক

  Streptomycin

  খ

  Ciprofloxacin

  গ

  INH

  ঘ

  Rifampicin

  ঙ

  Ethambutol
• The Second-line antitubercular drugs are
  ক

  Streptomycin

  খ

  PAS

  গ

  Ethionamide

  ঘ

  Pyrazinamide

  ঙ

  Rifampicin
• Anti-tubercular drugs causing hepatotoxicity are
  ক

  Pyrazinamide

  খ

  Isonicotinic acid hydrazide

  গ

  Rifampicin

  ঘ

  Streptomycin

  ঙ

  Ethambutol
• The following adverse effects are correctly paired with anti TB drugs
  ক

  Peripheral neuropathy→ Isoniazide

  খ

  Hyperuricemia→ Pyrazinamide

  গ

  Retrobulber neuritis→ Ethambutol

  ঘ

  Ototoxicity→ Rifampicin

  ঙ

  Hepatotoxicity→ Streptomycin
• Chemotherapeutic drugs causing severe vomiting include
  ক

  Cisplatin

  খ

  Doxorubicin

  গ

  5-Flurouracil

  ঘ

  Actinomycin-D

  ঙ

  Methotrexate
• The anti-emetic drugs that block D2 receptors in CTZ are
  ক

  Prochlorperazine

  খ

  Metoclopramide

  গ

  Domperidone

  ঘ

  Cyclizine

  ঙ

  Granisetron
• The receptors involved in vomiting are
  ক

  Dopamine

  খ

  Histamine

  গ

  Serotonin

  ঘ

  Nicotine

  ঙ

  α-adrenoceptor
• Cytotoxic drug- induced vomiting can be prevented by
  ক

  Domperidone

  খ

  Ondansetrone

  গ

  Meclizine

  ঘ

  Metoclopramide

  ঙ

  Promethazine
• Anti-emetic drugs are
  ক

  Meclizine

  খ

  Domperidone

  গ

  Ondansetron

  ঘ

  Dopamine

  ঙ

  Metformin
• Peptic ulcer pain is typically relieved by
  ক

  Raising the pH of the fluid bathing the ulcer

  খ

  A drug which blocks the gastric proton pump

  গ

  Oral administration of sodium bicarbonate

  ঘ

  Oral administration of antispasmodics

  ঙ

  A drug which interferes with the action of acetylcholinesterase
• H2-antagonists
  ক

  May cause impotence

  খ

  Decrease both basal and stimulated acid secretion

  গ

  Increase plasma gastrin level

  ঘ

  Are contraindicated in renal failure

  ঙ

  Are cytoprotective
• Triple drug therapy for H. pylori eradication contains
  ক

  Amoxicillin

  খ

  Lansoprazole

  গ

  Clarithromycin

  ঘ

  Flucloxacillin

  ঙ

  Erythromycin
• Cytoprotective drugs used in PUD are
  ক

  Bismuth chelate

  খ

  Misoprostol

  গ

  Sucralfate

  ঘ

  Pantoprazole

  ঙ

  Ranitidine
• Proton-pump inhibitors are
  ক

  Omeprazole

  খ

  Pantoprazole

  গ

  Sucralfate

  ঘ

  Famotidine

  ঙ

  Misoprostol
• Adverse effects of ketamine hydrochloride are
  ক

  Increased salivation

  খ

  Hypertension

  গ

  Hallucination

  ঘ

  Bradycardia

  ঙ

  Bronchoconstriction
• Ketamine
  ক

  Causes profound analgesia

  খ

  Causes hallucination

  গ

  Usually produces bradycardia and fall of BP

  ঘ

  Produces muscle relaxation

  ঙ

  Decreases intracranial and intraocular pressure
• Surgical anaesthesia induced with ether is
  ক

  Accompanied by good muscle relaxation

  খ

  Dangerous because of the risk of explosion

  গ

  Rapid

  ঘ

  Accompanied by increased myocardial contractility

  ঙ

  Associatwith a higher incidence of hepatitis than with other anaesthetics
• Nitrous oxide
  ক

  Has powerful analgesic property

  খ

  After cessation of administration

  গ

  may produce diffusion hypoxia

  ঘ

  Is a powerful muscle relaxant

  ঙ

  Is contraindicated if pethidine has been administered

  চ

  Should not be premixed with oxygen
• The following anaesthetic agents cause direct sympathetic stimulation
  ক

  Ketamine

  খ

  Seroflurane

  গ

  Desflurane

  ঘ

  Halothane

  ঙ

  Isoflurane
• Aspirationmay occur during induction of anaesthesia in
  ক

  Full stomach

  খ

  Obstetrical patient

  গ

  Hiatus hernia

  ঘ

  Fasting more than 6 hours

  ঙ

  Aspiration of gastric content before operation
• Local anaesthetic agents are
  ক

  Bupivacaine

  খ

  Lignocaine

  গ

  Procaine

  ঘ

  Adrenaline

  ঙ

  Ketamine
• Headache after spinal anaesthesia
  ক

  Is less likely with a 27G than with a 25G needle

  খ

  Symptoms are more prominent in sitting position

  গ

  is unlikely to develop after 24 hours

  ঘ

  Is more frequent in the elderly

  ঙ

  May be accompanied by 6th cranial nerve palsy
• Inhalational anaesthetic agents. are
  ক

  Halothane

  খ

  Nitrous oxide

  গ

  Propofol

  ঘ

  Ketamine

  ঙ

  Oxygen
• Regarding intravenous anaesthetic agents
  ক

  Propofol produces less hangover effect postoperatively

  খ

  Thiopental sodium has antithyroid activity

  গ

  Thiopental sodium is a potent anticonvulsant agent

  ঘ

  Ketamine has no analgesic action

  ঙ

  Benzodiazepines increase intracranial pressure
• Side effects of suxamethonium are
  ক

  Bradycardia.

  খ

  Hyperkalemia

  গ

  Myalgia

  ঘ

  Decreased intracranial pressure

  ঙ

  Decreased intragastric pressure