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In an experiment you develop immune response in mice against salmonella flagellar antigen. However, you observe the infection still persisted. Which if a likely possibility if immune system is functioning properly?

In an experiment you develop immune response in mice against salmonella flagellar antigen. However, you observe the infection still persisted. Which if a likely possibility if immune system is functioning properly? Correct Answer The flagella antigen changed

In salmonella, the flagellar antigen is target for immune response. His antigen’s phase can vary with presence of insertion sequence within the gene. In this case change of antigen could lead to a loss of specificity by the immune system.

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