The following enzyme deficiencies lead to hemolytic anemia

Features of hemolytic anemia include

A

Increased reticulocyte count

B

Reduced haptoglobin

C

Raised LDH

D

Microcytic blood Picture

E

Increased conjugated bilirubin

Hereditary hemolytic anemia is

A

Thalassemia

B

Aplastic anemia

C

Megaloblastic anemia

D

Leukemia

Following enzyme deficiency leads to hemolytic anaemia

A

Pyruvate kinase

B

Glucose 6-phosphate dehydrogenase

C

Lactate dehydrogenase

D

Pyruvate dehydrogenase complex

E

NADPH oxidase

Diagnosis of hemolytic uremic syndrome is based on the following feature/s

A

Azotemia

B

Thrombocytopenia

C

Increased LDH

D

Hematuria

E

Neutropenia

Which of the following factors are associated with Hemolytic uremic syndrome?

A

Factor I

B

Factor B

C

Factor D

D

Factor H

Laboratory features present in hemolytic jaundice are

A

Raised serum bilirubin

B

Increased urobilinogen in urine

C

High serum alkaline phosphatase [Davidson's/P-852]

D

Presence of bilirubin in urine

E

Decreased stercobilinogen in stool

Which hemolytic disease is caused in new-borns due to the reaction of type II hypersensitivity?

A

Erythroblastosis fetalis

B

Haemorrhagic disease

C

Newborn jaundice

D

Neonatal infection

Which proteolytic enzyme was used in the experiments aimed at elucidating the mutation that causes sickle cell anemia?

A

papain

B

rennin

C

pepsin

D

trypsin

Statement 1: Enzyme reaction is dependent of concentration on enzyme only and not substrate. Statement 2: Do enzymes catalase and peroxidase show residual enzyme activity?

A

True, False

B

True, True

C

False, False

D

False, True

When the enzyme solubility is reduced by reducing the water availability, the enzyme-enzyme interaction start to take place and they will aggregate to form precipitates. This phenomenon is called ______________

A

salting in

B

salting out

C

precipitation

D

chromatography

The following enzyme deficiencies lead to hemolytic anemia

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