How pH alteration of the drug microenvironment is done?

How pH alteration of the drug microenvironment is done? Correct Answer In situ salt formation

Alteration of pH of the drug microenvironment is done in two ways. One of that is in-situ salt formation, and other is the addition of buffers to the formulation e.g. buffered aspirin tablets. We cannot depend on tissue pH since it changes person to person.
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