Which of the following antibiotic is not involved in the inhibition of specific enzyme systems?

Which of the following antibiotic is not involved in the inhibition of specific enzyme systems? Correct Answer Sulphonamides

The sulphonamides have their antibacterial attack directed towards a specific essential enzyme. Their structure is related to p-aminobenzoic acid (PABA) which is a precursor to their synthesis of the essential coenzyme tetrahydrofolic acid (THFA).
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