You wanted to find out the importance of the DNA polymerases. So, you mutated the polymerases one by one and checked for survival. In which of these mutant cases will you see least survival rate?
You wanted to find out the importance of the DNA polymerases. So, you mutated the polymerases one by one and checked for survival. In which of these mutant cases will you see least survival rate? Correct Answer Alpha
Alpha has primase activity. Without a primer DNA synthesis can’t initiate thus Alpha polymerase is indispensible. While the beta is mainly needed for repair mechanisms it doesn’t make much difference. However, delta and eta are main polymerases for eukaryotes and their mutation will have major effects as well.
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Feb 20, 2025