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Cells deficient in hypoxanthine guanine phosphoribosyl-transferase (HPRT) enzyme rely on

Cells deficient in hypoxanthine guanine phosphoribosyl-transferase (HPRT) enzyme rely on Correct Answer Synthesis of purine deoxynucleotides by de novo pathway

Related Questions

Lesch-Nyhan syndrome is caused by the deficiency of the enzyme hypoxanthine-guanine phosphoribosyl transferase (HGPRT). Cells deficient in HGPRT die in a medium containing which of the following?
HAT (hypoxanthine, aminopterin and thymidine) is used for selecting the hybridomas based on the following
I. Only hybridoma will grow since it inherited the HGPRT genes from B-cells and can synthesize DNA from hypoxanthine.
II. Myeloma cells will not grow in cultures since de novo synthesis is blocked by aminopterin and due to the lack of HGPRT enzyme.
Cells deficient in hypoxanthine guanine phospho-ribosyl transferase (HGPRT)
Which of the following statement(s) is/are CORRECT for antigen activated effector T cells?
P. CD4+ cells make contact with macrophages and stimulate their microbicidal activity.
Q. CD4+ cells make contact with B cells and stimulate them to differentiate into plasma cells.
R. CD8+ cells make contact with B cells and stimulate them to differentiate into plasma cells.
S. CD8+ cells make contact with virus infected cells and kill them.
A hybrid derived from the fusion of a myeloma cell (HPRT−) with an antibody secreting B-lymphocyte (HPRT+) can be selected to produce monoclonal antibody by growing in a medium containing
In the question two statements are given, followed by two conclusions, I and II. Read all the conclusions and then decide which of the given conclusions logically follow/s from the given statements. Statements: All white blood cells are red blood cells. Some blood cells are red blood cells. Conclusions: I. All blood cells are red blood cells, is a possibility. II. Some red blood cells are not blood cells.
Consider the following statements and choose the correct answer:
1. Adenine pairs with thymine (A : T) and guanine with cytosine $$\left( {G \vdots C} \right)$$
2. Adenine and thymine are joined by three hydrogen bonds through atoms
3. Guanine and cytosine are joined by two hydrogen bonds through atoms
4. The weak hydrogen bonding enables the two strands of the DNA to separate during replication
Which of the following statements are NOT true? a) The number of cells in an elephant is more than number of cells in a monkey b) The size of cells in an elephant is larger than size of cells in a monkey c) Shape of cells in an elephant is different than shape of cells in a monkey
Consider the following statements regarding the Structure of cells: 1. Both Animal & Plant cells comprise amyloplast within the cell membrane. 2. Plant cells have plasmodesmata channels whilst animal cells do not. 3. Vacuoles in both plant cells & animal cells are always filled with solid substances. Which of the statement given above is/are not correct? 
Which of the following statements are correct regarding common differences between plant and animal cells?
1. Plant cells have cellulose cell wall, while animal cells lack it.
2. Plant cells lack plasma membrane, while animal cells have it.
3. Mature plant cell have a large vacuole, while animal cells have numerous small vacuoles.