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Declomycin 150 Tablet contains Demeclocycline Hydrochloride
Declomycin 150 Tablet side effects
Photosensitivity, reversible nephrogenic diabetes insipidus, permanent discolouration of the teeth, brownish-black microscopic discolouration of thyroid tissue, nausea, vomiting, diarrhoea, increases in LFT values, hepatitis, jaundice, hepatic failure, rashes, pruritus, bullous dermatoses, exfoliative dermatitis, skin discolouration, pseudotumour cerebri in adults and bulging fontanelles in infants, headache, dizziness, visual disturbances, impaired hearing, urticaria, angioneurotic oedema, pericarditis, anaemia, thrombocytopenia, neutropenia, agranulocytosis, eosinophilia.
Patients with pre-existing SLE and myasthenia gravis. Hepatic and renal impairment. Pregnancy.
Reduced absorption with antacids containing Al, Mg, or Ca, Fe-containing preparations, zinc, kaolin, quinapril, strontium ranelate, sucralfate, tripotassium dicitratobismuthate. May reduce the efficacy of oral contraceptives and penicillins. Increased risk of benign intracranial HTN with retinoids (e.g. acitretin, isotretinoin, tretinoin). Increased risk of ergotism with ergotamine and methysergide. May inactivate oral typhoid vaccine. May potentiate the effect of anticoagulants.
Pregnancy Category D. There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Hypersensitivity to demeclocycline or other tetracyclines. Lactation. Concurrent use with methoxyflurane.
Hepatic Impairment: Max: 1 gm daily.
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