Which of the following is a wrong statement?

A To assume biological activity, many nascent polypeptides have to be covalently modified before or after the folding process
B In eukaryotic cells most modifications take place in the endoplasmic reticulum and the Golgi apparatus
C The modifications in eukaryotic cells include proteolytic cleavage; formation of disulfide bonds; addition of phosphoryl, methyl, acetyl, or other groups onto certain amino acid residues
D The modifications in eukaryotic cells doesn’t include attachment of oligosaccharides or prosthetic groups to create mature proteins

Correct Answer: The modifications in eukaryotic cells doesn’t include attachment of oligosaccharides or prosthetic groups to create mature proteins

Post translational modifications have a great impact on protein function by altering the size, hydrophobicity and overall conformation of the proteins. The modifications can directly influence protein–protein interactions and distribution of proteins to different subcellular locations.
Bissoy MCQ
#Bioinformatics #Post translational Modification

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