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Doctors Medicines MCQs Q&A

Which of the following drugs is used in Hypertensive crisis?

Which of the following drugs is used in Hypertensive crisis? Correct Answer <span style="">Sodium nitroprusside</span>

Concept:-

Hypertensive crisis: it is a clinical syndrome that is associated with an abrupt, a marked increase in blood pressure “relative to the patient’s baseline” and causes acute or rapidly progressing end-organ damage.

It includes

  • Hypertensive urgency
  • Hypertensive emergency

Explanation:

Sodium nitroprusside:

  • It has a vasodilator effect on the smooth muscle of the venoarteriolar beds.
  • It is rapidly metabolized in red cells to cyanide, which is then metabolized to thiocyanate prior to renal excretion.

Uses:

  • Hypertensive encephalopathy
  • Refractory cases of congestive heart failure.

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