Which of the following toxin does not have ADP-ribosylation activity?
Which of the following toxin does not have ADP-ribosylation activity? Correct Answer Botulinum toxin A
Botulinum toxin A does not have ADP-ribosylation activity. Pertussis toxin, Cholera toxin, and E. coli heat-labile toxins have ADP-ribosylation activity. In the ADP-ribosylation reaction, the toxins bind NAD and transfer the ADP-ribose moiety to the major target protein.