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The mutated and normal prion proteins associated with CJD have the same amino acid sequence.

The mutated and normal prion proteins associated with CJD have the same amino acid sequence. Correct Answer True

The mutated and normal versions of prion proteins are composed of same amino acid sequence, the only difference lies in the folded structure. The mutated version consists more of beta sheets whereas normal version has alpha helices.

Related Questions

Consider the following statements regarding genetic code and choose the correct answer:
1. The genetic code is degenerate
2. In all amino acids the first two bases are the same in all the codons that represent a particular amino acid
3. The number of codons an amino acid can claim is proportional to the frequency of the amino acid in proteins
4. Amino acids with codons ending in U or A also have codons ending in C or G respectively
Analysis of a hexapeptide using enzymatic cleavage reveals the following result:
• Amino acid composition of the peptide is: 2R, A, V, S, Y
• Trypsin digestion yields two fragments and the compositions are: (R, A, V) and (R, S, Y)
• Chymotrypsin digestion yields two fragments and the compositions are: (A, R, V, Y) and (R, S)
• Digestion with carboxypeptidase A yields no cleavage product.
Given: Trypsin cleaves at carboxyl side of R. Chymotrypsin cleaves at carboxyl side of Y. Carboxypeptidase A cleaves at amino side of the C-terminal amino acid (except R and K) of the peptide.
The correct amino acid sequence of the peptide is:
In a batch process, the reaction takes place in the presence of an acid medium. The acid is drained from the reaction vessel at the rate of 15ml/s as a result of the density difference of the acid from the reacting component. To avoid wastage of acid, it is recycled to an acid tank which has 1000 L capacity. The acid drained from the reaction vessel, picks up 50 g/L solids from the reactor. Acid is fed once again to the process from acid tank. When the process is started, the acid is almost pure in the tank as a result of filtration. As the reaction proceeds, acid in the tank gets more and more contaminated with the solids. The concentration of the solids should not exceed 100 g/L from the process point of view. The batch time is 16h. Estimate whether the concentration of the solids will exceed 100g/L during the batch reaction.
Consider the following statements related to Genetics. 1. Genetics is the study of heredity. 2. The genetic information lies within the cell nucleus of each living cell in the body.  3. Proteins are made up of one or more polypeptide chains, each of which is composed of a sequence of amino acids, and the DNA sequence of a gene (through an RNA intermediate) is used to produce a specific amino acid sequence. Which of the above statements is/are correct?
PROTPARS counts the minimum number of mutations to change a codon for the first amino acid into a codon for the second amino acid, but only scores those mutations in the mutational path that actually change the amino acid.
Histones have very high percentage of basic amino acids (15 - 30%). For this class of proteins which of the following reagents would be a suitable choice for generating peptides in determination of amino acid sequence of the protein
A group of cytosolic proteins is anchored to the cytoplasmic face of a membrane by a fatty acyl group attached to an amino acid at the N-terminal. Which of the following is that amino acid?
Solution-1 containing 10% nitric acid and 20% acetic acid at the rate F combines with Solution-2 containing 20% nitric acid and 10% acetic acid at the rate D, the product formed contains 30% nitric acid and 20% acetic acid at the rate P, how many independent equations containing F, D, and P are possible?
Solution-1 containing 10% hydrochloric acid and 20% acetic acid at the rate F combines with Solution-2 containing 20% hydrochloric acid and 30% acetic acid at the rate D, the product formed contains 20% hydrochloric acid and 30% acetic acid at the rate P, how many independent equations containing F, D, and P are possible?
A laboratory teacher had 1.5 litres of concentrated sulfuric acid. She replaces concentrated sulfuric acid with water after every class till the carton is empty. One student needs 10 ml of sulfuric acid mixture in every class. First class had 20 students and since then all other classes observed 10 students. Calculate total quantity of water with which mixture of sulfuric acid and water is replaced till carton is empty. Note 1.5 litres of concentrated sulfuric acid had 90% sulfuric acid and rest water