Which of the following displaces Importin-alpha from the cargo transported inside the nucleus?
Which of the following displaces Importin-alpha from the cargo transported inside the nucleus? Correct Answer CAS
Once the complex composed of importin-alpha—importin-beta—molecule enters the nucleus, the importin-alpha and importin-beta has to be removed. RanGTP binds to Importin-beta and displaces it from the complex. Then the Cellular Apoptosis Susceptibility (CAS) protein which is an exportin and is bound to RanGTP, displaces Importin-alpha from the molecule with NLS sequence.
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Feb 20, 2025