What are the characteristics of colonic release systems?
What are the characteristics of colonic release systems? Correct Answer Usage of polymers that dissolves only in the alkaline pH of colon
For the drug to be released in colon pH sensitive bio erodible polymers like polymethacrylates are used. These polymers release the medication only at the alkaline pH of colon. These are used for the treatment of ulcerative colitis. Also can use divinylbenzene polymers which will be cleaved by azoreductase.