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Consider the following pairs of vaccine and category/type: 1. Covaxin: Inactivated pathogen-based vaccine 2. Covishield: mRNA vaccine 3. Sputnik V : Viral vector-based vaccine Which of the pairs given above is/are correctly matched?

Consider the following pairs of vaccine and category/type: 1. Covaxin: Inactivated pathogen-based vaccine 2. Covishield: mRNA vaccine 3. Sputnik V : Viral vector-based vaccine Which of the pairs given above is/are correctly matched? Correct Answer 1 and 3 only

The correct answer is 1 and 3 only.

Key Points

  • Covaxin:
    • ​It is an inactivated pathogen-based vaccine.
    • It is developed with Whole-Virion Inactivated Vero Cell-derived technology.
    • They contain inactivated viruses, which can not infect a person but still can teach the immune system to prepare a defence mechanism against the active virus.
  • Covishield:
    • It ​is a recombinant, replication-deficient chimpanzee adenovirus vector vaccine.
    • It has been modified to enable it to carry the COVID-19 spike protein into the cells of humans. 
    • Hence, statement 2 is incorrect.
  • Sputnik V:
    • It is a viral vector vaccine designed to produce lasting immunity against COVID-19.
    • It is based on adenovirus DNA.
    • Adenovirus is used as a carrier to deliver the coronavirus gene to cells and synthesize the SARS-CoV-2 virus's envelope proteins, introducing the immune system to a potential enemy.
    • The cells then use the gene to produce the spike protein. A person's immune system will treat this spike protein as foreign and produce natural defences, antibodies, and T cells, against this protein.

Related Questions

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