The main buffer system of the human blood is

A H<sub>2</sub>CO<sub>3</sub> - HCO<sub>3</sub>
B H<sub>2</sub>CO<sub>3</sub> - CO<sub>3</sub><sup>2-</sup>
C CH<sub>3</sub>COOH - CH<sub>3</sub>COO<sup>-</sup>
D NH<sub>2</sub>CONH<sub>2</sub> - NH<sub>2</sub>CONH<sup>+</sup>

Correct Answer: H<sub>2</sub>CO<sub>3</sub> - HCO<sub>3</sub>

Bicarbonate buffer is the most important buffer system in blood plasma (generally in the extracellular fluid). This buffer consists of weak acid H2CO3(pK1 = 6,1) and conjugated base HCO3- (bicarbonate).

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