The activity of which of the following enzyme is inhibited by the chemotherapeutic agent during deoxyribonucleotide synthesis?

The activity of which of the following enzyme is inhibited by the chemotherapeutic agent during deoxyribonucleotide synthesis? Correct Answer Dihydrofolate reductase

Methotrexate and aminopterin are two anticancer drugs which inhibits the activity of dihydrofolate reductase. This will stop the formation of deoxyribonucleotide or DNA and the growth of the cell stops.

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