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Malarium Tablet contains Mefloquine
Malarium Tablet uses for
Mefloquine is indicated in-
- Acute Malaria Infections caused by Mefloquine-susceptible strains of Plasmodium falciparum (both chloroquine- susceptible and resistant strains) or by P. vivax
- Prophylaxis of P. falciparum and P. vivax malaria infections
Adult:
- Malaria prevention: 1 tablet (250 mg) once per week starting 1 weeks before departure and continued for 4 weeks after leaving malarious area.
- Malaria treatment: 5 tablets (5 x 250 mg) in a single dose (up to max. 1.5 gm) or preferably in 2 divided doses 6 to 8 hours apart.
In Children 6 Months and Older:
- Malaria prevention: Approximately 5 mg/kg body weight once per week (250 mg for children weighing over 45 kg, decreasing in proportion to body weight for children weighing 45 kg or less).
- Malaria treatment: 20 to 25 mg/kg body weight which may be split into two doses 6 to 8 hours apart to reduce the occurrence or severity of adverse reactions.
Geriatric Use: Experiences have not identified differences in responses between the elderly and younger patients.
Should be taken with food. Best taken with meals & a full glass of water.
In cases of overdosage with Mefloquine, the symptoms may be more pronounced. The following procedure is recommended in case of overdosage:
- Induce vomiting or perform gastric lavage, as appropriate.
- Monitor cardiac function (if possible by ECG), neurologic and psychiatric status for at least 24 hours.
- Provide Symptomatic and intensive supportive treatment as required, particularly of cardiovascular disturbance.
- Treat vomiting or diarrhoea with standard fluid therapy.
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