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Ifamide IV Infusion contains Ifosfamide
Ifamide IV Infusion uses for
Ifosfamide is indicated for use in combination with certain other approved antineoplastic agents for third-line chemotherapy of germ cell testicular cancer. It should be used in combination with Mesna for prophylaxis of hemorrhagic cystitis.
Lymphoma, Sarcoma, Solid tumours: Different licensed dosage regimens are available.
- Regimen 1: 82 gm/m2 divided over 3 days, repeat course every 2 wk.
- Regimen 2: 6 gm/m2 divided over 5 days, repeat course every 3 wk.
- Regimen 3: 5 gm/m2 (max: 10 gm), give as a single 24-hr infusion, repeat course every 3 wkly.
Germ cell testicular carcinoma: 1.2 gm/m2/day for 5 days via slow infusion over at least 30 minutes, repeat treatment every 3 wk or after recovery from haematological toxicity. To be given with mesna and adequate hydration of at least 2 L of oral or IV fluid per day.
Add 20 ml of sterile water for inj or sterile bacteriostatic water for inj containing benzyl alcohol or parabens for each 1 g of the drug to produce solutions of 50 mg/ml.
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