Which hemolytic disease is caused in new-borns due to the reaction of type II hypersensitivity?
Which hemolytic disease is caused in new-borns due to the reaction of type II hypersensitivity? Correct Answer Erythroblastosis fetalis
Hemolytic disease in new-born babies occurs due to type II hypersensitivity reaction. It takes place via maternal antibody isotype IgG which overlaps the placenta. This results in erythroblastosis fetalis. This case is very rare as it develops if an Rh- mother gives birth to Rh+ foetus. In such a condition, the maternal antibodies transmit to form fetal red blood cells and this results in incompatibility between maternal and fetal blood groups.