Following statement(s) is (are) true regarding haemolytic uraemic syndrome (HUS)

A Antibiotics may paradoxically increase shiga toxin release
B Eculizumab blocks complement activities by cleavage of C5
C Plasma exchange significantly improve the outcome
D Microangiopathic hemolytic anaemia is a characteristic feature
E Rickettsial infection associated with diarrhoea associated (D+) HUS

Correct Answer: Antibiotics may paradoxically increase shiga toxin release, Eculizumab blocks complement activities by cleavage of C5, Plasma exchange significantly improve the outcome, Microangiopathic hemolytic anaemia is a characteristic feature

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#MD #Hematology #Haemolytic uremic syndrome

Related Questions

The followings are the components of haemolytic Uraemic syndrome
A Uremia
B Hemolytic anemia
C Thrombocytopenia
D Heart failure
E Leucopenia
Haemolytic uremic syndrome is characterized by
A Microangiopathic haemolytic anaemia
B Azotemia
C Thrombocytopenic purpura
D Leukocytoclastic vasculitis
E Arthritis
Antibodie(s) responsible for immediate haemolytic transfusion reaction is (are)
A Anti-A
B Anti-K
C Anti-JKa
D Anti-H
E Anti-Fyb
Which test can be used to detect haemolytic anemia
A Coomb’s test
B Peripheral blood smear examination
C Reticulocyte count
D Occult blood test
E Schilling test
Haemolytic jaundice is associated with
A Increase in the concentration of bilirubin diglucoronide in the bile
B Increase in urobilinogen in urine
C Presence of bilirubin in urine
D Increase in the serum alkaline phosphatase
E Decrease in unconjugated bilirubin in the serum
Haemolytic disease of newborn HDN is associated with involvement of
A IgG
B IgG + complement
C IgM
D IgA
E IgD
Haemolytic diseases of the newborn include
A ABO incompatibility
B Vitamin K1 deficiency
C Glucose-6-phosphate dehydrogenase deficiency
D Sickle cell trait
E Hereditary spherocytosis
Congenital haemolytic disorders are
A Thalassaemia
B Elliptocytosis
C G-6PD deficiency
D March haemoglobinuria
E Micro-angiopathic haemolytic anaemia
Causes of micro-angiopathic haemolytic anaemia are
A Haemolytic uraemic syndrome
B Meningococcal septicemia
C Chronic renal disease
D Systemic lupus erythematosus
E Falciparum malaria
Regarding Zollinger-Ellison syndrome
A It is peptic ulcer
B Gastrinoma may be associated
C It may occur outside the stomach
D It is not fulminating type
E Gastric pH may be high

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