Enzymes MCQ 5+

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• What is an Isozyme?
  ক

  Same structure, different function

  খ

  Different structure, the same function

  গ

  Same structure, the same function

  ঘ

  Different structure, different function
• Name the enzyme which is found in tears, sweat, and an egg white?
  ক

  Ribozyme

  খ

  Lysozyme

  গ

  Zymogen

  ঘ

  Isozymes
• Lineweaver-Burk plot is also known as______
  ক

  Double reciprocal plot

  খ

  Hanes-Woolf plot

  গ

  Eadie-Hofstee plot

  ঘ

  Steady-state equation
• Which of the following is not an example of irreversible enzyme inhibitor?
  ক

  Cyanide

  খ

  Sarin

  গ

  Diisopropyl phosphoflouridate (DIPF)

  ঘ

  Statin drugs
• What is the SI unit of enzyme activity?
  ক

  Km

  খ

  Kat

  গ

  Kcat

  ঘ

  Vmax
• Which of the following is not a catalytic strategy for an enzyme to perform specific reaction?
  ক

  Covalent catalysis

  খ

  Metal ion catalysis

  গ

  Michaelis constant

  ঘ

  Acid-base catalysis
• Which of the following is INCORRECT for the lock-and-key model?
  ক

  It is used to describe the binding process

  খ

  The active site of the enzyme is complementary to the substrate

  গ

  It demonstrates enzyme-substrate complex

  ঘ

  The binding of the substrate produces a conformational change in enzyme
• What is the binding energy?
  ক

  Free energy released in the formation of enzyme-substrate interaction

  খ

  The energy required to form a bond

  গ

  The energy required to bind substrate

  ঘ

  It is the activation energy
• Which of the following is an example of ligases enzyme?
  ক

  Mutases

  খ

  Epimerases

  গ

  Racemases

  ঘ

  Carboxylases
• The zymogen is an inactive precursor of an active enzyme.
  ক

  True

  খ

  False
• Which of the following function is catalyzed by Racemases?
  ক

  Removal of water

  খ

  Intramolecular transfer of a functional group

  গ

  Interconversion of L and D stereoisomers

  ঘ

  Inversion of asymmetric carbon atom
• Which of the following reaction is catalyzed by Lyase?
  ক

  Breaking of bonds

  খ

  Formation of bonds

  গ

  Intramolecular rearrangement of bonds

  ঘ

  Transfer of group from one molecule to another
• Mark the CORRECT function of enzyme, Peptidase?
  ক

  Cleave phosphodiester bond

  খ

  Cleave amino bonds

  গ

  Remove phosphate from a substrate

  ঘ

  Removal of H2O
• What is the function of phosphorylase?
  ক

  Transfer inorganic phosphate

  খ

  Transfer a carboxylate group

  গ

  Use H2O2 as the electron acceptor

  ঘ

  Transfer amino group
• Name the enzyme which catalyzes the oxidation-reduction reaction?
  ক

  Transaminase

  খ

  Glutamine synthetase

  গ

  Phosphofructokinase

  ঘ

  Oxidoreductase
• Name the enzyme secreted by pancreas?
  ক

  Pepsin

  খ

  Chymotrypsin

  গ

  Trypsin

  ঘ

  Alcohol dehydrogenase
• Which of this vitamin is associated with the coenzyme Biocytin?
  ক

  Nicotinic acid

  খ

  Thiamine

  গ

  Biotin

  ঘ

  Pyridoxine
• Name the coenzyme of riboflavin (B2)?
  ক

  NAD or NADP

  খ

  FAD and FMN

  গ

  Coenzyme A

  ঘ

  Thiamine pyrophosphate
• What is an apoenzyme?
  ক

  It is a protein portion of an enzyme

  খ

  It is a non-protein group

  গ

  It is a complete, biologically active conjugated enzyme

  ঘ

  It is a prosthetic group
• What is the nature of an enzyme?
  ক

  Vitamin

  খ

  Lipid

  গ

  Carbohydrate

  ঘ

  Protein
• Enzyme increases the rate of reaction by lowering the activation energy.
  ক

  True

  খ

  False
• A __________is a biocatalyst that increases the rate of the reaction without being changed.
  ক

  Aluminum oxide

  খ

  Silicon dioxide

  গ

  Enzyme

  ঘ

  Hydrogen peroxide
• Head injures can be detected by _______
  ক

  increase of CK2 in blood

  খ

  increase of CK1 in CSF

  গ

  elevated levels of CK3 in serum

  ঘ

  LDH2 and LDH3 increase
• Which of the following is not a clinical application of creatine kinase isoenzyme?
  ক

  Hypothyroidism

  খ

  Damage of heart tissue

  গ

  Myopathy

  ঘ

  Leukemia
• Which is the only tissue which has mixed MB (CK2) isoenzyme?
  ক

  Prostate

  খ

  Liver

  গ

  Cardiac tissue

  ঘ

  Spleen
• CK1: brain:: CK3: _________________
  ক

  Kidney

  খ

  Spleen

  গ

  Skeletal muscle

  ঘ

  Cardiac tissue
• Which of the following is not true for creatine kinase?
  ক

  Its activity is greatest in striated muscle, brain and heart tissue

  খ

  It catalyzes L-lactate to pyruvate

  গ

  It is a dimer

  ঘ

  It has three isoenzymes
• Which of the following is not isoenzyme form of alkaline phosphatase?
  ক

  Bone

  খ

  Muscle

  গ

  Placenta

  ঘ

  Intestine
• Which of the following is not an isoenzyme of acid phosphatase?
  ক

  Prostate

  খ

  Liver

  গ

  Salivary

  ঘ

  Spleen
• LDH4 and LDH5: Bacterial meningitis:: LDH1 and LDH3: ___________
  ক

  Kidney malignancies

  খ

  Myocardial infarction

  গ

  Intracranial hemorrhage

  ঘ

  Viral meningitis