Bissoy.com
Doctors Medicines MCQs Q&A

Which of the chromosome mutation leads to Beta-thalassemia?

Which of the chromosome mutation leads to Beta-thalassemia? Correct Answer 11

The mutation in the HBB gene on chromosome number 11 leads to the disorder beta-thalassemia. It is inherited as an autosomal recessive trait. The severity of beta-thalassemia depends upon the nature of the mutation.

Related Questions

Which of the following pairs are correctly matched ? A. Missense mutation - Substitution of one amino acid for another B. Nonsense mutation - The altéred DNA sequence is a stop codon C. Frame shift mutation - The subsequent amino acids are altered D. Silent mutation - There is no change in the DNA sequence
Which of the following is/are true? i. All children will inherit an X chromosome from their mothers. ii. All children will inherit a Y chromosome from their mothers. iii. A child who inherits an X chromosome from the father will be a boy. iv. A child who inherits an X chromosome from the father will be a girl.
Consider the following statements regarding Mutation in genes: 1. Effects of mutation in somatic cells are observed in offspring whilst germ cells are not. 2. Chromosomal mutation may occur due to the absence of one or more chromosomes or some portion of it. Which of the statements given above is/are correct? 
Assertion (A) Human beings have 23 pair of chromosomes, one of which is the sex chromosomes and the remaining are 22 autosomes. The X-linked disease are related to mutation on a sex chromosomes.
Reason (R) Colour blindness results from a mutation in X-chromosome.
Consider the following statements and choose the correct answer:
1. Since chromosomal aberrations result in a change in the organism, they are also called chromosomal mutation
2. Chromosomal aberrations are of four types deletion, duplication, inversion and translocation
3. If a single break occurs near the end of a chromosome, it results in an intercalary deletion
4. A deficiency involves loss of a chromosome section
Consider the following statements with regard to the functions of the centromere in the chromosome.
1. Centromeres are the centres of movement of the chromatids or chromosomes during anaphase separation.
2. Acentric chromosomes lack the capacity to segregate in a regular fashion.
3. Crosing-over in one arm of a metacentric chromosome does not affect the crossing over in the arm of the same chromosome.
Which of the statements given above are correct?
If two breaks occur in one chromosome, and one in a non-homologous one, the fragment from the first chromosome may become joined in an intercalary position in the second chromosome. This is a case of
A male plant of chromosome pp pollinates the plant having chromosome type PP. The expected chromosome in embryo and endosperm
Consider the following statements regarding centromere and choose the correct answer:
1. The position of the centromere is constant for a particular chromosome
2. The structure and function of the centromere are different from that of the rest of the chromosome
3. During division the centromere is functional, while the rest of the chromosome is genetically inactive
4. The position of the centromere varies in different chromosomes
In the question below are given three statements followed by four conclusions numbered I, II, III, IV. You have to take the given statements to be true even if they seem to be at variance with commonly known facts. Read all the conclusions and then decide which of the following conclusions logically follows from the given statements disregarding commonly known facts. Statements: All sands are golds. No silver is a gold. Some silvers are leads. Conclusions: I) No sand is a gold. II) Some leads are not golds. III) Some sands are silvers. IV) Some leads are sand.