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Which is a chronic inflammatory and autoimmune disease affecting peripheral synovial joints of bone?

Which is a chronic inflammatory and autoimmune disease affecting peripheral synovial joints of bone? Correct Answer Rheumatoid

Concept:-

  • Rheumatoid arthritis (RA) is an autoimmune disorder. Where the immune system attacks its own body cells leading to inflammation.
  • It particularly affects joints in the hands, wrists, and knees.
  • It may also affect other tissues in the lungs, heart, and eyes.
  • Symptoms of RA:
    • Joint pain
    • Stiffness, swelling, and tenderness in the joint or joints
    • Weight loss
    • Fever
    • Fatigue

Explanation:

  • The specific test for RA:
    • Antinuclear body test
    • C-reactive protein test
    • ESR
    • RF test
    • Cyclic citrullinated peptide antibodies
    • Complement body test
    • Synovial fluid analysis
  • RA may result in bone erosion and joint deformity.

Treatment:

  • NSAIDS
  • Steroids: Prednisone
  • DMARDS
  • Physical or occupational therapy
  • Surgery: Synovectomy, tendon repair, and total joint replacement.

Additional Information

  • Osteoarthritis is the wear-tear of the cartilage bones. It occurs in old age.
  • Polyarthritis refers to arthritis affecting more than five joints.
  • Ankylosing spondylitis is associated with vertebrae.

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