Type IV Hypersensitivity reaction is accomplished by which two phases?
Type IV Hypersensitivity reaction is accomplished by which two phases? Correct Answer Sensitization phase and effector phase
Type IV hypersensitivity reaction is accomplished in two phases: the initial sensitization phase and the later effector phase. In the first phase, i.e., in sensitization phase, the most important mechanism takes place which is introducing a contact with antigens. During this phase, Th cells specific to that particular antigen in target bind and produce cytokines. In the second phase, i.e., in effector phase, the binding and exposure of that particular antigen gives rise to a delayed response to activate macrophages. This delayed response is therefore named as delayed type hypersensitivity. Once the macrophages are activated, they are directed to the targeted tissue for damage mechanism.