1 Answers
Clit Syrup contains Chloroquine Phosphate
Clit Syrup uses for
Chloroquine Phosphate is indicated in the treatment of malaria, prophylaxis and suppression of malaria, amoebic hepatitis and abscess, discoid and systemic and systemic lupus erythematosus, rheumatoid arthritis
Acute malaria:
- Adult: As base: Initially, 600 mg followed by 300 mg 6 hr later on day 1. On days 2 and 3, single doses of 300 mg/day.
- Child: Initially, 10 mg base/kg (max 600 mg base) followed by 5 mg base/kg (max 300 mg base) after 6 hrs. Single doses of 5 mg base/kg on days 2 and 3.
Hepatic amoebiasis:
- Adult: As base: 600 mg daily for 2 days then 300 mg daily for 2 or 3 wk given with emetine or dehydroemetine.
- Child: 6 mg/kg daily. Max dose: 300 mg daily.
Rheumatoid arthritis:
- Adult: As base: 150 mg daily. Max: 2.5 mg/kg daily. Discontinue treatment if there is no improvement after 6 mth.
- Child: Up to 3 mg/kg/day. Discontinue treatment if there is no improvement after 6 mth.
Discoid and systemic lupus erythematosus:
- Adult: As base: Initially, 150 mg once daily, reduce gradually after maximal response. Max dose: 2.5 mg/kg daily.
- Child: 3 mg/kg daily.
Prophylaxis of malaria:
- Adult: As base: 300 mg once wkly, starting 1 wk before exposure, continuing throughout on a wkly basis and for at least 4 wk after exposure.
- Child: 5 mg/kg weekly.
Symptoms: Headache, drowsiness, visual disturbances, nausea and vomiting, CV collapse, shock and convulsions followed by sudden and early respiratory and cardiac arrest. ECG may reveal atrial standstill, nodal rhythm, prolonged intraventricular conduction time and progressive bradycardia leading to ventricular fibrillation and/or arrest.
Management: Treatment is symptomatic and should be prompt with immediate evacuation of the stomach by emesis or gastric lavage. Finely powdered, activated charcoal may be used within 30 min after ingestion of the antimalarial to reduce intestinal absorption of the drug. To be effective, the dose of activated charcoal should be at least five times the estimated dose of chloroquine ingested.
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