Match the Syndrome in the column - I with Karyotype in the column - II and select the answer which is not correct : Column – I Column – II A) Edward’s Syndrome Trisomy 18 B) Patau’s Syndrome Trisomy 13 C) Turner’s Syndrome Trisomy 21 D) Klinefelter’s Syndrome XXY

Match the Syndrome in the column - I with Karyotype in the column - II and select the answer which is not correct : Column – I Column – II A) Edward’s Syndrome Trisomy 18 B) Patau’s Syndrome Trisomy 13 C) Turner’s Syndrome Trisomy 21 D) Klinefelter’s Syndrome XXY Correct Answer C

The correct answer is C.

• Turner syndrome or the presence of only a single X chromosome in females.

​Important Points

• Some of the most common chromosomal abnormalities include:
  • Down's syndrome or trisomy 21.
  • Edward's syndrome or trisomy 18.
  • Patau syndrome or trisomy 13.
  • Klinefelter's syndrome or the presence of additional X chromosome in males.
  • Turner syndrome or the presence of only a single X chromosome in females.
  • XYY syndrome and XXX syndrome.

​Key Points

• There are three types of genetic disorders:
  • Single-gene disorders:
    • Where a mutation affects one gene. Sickle cell anaemia is an example.
  • Chromosomal disorders:
    • Where chromosomes (or parts of chromosomes) are missing or changed.
  • Complex disorders:
    • Where there are mutations in two or more genes.