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Centoxin Tablet contains Digoxin
Centoxin Tablet uses for
Digoxin is indicated in:
- Heart failure
- Atrial fibrillation with an uncontrolled ventricular rate
- Acute left ventricular failure
- Chronic left ventricular failure and congestive heart failure, especially when caused by hypertensive valvular (especially mitral valvular) disease or ischaemic heart disease.
For rapid action: 1 to 1.5 mg in divided doses over 24 hours
For less urgent digitalisation: 0.25 to 0.5 mg daily(higher dose may be divided); Maintenance: 0.0625 to 0.5 mg daily (higher dose may be divided) accordingly to renal function and in atrial fibrilation on heart rate response;
Usual dose: 0.125 to 0.25 mg daily (lower dose my be appropriate in elderly).
Symptoms: Hyperkalaemia, cardiac arrhythmias and heart block.
Management: Treatment is symptomatic and supportive. Reduce absorption by gastric lavage if present within 30 min of ingestion. Do not induce vomiting or attempt passage of a gastric tube if presented >2 hr after ingestion or already has toxic manifestations, as this may induce an acute vagal episode and worsen digitalis-related arrhythmias. Activated charcoal is helpful in reducing drug absorption.
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