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Hemoglobin appears in which stage of Erythropoiesis?

Hemoglobin appears in which stage of Erythropoiesis? Correct Answer Intermediate Normoblast stage

Concept

Erythropoiesis is the process that produces red blood cells.

Stages of erythropoiesis are

  • Basophilic normoblast (early normoblast)
  • Polychromatic normoblast (intermediate normoblast)
  • Orthochromatic normoblast (late normoblast)

Explanation- 

Intermediate normoblast

  • It is also known as Polychromatic normoblast.
  • It is the last precursor cell capable of mitosis and is smaller than the basophilic erythroblast.
  • The cytoplasm appears greyer due to the presence of haemoglobin.
  • In this stage, Cell is smaller.
  • The nucleus is present in this stage.
  • Haemoglobin appears in this stage

Additional Information 

  Late Normoblast stage

  • It is also known as Orthochromatic erythroblast.
  • It is incapable of cell division.
  • Slightly larger than a mature erythrocyte.
  • It contains a small dense nucleus

Early Normoblast stage

  • It is also known as the Basophilic erythroblast.
  • It is smaller than the proerythroblast.
  • It is having a smaller nucleus and more basophilic cytoplasm.
  • It is involved in the production of haemoglobin.

Reticulocyte stage

  • It is also known as Polychromatophilic erythrocyte.
  • It is formed when the nucleus is extruded from the normoblast.
  • It contains some ribosomes and therefore retains a slight basophilic stain.
  • Cells can carry oxygen and enter the bloodstream and are found in low concentrations in normal blood

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