Binding of metal ions or cofactors can increase structural stability when they bind with higher affinity to the folded than to the unfolded state.

Binding of metal ions or cofactors can increase structural stability when they bind with higher affinity to the folded than to the unfolded state. Correct Answer True

The above statement is true. Binding of metal ions or cofactors can increase structural stability when they bind with higher affinity to the folded than to the unfolded state. Binding sites for metal ions, frequently Ca+2, Zn+2, Cu+2 aims to enhance protein stability.
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