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Doctors Medicines MCQs Q&A

Which antibiotic inhibits peptidyl transfer by blocking the accommodation of aa-tRNA into the peptidyl transferase (A/A) site?

Which antibiotic inhibits peptidyl transfer by blocking the accommodation of aa-tRNA into the peptidyl transferase (A/A) site? Correct Answer Tetracyclin

While chloramphenicol also blocks the peptidyl transferase activity, tetracycline does so by blocking the A site. Then the A site amino acid can’t interact with the P site one for the reaction to take place.

Related Questions

Which set of the following events occurs during the elongation step of translation?
P. Attachment of mRNA with the smaller subunit of ribosome
Q. Loading of correct aminoacyl-tRNA into the A site.
R. Formation of a peptide bond between the amino acyl-tRNA in the A site and the peptide chain that is attached to the peptidyl-tRNA in the P site.
S. Dissociation of the ribosomal subunits.
T. Translocation of peptidyl-tRNA from the A site to the P site of the ribosome.
Which of the following antibiotic acts by competitively inhibiting the peptidyl transferase activity of prokaryotic ribosomes?
Which of the following rRNA is intimately involved with the peptidyl transferase activity?
Which of the following blocks the peptidyl transferase of 80S eukaryotic ribosomes?
Which of the following rRNA molecules have peptidyl transferase activity in prokaryotes?
The peptidyl transferase center that catalyzes the peptide bond formation is located on the smaller subunit and consists entirely of rRNA.
The reaction to form a new peptide bond is known as the peptidyl transferase reaction.
The peptidyl transferase reaction is a result of ____________ consecutive steps.
The peptidyl transferase reaction center of the ribosome contains ___________ sites.
The ribosomal peptidyl transferase transfers ___________