Ribosome MCQ

Test your knowledge with important Ribosome MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 30+ more Ribosome MCQs on Bissoy. Bissoy App

• Name the antibiotic which inhibits protein synthesis in eukaryotes?
  ক

  Penicillin

  খ

  Cycloheximide

  গ

  Cinhonine

  ঘ

  Chlorophenicol
• Name the site where secreted protein synthesized?
  ক

  ER membrane bound ribosomes

  খ

  Mitochondrial ribosome

  গ

  Membrane free ribosome

  ঘ

  Chloroplast ribosome
• Which of the following transport involves translocation of the protein from cytosol to the nucleus?
  ক

  Transmembrane transport

  খ

  Vesicular transport

  গ

  Non-gated transport

  ঘ

  Gated transport
• Which of the following statement is defines polysomes?
  ক

  Lysosomal aggregation

  খ

  Multiple units of ribosomes

  গ

  Attachment of many ribosomes to common mRNA

  ঘ

  Attachment of many mRNA to ribosomes
• Which of the following is not a sorting signal present of protein?
  ক

  Signal patch

  খ

  Signal peptide

  গ

  Carbohydrate sequence

  ঘ

  Amino acid sequence
• Which of the following Scientist discovered ribosome for the first time?
  ক

  George Emil Palade

  খ

  Theodor Schwann

  গ

  Antonie van Leeuwenhoek

  ঘ

  Robert Hook
• What is the sedimentation coefficient of mitochondrial ribosome of humans?
  ক

  70S

  খ

  55S

  গ

  80S

  ঘ

  60S
• Which of the following ribosomal RNA does not take part in rDNA organization of E.coli?
  ক

  5S RNA

  খ

  23S RNA

  গ

  16S RNA

  ঘ

  5.8S RNA
• Eukaryotes have 80S ribosome.
  ক

  True

  খ

  False
• Genetic information stored in mRNA is translated to polypeptide by ___________
  ক

  Ribosome

  খ

  Nucleus

  গ

  Endoplasmic reticulum

  ঘ

  Golgi apparatus
• What will be DNA sequence of Shine and Dalgarno coding region?
  ক

  A/T rich

  খ

  C/G rich

  গ

  A/G rich

  ঘ

  C/T rich
• In an experiment you add streptomycin at low concentration first and then gradually increase the concentration till it completely inhibits peptide formation. What will be its effect at low concentration?
  ক

  No effect

  খ

  Shorter peptide

  গ

  Wrong amino acid incorporation

  ঘ

  Slower formation
• The ribosome slides over the mRNA translating it.
  ক

  True

  খ

  False
• Which of the antibiotic can halt translocation of the ribosome bound to the mRNA?
  ক

  Fusidic acid

  খ

  Streptomycin

  গ

  Rifampicin

  ঘ

  Chloramphenicol
• Which antibiotic inhibits peptidyl transfer by blocking the accommodation of aa-tRNA into the peptidyl transferase (A/A) site?
  ক

  Chloramphenicol

  খ

  Penicillin

  গ

  Tetracyclin

  ঘ

  Viomycin
• In an experiment you add rifampicin and paramomycin to the ribosome and mRNA mixture. What will inhibit theribosomal translation efficiency and how?
  ক

  Rifampicin will prevent translation initiation

  খ

  Paramomycin will slow down translation

  গ

  Rifampicin will bind irreversibly to the ribosome and inactivate it

  ঘ

  Paramomycin will increase error rate
• Puromycin is a ribosomal antibiotic. It binds to ________
  ক

  Peptide exit channel

  খ

  16S rRNA

  গ

  tRNA binding site

  ঘ

  A site of unassociated 16S rRNA
• The catalytic activity of the ribosome is located in the ______
  ক

  Proteins

  খ

  50S ribosomal rRNA

  গ

  30S ribosomal rRNA

  ঘ

  Undiscovered
• The Shine and Dalgarno is located in ____________
  ক

  5.8S rRNA ~ 20 nucleotide upstream to start site

  খ

  mRNA ~ 10 nucleotide upstream to start site

  গ

  16S rRNA ~ 10 nucleotide upstream to start site

  ঘ

  23S rRNA ~ 10 nucleotide upstream to start site
• State whether the enzyme PDF is a novel drug target for antibiotics.
  ক

  True

  খ

  False
• The 50S ribosomal subunit is folded in ______ major domains.
  ক

  20

  খ

  4

  গ

  10

  ঘ

  6
• The f-Met tRNA binds to ribosomal _______ site
  ক

  P

  খ

  A

  গ

  E

  ঘ

  G
• Methionine amino peptidase will remove the N terminal formyl methionine if the N+1 amino acid is_________
  ক

  Glycine

  খ

  Phenyl alanine

  গ

  Methionine

  ঘ

  Tyrosine
• Which metal acts as a cofactor for Methionyl aminopeptidase?
  ক

  Mg2+

  খ

  Zn2+

  গ

  Co2+

  ঘ

  Mn2+
• The tRNA f-Met-tRNA binds to __________
  ক

  Formyl methinone

  খ

  Formic acid

  গ

  Metionine

  ঘ

  Glutamine
• The ribosomal peptidyl transferase transfers ___________
  ক

  An isolated amino acid to the peptide chain

  খ

  A peptide chain to an amino acid

  গ

  A peptide chain to another peptide chain

  ঘ

  An amino acid to a tRNA
• Which ribosome recognized the transcription initiation site of the mRNA?
  ক

  23S

  খ

  5S

  গ

  5.8S

  ঘ

  18S
• Which of this is not a ribosomal protein?
  ক

  L21

  খ

  S34

  গ

  L4

  ঘ

  S21
• If you gradually decrease the Mg2+ concentration of the solution of ribosomes, what will you expect?
  ক

  The subunits will associate faster

  খ

  The subunits will dissociate

  গ

  rRNA will separate from its protein

  ঘ

  The two subunits will dissociate into its rRNA
• Which of these is transcribed by RNA pol III?
  ক

  28S

  খ

  16S

  গ

  5.8S

  ঘ

  5S