By which of the following defects, thalassemia is caused?

By which of the following defects, thalassemia is caused? Correct Answer Defects in RBCs

The defect in the synthesis of globin polypeptide in RBC causes a group of disorders known as thalassemia. Absence or reduced synthesis of one of the globin chains leads to the excess of other chains which accumulate in our body to causes different diseases.

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Pareto chart identifies the ____________ defects not the ____________ defects.