Which of these is not a cofactor?

Which of these is not a cofactor? Correct Answer Nickel

Nickel is a cofactor that is used by urease enzyme. Additional non protein chemical component required for optimum activity of enzymes is referred to as cofactors. Coenzyme is referred to as a complex organic or metallo-organic compound present in an enzyme. Cofactors are folic acid, biotin, coenzyme A, etc.
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